Recurrent Clostridium difficile infection associated with gastric acid suppression

1. In this systematic review and meta-analysis of observational data, gastric acid suppression was associated with increased risk of recurrent Clostridium difficile infection (CDI). 2....

Dietary supplementation with vitamin D and calcium not associated with reduced cancer risk in...

1. Vitamin D and calcium supplementation does not result in lower incidence of all-type cancer in post-menopausal women. Evidence Rating Level: 1 (Excellent) Study Rundown: With...

A virtual glucose management service significantly improved glycemic control in hospitalized patients

1. Implementation of the virtual glucose management service reduced the number of severe hypoglycemic events experienced by hospitalized adult inpatients. 2. The proportion of both...

A single glucocorticoid injection provides only short-term relief from chronic low back pain

1. Single glucocorticoid injections provided symptomatic relief from chronic low back pain after one month. 2. No differences in low back pain were observed between...

Multiple oral direct-acting antiviral regimens associated with sustained virologic response for hepatitis C virus...

1. Multiple oral direct-acting antiviral (DAA) interferon-free therapies with high SVR rates are available for all six hepatitis C virus (HCV) genotypes. 2. These DAA...

AAP issues policy statement on children in kinship care

Statement Rundown: There is growing evidence that children unable to live with their biological parents fare better when living with extended family rather than nonrelated...

Reduced yet persistent incidence of vertical HIV transmission in the United States

1. Overall incidence of vertical HIV transmission in the United States decreased from 2002 to 2013, and currently is at an estimated 1.75 per...

Effective subcutaneous C1-inhibitor for hereditary angioedema prophylaxis: The COMPACT trial

1. The self-administered, subcutaneous C1-inhibitor CSL830 demonstrated a dose-dependent high efficacy in the prophylactic treatment of hereditary angioedema (HAE) attacks compared to placebo. 2. CSL830...

Antioxidant supplementation did not decrease risk of dementia in older asymptomatic men: The PREADViSE...

1. Based on this double-blind randomized, controlled trial which evolved into a cohort study, asymptomatic men taking vitamin E, selenium or a combination of...

Canadians with cystic fibrosis have a significant survival advantage over American patients

1. After adjusting for risk factors associated with survival, Canadian patients had a median age of survival that was 10 years greater than in...
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