Inaxaplin reduces proteinuria in focal segmental glomerulosclerosis with two APOL1 variants
1. In preclinical studies, inaxaplin selectively inhibited apolipoprotein L1 (APOL1) in vitro and reduced proteinuria in a APOL1 G2-homologous transgenic...
1. In preclinical studies, inaxaplin selectively inhibited apolipoprotein L1 (APOL1) in vitro and reduced proteinuria in a APOL1 G2-homologous transgenic...
1. This randomized control trial found that febuxostat has a reno-protective effect that can reduce the incidence of contrast-induced acute...
1. In this randomized controlled trial, among patients with recurrent kidney stones, hydrochlorothiazide did not alter the risk of symptomatic...
1. Disease-free survival in the placebo group was 50.7 months and was never reached in the intervention group; however, there...
1. Risk of major adverse cardiac events increased amongst patients with a specific glomerular disease, including non-proliferative glomerulopathy, renal vascular...
1. The mean eGFR slope was comparable among patients allocated to sodium bicarbonate and placebo over 24 months. 2. Sodium...
1. In this patient-level pooled analysis of 3 randomized clinical trials, among 506 patients with hypertension, a greater reduction in...
1. In this sham-controlled, randomized clinical trial, among 224 patients with hypertension, ultrasound renal denervation demonstrated clinically relevant reductions in...
1. Time-to-discharge-alive from the hospital was similar among both high- and regular-protein groups. 2. There was no significant inter-group difference...
1. In this randomized controlled trial, machine perfusion of the kidney reduced delayed graft function compared to therapeutic hypothermia. 2....
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