Cardiology

Reports of high-impact cardiology studies by medical professionals

Antioxidant supplementation did not decrease risk of dementia in older asymptomatic men: The PREADViSE...

1. Based on this double-blind randomized, controlled trial which evolved into a cohort study, asymptomatic men taking vitamin E, selenium or a combination of...

Evolocumab demonstrated to have long-term efficacy at lowering low-density lipoprotiein: The Osler-1 trial

1. This multi-year, open-label extension of phase 2 trials examining the LDL-lowering efficacy of evolocumab (PCSK9-inhibitor) showed that evolocumab plus standard of care lipid...

Suboptimal dietary habits linked to deaths from heart disease, stroke, and type 2 diabetes

1. Over 45% of deaths due to heart disease, stroke, and type 2 diabetes in US adults in 2012 was due to suboptimal dietary...

Reminder devices may not improve medication adherence: The REMIND trial

1. In this randomized controlled trial, three low-cost reminder devices (pill bottle strip with toggles, digital timer cap, or standard pillbox) did not significantly...

No benefit of fibrinogen concentrate on intraoperative blood loss among patients undergoing high-risk cardiac...

1. Administration of fibrinogen concentrate in patients undergoing high-risk cardiac surgery did not significantly reduce intraoperative blood loss. Evidence Rating Level: 1 (Excellent) Study Rundown: Intraoperative...

No cardiac events in patients with pacemakers or ICDs who underwent MRI: The MagnaSafe...

1. This prospective cohort study of patients with cardiac pacemakers or implantable cardioverter-defibrillators (ICDs) undergoing magnetic resonance imaging (MRI) demonstrated no deaths, episodes of lead...

Maintenance program associated with reduced weight regain after weight loss

1. After 56 weeks of a weight maintenance intervention program, researchers found that mean weight regain in the intervention group (0.75 kg) was lower...

Polygenic index of waist-hip ratio associated with cardiovascular disease

1. Investigating a polygenic index of 48 single nucleotide polymorphisms for Waist-Hip Ratio adjusted for BMI, this study showed an association with increased biomarkers...

Inhibition of the immunoproteasome may improve graft acceptance [PreClinical]

  1. A targeted immunoproteasome inhibitor, DPLG3, was found to have high selectivity for the immune cell proteasome and was not toxic to other cell...

Intensive blood pressure control not linked with mobility/gait speed in elderly adults

1. In this secondary subgroup analysis of the Systolic Blood Pressure Intervention Trial (SPRINT), intensive blood pressure control (SBP<120mmHg) in adults over the age...
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