Neurology

Reports of high-impact neurology studies by medical professionals

Late-life mentally stimulating activities may decrease risk of mild cognitive impairment

1. This prospective cohort study showed that mentally stimulating activities (computer use, craft activities, social activities and playing games) in late-age (>70 years old)...

Researchers validate scoring of postconcussive symptom measure to characterize duration 

1. After analyzing multiple approaches to the Postconcussion Symptom Inventory (PCSI), researchers found that an increase in severity on 2 or more PCSI items...

Ocrelizumab decreases multiple sclerosis relapse rate compared to interferon beta-1a

1. Patients with multiple sclerosis (MS) treated with ocrelizumab experienced lower annualized relapse rates compared to those treated with interferon beta-1a over a 96-month...

Ocrelizumab associated with lower progression rates for primary progressive multiple sclerosis: The ORATORIO trial

1. A significant decrease in the rate of clinical and MRI progression was observed for Primary progressive multiple sclerosis (PPMS) patients that received ocrelizumab. 2....

Asymptomatic women at high risk for Multiple Sclerosis may have early subclinical neuroimaging abnormalities

1. Women at higher risk for multiple sclerosis (MS) (based on family history, genetic testing, blood biomarkers, etc.) had significantly more early imaging and...

No difference between placebo, amitriptyline and topiramate in reducing pediatric migraine: The CHAMP trial

1. In this study, no significant intergroup differences between amitriptyline, topiramate and placebo for reduction in total number of headache days was observed. 2. Amitriptyline...

Protein therapy combined with stem cell transplantation repairs stroke-induced brain damage [PreClinical]

  1. Neural stem cell (NSC) transplantation and subsequent treatment with a variant of activated protein C (3K3A-APC) improved engraftment success and motor skills in...

Triple therapy with rivaroxaban reduces bleeding compared to warfarin: The PIONEER AF-PCI trial

1. In patients with atrial fibrillation (AF) who undergo percutaneous coronary intervention (PCI), treatment with rivaroxaban, in addition to dual antiplatelet therapy (DAPT), led...

Induced hypothermia not associated with improved outcomes for status epilepticus: The HYBERNATUS study

1. Absence of functional impairment 90 days after status epilepticus (SE) was, non-significantly, higher in patients that received standard care compared to patients in...

Policies that expand patient access to multiple health systems may compromise patient safety

1. Higher rates of potentially unsafe medication (PUM) prescribing were associated with veterans with dementia using dual healthcare systems. 2. Dual users were exposed to...
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