Oncology

Reports of high-impact oncology studies by medical professionals

Dietary supplementation with vitamin D and calcium not associated with reduced cancer risk in...

1. Vitamin D and calcium supplementation does not result in lower incidence of all-type cancer in post-menopausal women. Evidence Rating Level: 1 (Excellent) Study Rundown: With...

Pembrolizumab improves median survival amongst those with recurrent urothelial carcinoma

1. Patients with recurrent urothelial carcinoma experienced significantly longer median survival times when treated with pembrolizumab compared with chemotherapy agents.   2. Fewer treatment-related adverse events...

Imatinib safe and effective as long-term treatment for chronic myeloid leukemia: The IRIS trial

1. The efficacy of imatinib in chronic phase chronic myeloid leukemia (CML) persisted after 10-year follow-up. 2. No new significant adverse events related to imatinib...

Reminder devices may not improve medication adherence: The REMIND trial

1. In this randomized controlled trial, three low-cost reminder devices (pill bottle strip with toggles, digital timer cap, or standard pillbox) did not significantly...

Lower doses of radiation for pediatric cancers associated with fewer subsequent cancers

1. Over the past 40 years there has been a reduction in the average radiation doses given to children with certain cancers. Rates of...

Augmented adoptive cell transfer eradicates solid tumors [PreClinical]

  1. Combining tumor-specific T cells and pathogen-based immune stimulation, reenergized adoptive cell transfer (ReACT) targeted and eradicated tumor cells in mice. 2. ReACT led to...

Scalp cooling reduces alopecia among women undergoing chemotherapy for breast cancer

1. Less hair loss was observed in women who received scalp cooling prior to the start of adjuvant chemotherapy for early-stage breast cancer. 2. Improved...

Potential therapeutic target discovered for triple negative breast cancer [PreClinical]

1. Expression of the PIM1 protein was elevated in tumor samples from patients with MYC-positive triple negative breast cancer (TNBC), and was also associated...

Obesity leaves patients vulnerable to suboptimal end-of-life care

1. In this retrospective cohort, obesity was associated with reduced hospice use and in-home death during the last 6 months of life. 2. Higher Medicare...

Long-term users of e-cigarettes have decreased carcinogen and toxin levels compared to users of...

1. Former smokers who used only e-cigarettes or only nicotine replacement therapy (NRT) for ≥6 months (long-term) were found to have generally similar levels...
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