Evening-dose immune checkpoint inhibitors were associated with worse survival outcomes
1. Receiving at least 20% of infusions after 1630h was associated with decreased overall survival in patients treated with immune-checkpoint...
Dermatology
Belimumab after rituximab reduces risk for severe flare in systemic lupus erythematosus
1. Belimumab combined with rituximab was shown to significantly reduce IgG anti-dsDNA antibody levels in patients with systemic lupus erythematosus....
Phototherapy not associated with increased risk of childhood cancer
1. In a large cohort, phototherapy for neonatal hyperbilirubinemia is not associated with any childhood cancer. Evidence Rating Level: 2...
Incidence of keratinocyte carcinoma disproportionately rising for young females over past two decades r
Incidence and mortality rates of keratinocyte carcinoma from 1998-2017: A population-based study of sex differences in Ontario, Canada 1. The...
Novel macrophage-regulating cream demonstrated superior therapeutic efficacy for the treatment of diabetic foot ulcers compared to standard absorbent dressing
1. Topical application of ON101, a macrophage regulator cream, demonstrated superior therapeutic efficacy in the treatment of diabetic foot ulcers...
Severe atopic dermatitis associated with symptoms of depression and internalizing behaviors in children
1. The findings of this longitudinal cohort study suggest an association between atopic dermatitis and symptoms of depression and internalizing...
Rituximab increases sustained complete remission in patients with pemphigus vulgaris
1. A higher sustained complete remission rate was shown with rituximab treatment compared to mycophenolate mofetil in patients with pemphigus...
Epidemiologic analysis of chilblains cohorts before and during the COVID-19 pandemic
1. The incidence of chilblains increased during the COVID-19 pandemic, but chilblains cases were only weakly associated with COVID-19 infection,...
Upadacitinib plus topical corticosteroids is safe and effective for moderate-to-severe atopic dermatitis
1. Upadacitinib combined with topical corticosteroids reduced Eczema Area and Severity Index (EASI) and Investigator’s Global Assessment for atopic dermatitis...
Upadacitinib monotherapy is effective for patients with moderate-to-severe atopic dermatitis
1. The proportion of patients with EASI ≥75% was significantly greater in the upadacitinib 30 mg and 15 mg groups...
Popular Reports
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Peripherally inserted central catheters are associated with twice as many complications than midline catheters when used short-term
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Capecitabine + oxaliplatin chemoradiotherapy does not increase survival, but increases toxicity, compared to capecitabine alone in the postoperative treatment of rectal cancer
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Ultrasound features associated with shoulder complaints
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Automated pupillometry may be helpful in opioid agonist therapy dosing for opioid use disorder
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The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]
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