Multicomponent intervention linked to improved guideline adherence in long-term opioid therapy

1. In this cluster-randomized trial targeting primary care clinicians (PCC) treating patients with long-term opioid therapy in safety-net practices, a multicomponent intervention increased guideline...

As incidence of pediatric ATV-related injuries decreases, mortality remains stable

1. While the mean incidence of all-terrain vehicle (ATV)-related injuries in children <18 years decreased from 2009-2014 as compared to 2004-2008, the mean mortality...

Demand for FMT likely to increase with rise in multiply recurrent C. difficile cases

1. Multiply recurrent Clostridium difficile infection (mrCDI) incidence has increased disproportionately to Clostridium difficile infection (CDI), independent of known risk factors for CDI. 2. There is...

Cardiovascular testing after emergency department presentation may not reduce risk of myocardial infarction

1. Based on this retrospective cohort study, noninvasive testing done within 30 days of patient presentation with chest pain at the emergency department reduced...

Older adults receiving recombinant influenza vaccine better protected against influenza

1. Older adults receiving recombinant influenza vaccine experienced fewer cases of polymerase chain reaction (PCR) confirmed influenza-like illness than patients receiving a similar inactivated...

Small and very small unruptured intracranial aneurysms may have little risk for rupture

1. Poor-quality evidence suggests unruptured intracranial aneurysms have low growth and rupture rates. 2. Very small unruptured intracranial aneurysms are associated with little or no...

Clinical scale, clinician suspicion poorly predict serious infections

1. In a prospective study of febrile full term infants 60 or fewer days old, neither the Yale Observation Scale (YOS) score nor unstructured...

Variation in markup of charges in emergency department and internal medicine services

  1. Based on this retrospective cohort analysis, there is substantial variation in markup of charges across the United States for services performed for uninsured...

Delays in surgical intervention do not increase odds of appendiceal perforation

1. Time from initial emergency department evaluation to appendectomy onset was not associated with increased odds of appendiceal perforation (AP). 2. Increased perforation risk was...

Structured protocol adherence linked to improved efficiency and favorable outcomes in stroke at stroke...

1. Adherence to a structured protocol improved efficiency in time to mechanical thrombectomy for patients with suspected large-vessel occlusion stroke presenting to a primary...
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