Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

[BMJ] In patients with new diabetes, blood pressure below 130/80 mm Hg not associated...

Image: CC/Deutsche Fotothek  There have been many studies assessing the role of blood pressure (BP) control and mortality in diabetes - the United Kingdom Prospective...

[BMJ] Low glycemic index diet in pregnancy has positive effect on gestational weight gain...

Image: CC/Ernest Large for gestational age infants (macrosomia) pose problems for both the neonate and the mother. These infants are more likely to become obese...

[NEJM] Reduction in growth by inhaled glucocorticoids in children found to persist into adulthood

Image: Budesonide, GNU FDL Primer: Inhaled glucocorticoids, a key in the treatment of persistent asthma in children, are known to reduce growth velocity in a...

[NEJM] Tiotropium a significant boost for poorly controlled asthmatics on inhaled glucocorticoids and beta-agonists

Image: Tiotropium - CC/BenWeber. Trial info: Supported by Boehringer Ingelheim and Pfizer. ClinicalTrials.gov numbers, NCT00772538 and NCT00776984. Primer: Exacerbations in asthmatics may persist despite treatment with...

[JAMA] Association of changes in clinical characteristics and management with improvement in survival among...

Image: CC/GFDL. ST segment elevation in Leads II, III and aVF for an inferior acute myocardial infarction Primer: Over the past decade we have seen decreases...

[Arch Intern Med.] Common environmental exposure linked to cardiovascular disease

Image: CC.  Primer: Recent evidence suggests the typical risk factors – smoking, obesity, and genetics – in cardiovascular disease (CVD) leave a portion of cases...

[BMJ] Kidney stones associated with increased risk of end-stage renal disease

Image: CC/James Heilman. Stone in kidney (arrow), CT scan.  Primer: Kidney stones are a commonly encountered clinical problem, and while there is limited evidence linking...

[THE LANCET] Severe chronic kidney disease patients have higher coronary risk than diabetics. Time...

Image: CC/PD. Enlarged kidney (drawing).  Primer: Coronary heart disease (CHD) “equivalent”, a term used to describe some trait or factor that results in a 10-year risk...

[NEJM] No difference in survival between intermittent androgen deprivation therapy and continuous therapy for...

Image: CC/EAS. Human PSA.  Primer: Androgen deprivation therapy is the cornerstone for metastatic prostate disease. Intermittent therapy, essentially cycles of androgen deprivation followed by exposure...

[JAMA] Risk of malignancies in patients with rheumatoid arthritis treated with biologic therapy: a...

Image: CC/Martin Steinhoff. Arthritis of the interphalangeal joints. Primer: In certain rheumatoid arthritis (RA) patients, treatment with typical disease-modifying anti-rheumatic drugs (DMARDs), including methotrexate, may...

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