Inhibiting cholesterol uptake decreases growth of pancreatic tumors [PreClinical]
1. Metabolic profiling of cells from mice bearing spontaneous pancreatic ductal adenocarcinoma (PDAC) revealed high upregulation of genes relating to...
1. Metabolic profiling of cells from mice bearing spontaneous pancreatic ductal adenocarcinoma (PDAC) revealed high upregulation of genes relating to...
1. Genetically or pharmacologically blocking the tyrosine phosphatase receptor σ (PTPσ) in mice following myocardial infarction (MI) resulted in increased...
1. Tuberculosis (TB) granulomas exhibited similar properties to solid cancerous tumors, characterized as dense tissue masses with abnormal blood vessel...
1. Endostatin (ES), a drug commonly studied and applied for its inhibition of tumor blood vessel growth (termed angiogenesis), decreased...
1. Administration of oxytocin to a monogenic mouse model of autism improved social interactions 2. Oxytocin treatment during the developmental...
1. Following a chemical library screen, the compound 4-hydroxyacetophenone (4-HAP) was found to target mechanical changes in cell shape important...
1. The newly discovered antibacterial compound teixobactin, isolated from the soil bacteria Eleftheria terrae, targeted cell wall synthesis in gram-positive...
1. Germline transmission of a mutation in ETV6 was identified in three distinct families presenting with myelodysplastic syndrome (thrombocytopenia and...
1. Two near-infrared fluorophores (NIRfs), fluorescing at different wavelengths, were identified for their inherent chemical affinity for thyroid tissue. 2....
1. In response to infection by Staphylococcus aureus (S. aureus), dermal cell populations expanded and differentiated into adipocytes. 2. This...
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