Discontinuation of statins in older patients with polypharmacy associated with increased cardiovascular events

1. Older patients with polypharmacy who discontinued statins had increased rates of admissions for heart failure, all-cause emergency hospital admissions, cardiovascular outcomes, and all-cause...

Prophylactic anticoagulation associated with lower in-hospital and 60-day mortality for patients hospitalized with COVID-19

1. For patients hospitalized with COVID-19, both prophylactic- and treatment-dose anticoagulation were associated with lower in-hospital mortality compared with no anticoagulation. 2. However, given that...

Multisystem inflammatory syndrome in children remains a rare but serious complication associated with SARS-CoV-2...

1. In this cohort study, multisystem inflammatory syndrome in children was a rare but serious complication associated with SARS-CoV-2 infection. 2. The findings of increased...

Direct to angiography in transferred patients with large vessel occlusion stroke associated with faster...

1. Transferred patients with a large vessel occlusion stroke undergoing endovascular thrombectomy may have faster treatment and improved outcomes from a direct to angiography...

Intravenous eptinezumab associated with a more rapid onset and prolongation of symptom relief from...

1. Intravenous eptinezumab-treated participants achieved significantly earlier freedom from headaches and from their most bothersome symptoms compared to placebo in those suffering from an...

Rapid respiratory pathogen testing does not significantly alter antibiotic prescription rates among children with...

1. When treating children with an acute respiratory illness in the emergency department, no significant difference in antibiotic prescription rates was observed when clinicians...

Carriers of genetic variants of inherited cardiomyopathies and arrhythmias associated with unexplained sudden cardiac...

1. In this study of White and African American adults who had unexplained sudden cardiac death, nearly 20% of individuals had pathogenic or likely...

Net fluid balance not associated with hospital readmission rates among sepsis patients

1. There was no association found between positive fluid balance at the time of discharge and readmission at 30 days post-discharge in non-critically ill...

Dexamethasone vs methylprednisolone high dose for COVID-19 pneumonia

1. Hospitalized COVID-19 patients receiving high-dose methylprednisolone followed by oral prednisone had improved clinical outcomes compared to patients receiving dexamethasone. Evidence Rating Level: 2 (Good) In...

Continuous infusion of hypertonic saline following traumatic brain injury does not improve neurological outcomes...

1. No significant difference was found in neurological function recovery measured by extended Glasgow scale score in patients with moderate to severe traumatic brain...

All-time hits