Oncology

Reports of high-impact oncology studies by medical professionals

Radiolabeled somatostatin analogue linked with improved survival in neuroendocrine tumors

1. 177Lu-Dotatate, a radiolabeled somatostatin analogue, was associated with increased progression-free survival and decreased overall mortality compared to standard therapy in the treatment of...

Breast cancer screening associated with substantial overdiagnosis in Danish study

1. In this retrospective cohort, breast cancer screening was not associated with a reduction in advanced tumors. 2. Breast cancer screening was associated with higher...

New treatment target for paclitaxel-induced pain [PreClinical]

1. In mouse models, the lipid metabolite 9,10 EpOME was identified as an important mediator of paclitaxel-induced peripheral neuropathic pain (PIPN). 2. Following the...

Sunitinib increases disease free survival in high risk renal carcinoma post nephrectomy

1. In patients with locoregional clear-cell renal cell carcinoma (RCC) at high risk of recurrence post nephrectomy, those taking sunitinib had a significantly longer...

Niraparib may lengthen progression-free survival for patients with recurrent ovarian cancer

1. Among patients with platinum-sensitive recurrent ovarian cancer, those who received the PARP inhibitor niraparib demonstrated significantly increased progression-free survival compared to patients who...

Palliative care intervention improves quality of life during hospitalization for hematopoietic stem cell transplantation

1. Palliative care involvement helps lessen quality of life (QOL) decline compared to standard care during hospitalization for hematopoietic stem cell transplantation. 2. Patients treated...

Molecular markers associated with bone marrow clearance in AML and MDS

1. TP53 mutant status significantly associated with bone marrow blast clearance after treatment with decitabine in patients with acute myelogenous leukemia (AML) or myelodysplastic...

Palliative care likely to improve patient quality of life and reduce symptom burden

1. In this meta-analysis of randomized controlled trials, palliative care significantly improved patient quality of life and symptom burden, though bias and heterogeneity cast...

Palbociclib taken with letrozole increases progression-free survival in breast cancer patients

1. Patients with previously untreated estrogen receptor ER positive (ER+), human epidermal growth factor receptor 2 (HER2) negative breast cancer had longer progression-free survival...

Pembrolizumab associated improved survival for NSCLC compared to platinum-based chemotherapy

1. Progression free survival and overall survival was significantly increased in patients who received pembrolizumab vs. patients who received platinum-based chemotherapy. 2. Treatment related toxicities...
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