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...service contained therein. Advertising Disclosure: We are a for profit website site that may receive compensation from the companies who place advertisements or affiliate links on 2minutemedicine.com. We also use third party advertisements on 2minutemedicine.com to support our site. Some of these advertisers may use technology such as cookies and web beacons when they advertise on our site, which will also send these advertisers (such as Google t...

Quick Take: Randomized Phase II Trial Comparing Site-Specific Treatment Based on Gene Expression Profiling...

...empirical treatment, although this study was limited in that there was an imbalance in predicted tumor types between the two arms. Stratification based on predicted tumor types may also be useful in future studies. Click to read the study in JCO Image: PD ©2019 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be con...

Coronary angioplasty safe and effective at facilities without on-site cardiothoracic surgery

...otal of 24,387 patients at 59 VA facilities underwent PCI between October 2007 and September 2010. 6,616 patients underwent PCI at facilities without on-site CT surgery and 17,771 at facilities with on-site CT surgery. Patients undergoing PCI at facilities without on-site CT surgery had lower rates of past MI, cardiac risk factors, and non-cardiac co-morbidities as well as higher rates of high-risk (Type C) stenosis and CTO. These patients (40.2%)...

Nonemergent percutaneous coronary intervention safe without on-site cardiac surgery services

...n-site cardiac surgery, compared to 9.4% with on-site cardiac surgery (p<0.001 for noninferiority). The MACE rates at 12 months were 17.3% vs 17.8% (p<0.001 for noninferiority). Additionally, angiographic review showed no difference in procedural success rates between cohorts. Outcomes varied among hospitals, with median odds of 1.3 at 12 months– suggesting MACE may be 1.3 times as likely at one facility compared to another. The median odd was 1.5...

2 Minute Medicine Rewind January 21, 2019

...no associated increase in risk of dyslipidemia (aHR 0.87, 95% CI 0.75 to 1.00). The risk of cardiometabolic disorders was greater in males (aHR 2.13, 95% CI 2.01 to 2.26) than in females (aHR 1.79, 95% CI 1.64 to 1.96). The cumulative incidence of any cardiometabolic disorder was 52.5% for individuals with TS or CTD (95% CI 47.7% to 57.4%) in comparison to 29.5% for the general population (95% CI 29.3% to 29.6%). In terms of antipsychotic use, inv...

Single-site robotic cholecystectomy is safe, but technically challenging

...traditional approaches. 2. Following single-site robotic cholecystectomy, 11.6% of patients required hospital admission and 6.3% required readmission. 3. 24% of patients suffered cholecystotomy during dissection, but without any measurable sequelae. Evidence Rating Level: 2 (Good) Study Rundown: This study demonstrated the feasibility and comparable safety profile seen with single-site robotic cholecystectomy (SSRC) versus traditional laparoscopi...

Patient Basics: Head Injury In Children

...al Info National Institute of Neurological Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Phone: 301-496-5751 Toll-Free: 1-800-352-9424 TTY: 301-468-5981 http://www.ninds.nih.gov/ National Institute of Child Health & Human Development Building 31, Room 2A32 MSC 2425 31 Center Drive Bethesda, MD 20892-2425 Toll-Free: 1-800-370-2943Fax: 301-496-7101 http://www.nichd.nih.gov/ American Academy of Neurology (AAN) 1080 Montreal Ave. St. Paul, MN...

Patient Basics: Head Injury In Adults

...illion emergency department visits in the United States, with more than 72,000 deaths. An additional 80,000 to 210,000 people with moderate or severe head injuries become disabled or require extended hospital care. Overall, traumatic head injuries are the most common cause of death among Americans aged 45 and younger. In addition, head injuries resulting from falls are a very common cause of hospitalization and death among people older than 75. Me...

Patient Basics: Soft Tissue Sarcoma

...ductive organs. In most cases, rhabdomyosarcoma affects children under age 10. Less often, it affects teenagers. The disease is rare in adults. Under the microscope, rhabdomyosarcoma tumor cells look like primitive muscle, similar to the immature muscle cells of a developing fetus. There are two main types of rhabdomyosarcoma: embryonal and alveolar. In general, embryonal rhabdomyosarcoma tends to be localized; it rarely spreads (metastasizes) awa...

2 Minute Medicine Rewind March 8, 2021

...ACs, after a bleeding event related to OAC use. Data was gathered between 2012 and 2017 from patients aged 66 years and older, who had a hospital admission related to bleeding, and a prescription for an OAC within 100 days prior to admission. Of the 6793 patients in the study, 70.5% of patients resumed using an OAC within a year of admission (71.6% for GI bleed, and 45.6% for intracranial hemorrhage). For all categories of bleed, there was a lower...

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