Oncology

Reports of high-impact oncology studies by medical professionals

Prognostic indicators for transarterial chemoembolization in patients with hepatocellular carcinoma with extrahepatic spread identified

1. In a retrospective study of 111 patients with hepatocellular carcinoma (HCC) with extrahepatic spread (EHS) treated with transarterial chemoembolization (TACE), median overall survival...

Wide surgical excision is effective in the treatment of subungual squamous cell carcinoma

1. In a retrospective review of 55 patients with subungal squamous cell carcinoma (SUSCC) without bone infiltration, wide surgical excision (WSE) followed by full-thickness...

Trends in thyroid cancer incidence and mortality in the United States from 1974-2013

1. This ecological study found that from 1974 to 2013, there were average annual increases in incidence rates and mortality rates in patients diagnosed...

Attenuation values may help differentiate renal neoplasm from simple cyst on contrast-enhanced CT

1. In a retrospective review of 125 patients with primary renal cell neoplasm that underwent computed tomography (CT), simple renal cysts were found to...

Multiple myeloma management with lenalidomide, bortezomib and dexamethasone associated with prolonged progression-free survival

1. The use of lenalidomide, bortezomib and dexamethasone (RVD) with transplantation was associated with a significantly longer progression-free survival compared to RVD therapy alone. 2....

Non-malignant extrapulmonary findings common in lung cancer screening program

1. In a retrospective review of over 17 000 patients in the National Lung Screening Trial (NLST), there was a high prevalence of potentially...

Laparoscopic hysterectomy equivalent to abdominal hysterectomy in disease-free and overall survival

1. Among women with stage I endometrial cancer, total laparoscopic hysterectomy compared to total abdominal hysterectomy resulted in equivalent disease-free survival at 4.5 years. 2....

Dietary supplementation with vitamin D and calcium not associated with reduced cancer risk in...

1. Vitamin D and calcium supplementation does not result in lower incidence of all-type cancer in post-menopausal women. Evidence Rating Level: 1 (Excellent) Study Rundown: With...

Pembrolizumab improves median survival amongst those with recurrent urothelial carcinoma

1. Patients with recurrent urothelial carcinoma experienced significantly longer median survival times when treated with pembrolizumab compared with chemotherapy agents.   2. Fewer treatment-related adverse events...

Imatinib safe and effective as long-term treatment for chronic myeloid leukemia: The IRIS trial

1. The efficacy of imatinib in chronic phase chronic myeloid leukemia (CML) persisted after 10-year follow-up. 2. No new significant adverse events related to imatinib...
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