Cardiology

Reports of high-impact cardiology studies by medical professionals

Pravastatin therapy for primary prevention in the elderly did not reduce mortality

1. In this post-hoc analysis of the Lipid-Lowering Trial (LLT) component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT) randomized...

No beneficial effects of oral iron repletion in patients with heart failure and iron...

1. Oral iron repletion did not improve exercise capacity as measured by peak oxygen uptake (VO2). 2. There were no significant effects from oral iron...

Data support targeted approach to cholesterol screening in young adults

1. In the absence of risk factors, there was low prevalence of increased ASCVD risk in women under 50 and men under 40. 2. Only...

PCSK9 inhibitor significantly reduces the risk of cardiovascular events: The FOURIER trial

1. In addition to significantly lowering levels of low density lipoprotein cholesterol (LDL-C), evolocumab reduced the composite risk of cardiovascular events in atherosclerotic patients...

A routine invasive strategy may significantly reduce death risk in unstable angina

1. Routine invasive coronary angiography was associated with a reduction in 12-month mortality in patients with unstable angina. 2. The survival benefit of invasive coronary...

Dabigatran linked to fewer major bleeding events than warfarin in ablation: The RE-CIRCUIT trial

1. The incidence of major bleeding events up to 8 weeks after catheter-directed atrial fibrillation ablation was significantly lower in those receiving continuous therapy...

Using HEART score to risk stratify patients with chest pain is safe but underutilized...

1. The findings of this cluster randomized trial suggest that it is safe to use the HEART score during initial assessment of chest pain...

Mixed cardiovascular benefit with PCSK9 inhibitior bococizumab: The SPIRE trial

1. When added to statin therapy, the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor bococizumab significantly reduced the risk of cardiovascular events in patients...

High-sensitivity troponin T result may help rule out of myocardial infarction

1. In this meta-analysis, researchers found that a high-sensitivity cardiac troponin T (hs-cTnT) assay along with a nonischemic electrocardiogram (ECG) could be used to...

Midlife vascular risk factors linked with higher brain amyloid in later life

1. In this prospective cohort study, the presence of vascular risk factors during midlife were associated with higher brain amyloid in later life. 2. Higher...
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