Neurology

Reports of high-impact neurology studies by medical professionals

No difference between placebo, amitriptyline and topiramate in reducing pediatric migraine: The CHAMP trial

1. In this study, no significant intergroup differences between amitriptyline, topiramate and placebo for reduction in total number of headache days was observed. 2. Amitriptyline...

Triple therapy with rivaroxaban reduces bleeding compared to warfarin: The PIONEER AF-PCI trial

1. In patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI), treatment with rivaroxaban, in addition to dual antiplatelet therapy (DAPT), led...

Induced hypothermia not associated with improved outcomes for status epilepticus: The HYBERNATUS study

1. Absence of functional impairment 90 days after status epilepticus (SE) was, non-significantly, higher in patients that received standard care compared to patients in...

Policies that expand patient access to multiple health systems may compromise patient safety

1. Higher rates of potentially unsafe medication (PUM) prescribing were associated with veterans with dementia using dual healthcare systems. 2. Dual users were exposed to...

Long-term collaborative care and occupational therapy did not slow functional decline in patients with...

1. Regardless of treatment intervention, all patients had progressive functional decline. 2. No statistically significant difference was observed in Activity of Daily Living Scale (ADL)...

Children with persistent post-concussion symptoms have a lower quality of life

1. Based on a prospective, multicenter cohort study conducted in Canada, children after a concussion who had persistent post-concussion symptoms scored lower on a...

Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke

1. Compared to patients treated with medical therapy alone, patients with an ischemic stroke undergoing endovascular thrombectomy combined with medical therapy had lower rates...

Decompressive craniectomy linked with decreased mortality in TBI: The RESCUEicp trial

1. Patients with traumatic brain injury (TBI) and refractory intracranial hypertension following 2 stages of standard therapy who were then randomized to receive decompressive...

No difference in mortality for intensive versus standard reduction in blood pressure in intracerebral...

1. There were no significant differences in the proportion of death and disability in patients with intracranial hemorrhage with blood pressures maintained at 140-179...

Endovascular therapy may be effective in large vessel occlusion of M2 segment

1. Endovascular therapy after acute ischemic stroke of large vessel occlusion of M2 segment of the middle cerebral artery (MCA) was associated with better...
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