Infectious Disease

Reports of high-impact infectious disease studies by medical professionals

Pritelivir reduces HSV-2 positive swabs in those with multiple recurrences

1. In this randomized controlled trial, pritelivir was effective in reducing the number of HSV-2 positive swabs, total days with herpetic lesions, and the...

Shorter courses of antibiotics for otitis media less effective in children

1. Reducing the duration of antibiotic treatment for acute otitis media (AOM) in children aged 6-23 months was associated with a higher rate of...

Dry cord care non-inferior to antiseptic care

1. In this cluster-randomized, 2-period crossover trial, omphalitis occurred in 0.07% of newborns randomized to dry umbilical cord care compared to 0% in those...

Adverse neurologic outcomes associated with maternal Zika virus infection

1. Infants born to symptomatic Zika-positive mothers demonstrated higher rates of fetal death, fetal growth restriction and central nervous system abnormalities. 2. Zika-positive pregnant women...

Announcements improve HPV vaccination over conversations

1. Physicians who used an announcement technique when introducing human papillomavirus (HPV) vaccination had a higher rate of vaccination coverage compared to other techniques. 2....

Dapivirine-containing vaginal ring linked to reduced HIV-1 transmission

1. In a randomized, placebo-controlled trial of sexually active women in sub-Saharan Africa, dapivirine-containing vaginal rings were linked with a significantly reduced incidence of...

Low volume status linked to adverse outcomes in shiga-toxin producing Eschericia coli illness

1. Based on a systematic review and meta-analysis, low volume status (as estimated with clinical judgement or hematocrit values) in children presenting with shiga-toxin...

Antibody decreases Zika virus levels and fetal transmission [PreClinical]

1. Antibodies were isolated from patients with prior Zika virus infection and one specific antibody, ZIKV-117, decreased fetal transmission of Zika virus as well...

GeoSentinel analysis of clinical manifestations and complications related to Zika virus disease

1. Exanthema, fever, and arthralgia comprise the most common symptoms of Zika virus disease. 2. Considerable risk for major complications exists with first trimester transmission...

Ledipasvir-sofosbuvir may be safe treatment for kidney transplant recipients with chronic HCV

1. Ledipasvir-sofosbuvir treatment was associated with rapid chronic hepatitis C (HCV) RNA suppression. 2. Ledipasvir-sofosbuvir treatment was generally well tolerated in kidney transplant patients. Evidence Rating...
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