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classics.csv

...rally well tolerated, with common complaints including dizziness, leg edema, and coughing.”],[“The CARE trial: Statins in coronary artery disease“,”NEJM, 1996″,”6321″,”1.\tCholesterol-lowering therapy with statins reduces the risk of coronary events and stroke in patients with previous coronary artery disease and low-density lipoprotein levels >125 mg/dL\n2.\tThe reduction in coronary events with statin therapy was greater in women and patients wi...

The Classics in Medicine™: Summaries of the Landmark Trials | Search Directory

...r Subscribers | Need Group Access? Email info@2minutemedicine.com Use the real-time search box below to filter trials instantly by disease, drug, name, etc. (try “warfarin”) [table id=4 /]...

2 Minute Medicine Rewind September 20, 2021

...an insertion of a peripheral intravenous catheter (PVC). A rare, but severe, complication of this procedure is PVC-associated bloodstream infections (PVC-BSIs). The US Centre for Disease Control does not have a recommendation for whether PVCs should be replaced routinely, or replaced only when clinically indicated: A recent systematic review found no difference in catheter-associated BSIs, but only 3 PVC-BSIs occurred in all of the studies. Theref...

2 Minute Medicine Rewind September 6, 2021

...restriction leading to small for gestational age, stillbirth, preeclampsia, and deficient amniotic fluid levels. These outcomes were compared between the sepsis group and the reference group. Overall, of the 14565 patients, n= 59 had antenatal sepsis with the most common causes coming from urinary tract and pulmonary infections. Individuals who had experienced antepartum sepsis hospitalisations had twice the risk of placental dysfunctions (n=21 [...

2 Minute Medicine Rewind Jan 25, 2021

...t in health behaviours towards a sedentary lifestyle, poor dietary patterns, and increased screen time. Less is known about the impact of blood pressure and/or weight, specifically fat distribution, on retinal microvasculature at a younger age. In this ongoing population-based cohort study, as a subset of the Hong Kong Children Eye Study, 1006 children aged 6 to 8 years underwent full ophthalmic and physical examinations as well as standardized in...

2 Minute Medicine Rewind October 4, 2021

...onsequences including chronic hepatic inflammation, cirrhosis, liver cancer, and death. Previous studies have found that First Nations people in Canada are disproportionately affected by HCV infection. This retrospective matched cohort study aimed to calculate total and net costs per 30 days of HCV infection in First Nations communities. Health administrative databases were used to gather information from 2004-2014 on Status First Nation people ha...

2 Minute Medicine Rewind March 1, 2021

...or iron deficiency in patients newly diagnosed with HF and during follow-up, and only recommends intravenous iron supplementation for patients with HF with reduced ejection fraction (HFrEF) diagnosed with ID. However, little is known about how these guidelines are implemented in clinical practice. In this French observational, transversal multicentre trial, data from 2822 patients, who were hospitalized at least once for HF in the last five years...

2 Minute Medicine Rewind October 18, 2021

...t, causing significant pain, reducing physical function and quality of life, and increasing risk of all-cause mortality. From paracetamol (acetaminophen) to topical or oral non-steroidal anti-inflammatory drugs (NSAIDs) to opioids, clinicians have a myriad of options when prescribing pharmacotherapy for OA, making clinical decisions especially challenging. Research suggests that improvements in pain and physical function are similar for NSAIDs and...

2 Minute Medicine Rewind June 14, 2021

...el: 2 (Good) Postpartum mental illness affects approximately 1 in 5 mothers, and can present as anxiety, depression, bipolar disorder, psychotic disorders, alcohol and or substance abuse. This emotional burden on mothers also represents a clinical burden on the health care system with increasing rates due to the COVID-19 pandemic. This study aimed to better understand the extent of this exasperation by comparing pre and current pandemic data. In t...

2 Minute Medicine Rewind January 11, 2021

...solute risk were viral pneumonia, respiratory failure, acute kidney failure, and sepsis. 2. Complications highly associated with COVID-19 with low absolute risk were myocarditis, pneumothorax, and disseminated intravascular coagulation. Evidence Rating Level: 2 (Good) During the COVID-19 pandemic, greater than 50 million individuals worldwide have been diagnosed with the disease. Although most people present with mild or no symptoms, 20% of patien...

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