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The Classics in Medicine™: Summaries of the Landmark Trials | Search Directory

...such as The Classics in Cardiology™ , Classics in Radiology™ , etc. Over 500 landmark trial summaries included! Support the The Classics Series™ by buying the paperback or e-book editions: The Classics in Medicine™ (First Ed., ISBN 978-0996304290) The Classics in Radiology™ (First Ed. ISBN 978-0996304283) All content © 2021 2 Minute Medicine, Inc. | Boston, MA | Main Directory Unlimited Reading for Subscribers | Need Group Access? Email info@2min...

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...diabetes-related morbidity and mortality“,”The Lancet, 1998\nBMJ, 1998″,”20000″,”1.\tFor patients with type 2 diabetes mellitus, pharmacologic blood glucose control with sulfonylureas or insulin significantly reduces the risk of microvascular complications, but not macrovascular complications\n2.\tMetformin therapy is associated with significant reductions in diabetes-related and all-cause mortality; thus, it is considered first-line therapy for...

Patient Basics: Swimmer’s Ear (Otitis Externa)

...ph nodes near the ear In rare cases, a culture of the drainage is necessary. For a culture, a sample of the draining fluid is treated in a laboratory to see what bacteria or fungi grow. Your doctor also may examine the eardrum to look for signs of middle ear infection. Expected Duration With treatment, symptoms usually improve within 1 to 3 days and go away completely in 7 to 10 days. The problem can return, especially if you don’t take steps to p...

2 Minute Medicine Rewind December 7, 2020

...in London, Ontario with a self-reported pain score of at least 40 mm on a 100 mm visual analogue scale (mean pain score was 60±18 mm for HBB, and 62±17 mm for acetaminophen). The primary outcome was pain score 80 minutes after administering the analgesic, to reflect the drugs’ peak action. Overall, the results showed no difference in pain score: For HBB, the mean score was 29±26 mm, while for acetaminophen, it was 30±29 mm. The adjusted difference...

2 Minute Medicine Rewind September 6, 2021

...l dysfunctions (n=21 [35.6%] vs n=3450 [23.8%]; odds ratio, 1.77; 95% CI, 1.04-3.02). Furthermore, sepsis patients were at higher risk of postpartum hemorrhage, maternal ICU admissions, and preeclampsia compared to their non septic counterparts. As previously mentioned, prior studies have focused primarily on immediate maternal morbidity and mortality. Therefore, a strength of this study was its focus on obstetric and postpartum health as well as...

Patient Basics: Earache

...ticularly if the infant drinks from a bottle while lying on his or her back. For this reason, it is better to hold the baby at least semi-erect during feeding. Children are more prone to earaches if they: Have had ear infections before their first birthday Are frequently exposed to cigarette smoke Have a family history of ear infections Stay in day care Were born premature or at low birth weight Are male (boys have more middle ear infections than...

2 Minute Medicine Rewind October 12, 2020

...h 36 deaths in the intervention and 45 deaths in the placebo (hazard ratio 0.81, 95% CI 0.59 to 1.11, p = 0.18). With regards to safety, there was no difference in arterial thrombotic complications and myocardial infarction, although 8 adverse events occurred in the treatment group, compared to 21 in the placebo group. In some cases, 30-day mortality was lowered in the treatment compared to the placebo, such as when 2 g of additional tranexamic ac...

2 Minute Medicine Rewind July 27, 2020

...over the years, increasing six-fold in the United States between 1975 and 2001. Currently, Barrett’s Esophagus (BE) is the sole known lesion to be a precursor for EAC, and factors such as for obesity, use of tobacco, and gastroesophageal reflux disease (GERD) have been identified as associated risk factors. Currently however, the association between tonsillectomy and development of EAC is not well characterized, despite these procedures being rela...

2 Minute Medicine Rewind June 28, 2021

...ndividuals qualified for shielding, 2.9% received a diagnosis of COVID-19, 0.2% entered critical care, and 0.7% died. When compared to the no risk category, the severe COVID-19 rate ratio was 3.21 (95% CI 3.01-3.41, p < 0.001) for moderate risk and 6.3 (95% CI 5.8-6.8, p < 0.001) for very high risk (shielding eligible) patients. Within the shielding category, solid organ transplant patients were at the great risk, with a rate ratio of 13.4 (95% CI...

Patient Basics: Hearing Loss in Adults

...ative effects of aging on the ears. Hearing loss usually begins after age 60. Both ears are affected. It is typically harder to hear high-pitched tones (women’s voices, violins) than low-pitched ones (men’s voices, bass guitar). Hearing loss usually occurs gradually over a period of years. The person may not realize that he or she has difficulty hearing. Other causes — There are more than 100 different causes of hearing loss in adults. The most co...

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