No difference between placebo, amitriptyline and topiramate in reducing pediatric migraine: The CHAMP trial

1. In this study, no significant intergroup differences between amitriptyline, topiramate and placebo for reduction in total number of headache days was observed. 2. Amitriptyline...

Radiolabeled somatostatin analogue linked with improved survival in neuroendocrine tumors

1. 177Lu-Dotatate, a radiolabeled somatostatin analogue, was associated with increased progression-free survival and decreased overall mortality compared to standard therapy in the treatment of...

Tranexamic acid reduces bleeding risk during coronary artery surgery: The ATACAS trial

1. Tranexamic acid demonstrated a significantly lower risk of bleeding complications and transfusion requirements compared to placebo in patients undergoing coronary artery surgery. 2. There...

“Weekend Warrior” physical activity patterns linked to lower mortality

1. In this analysis of questionnaire data from surveillance studies in England and Scotland, the pattern of physical activity consisting of one to two...

Breast cancer screening associated with substantial overdiagnosis in Danish study

1. In this retrospective cohort, breast cancer screening was not associated with a reduction in advanced tumors. 2. Breast cancer screening was associated with higher...

Pay-for-performance programs may be linked to process-of-care improvements in ambulatory settings

1. In ambulatory settings, pay-for-performance (P4P) programs may be correlated with improvements in processes of care. 2. Neither hospital nor ambulatory settings have shown uniform...

Physical activity may limit depressive symptoms in children

1. In a study of Norwegian children, those who engaged in more moderate to vigorous physical activity (MVPA) at ages 6 and 8 had...

AKI associated with increased mortality among critically ill children and young adults: The AWARE...

1. The study demonstrated that acute kidney injury (AKI) is common in critically ill children and young adults, and is associated with increased mortality. 2....

Ticagrelor and clopidogrel similar in preventing cardiovascular events in PAD: The EUCLID trial

1. In patients with peripheral arterial disease (PAD), there were no significant differences between ticagrelor and clopidogrel therapy in terms of the risk of...

Fish oil and aspirin did not reduce arteriovenous fistula failure: The FAVOURED trail

1. In this multi-center, international, randomized, controlled trial, use of fish oil supplementatio at the time of arteriovenous fistula (AVF) creation was not associated...
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