Unrecognized myocardial infarctions associated with embolic cerebral infarctions of undetermined source

1. In this cross-sectional cohort study of older adults in Iceland, MRI findings of myocardial infarction was associated with coincident MRI findings of cerebral...

Quick Take: Treatment and Long-Term Clinical Outcomes of Incidental Pulmonary Embolism in Patients With...

Venous thromboembolism (VTE) is a common complication in patients with cancer. Often, VTEs are incidentally detected on imaging studies undertaken for cancer staging or...

Ambulatory rhythm monitoring detects heart block after transcatheter aortic valve replacement

1. The routine use of ambulatory event monitoring (AEM) commonly detects high grade atrioventricular block (H-AVB) after discharge following Transcatheter Aortic Valve Replacement (TAVR). 2....

Rate of opioid prescribing in adolescents largely unchanged

1. Between 2005 and 2015, there was a small decrease in the rate of opioid prescriptions in emergency department (ED) visits to adolescents and...

Use of aspirin for primary prevention linked to increased risk of intracranial hemorrhage

1. In this systematic review and meta-analysis, use of low-dose aspirin in patients without symptomatic cardiovascular disease was linked with an increased risk of...

Sodium-glucose cotransporter-2 inhibitors may be linked to Fournier gangrene

1. In this descriptive case series, 55 cases of patients with diabetes who developed Fournier gangrene while using sodium-glucose cotransporter-2 (SGLT2) inhibitors are described. 2....

The EXTEND trial: neurological deficits decreased with thrombolysis up to 9 hours after stroke...

1. Patients presenting between 4.5 and 9 hours after stroke onset with viable brain tissue who received thrombolytic therapy had better neurological outcomes compared...

Patent foramen ovale associated with four-fold increased risk for ischemic stroke in patients with...

1. In this prospective cohort study, patients with symptomatic pulmonary embolism (PE) and a patent foramen ovale (PFO) were found to have a significantly...

The PRISM trial: Progesterone therapy does not alter birth outcomes in women with early...

1. Women with early pregnancy bleeding administered progesterone experienced similar rates of live births occurring after 34 weeks’ gestation as women treated with placebo. 2....

Ticagrelor reversal agent provides immediate and sustained effect

1. A monoclonal antibody fragment to ticagrelor, PB2452, increased platelet function significantly in healthy patients given the oral P2Y12 inhibitor ticagrelor. 2. Adverse effects were...
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