Centralized stroke care linked to improved mortality and reduced length of stay

1. In this study, specialized inpatient care of stroke patients was linked to better clinical outcomes.  2. Centralization of stroke care was also linked to...

Early alteplase treatment leads to better stroke outcomes regardless of age or stroke severity

1. Alteplase (recombinant tissue plasminogen activator, or rtPA) administration within 4.5 hours hours following the onset of an ischemic stroke improves the odds of...

24 hours may be sufficient to monitor blood cultures in febrile infants

1. The mean time to blood culture positivity in febrile infants with bacteremia was roughly 15 hours.  2. By 24 hours, 91% of blood cultures...

Analysis identifies radiology workflow bottlenecks in massive casualty incident

1. Analysis of emergency radiology utilization after the Boston Marathon Bombing demonstrated increased redundant imaging orders and significant delays in time to radiograph completion. 2....

Hypothermia in perinatal asphyxia encephalopathy preserves IQ

1. Hypothermia for newborns with perinatal asphyxia encephalopathy provided a long-term benefit in preserving IQ among survivors for those up to ages 6 and...

Fingolimod (Gilemya) shows promise in treatment of intracerebral hemorrhage

1. Treatment with fingolimod reduced perihematomal edema (PHE) and reduced the numbers of circulating lymphocytes in patients with intracerebral hemorrhage (ICH). 2. 100% of patients...

Preterm infant mortality lower at high volume neonatal centers

1. Infants less than 27 weeks gestation born at high volume centers had lower neonatal mortality and lower any in-hospital mortality, regardless of center’s...

Pediatric brain injury unlikely with isolated loss of consciousness

1. In children with isolated loss of consciousness after blunt trauma, the risk of clinically important traumatic brain injury was low if there were...

2 Minute Medicine Rewind June 30 – July 7, 2014

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Effect of Erythropoietin and Transfusion Threshold on...

Shunt settings may have little effect on intracranial pressure in hydrocephalus

1. Shunt valve settings had less of an effect on patient intracranial pressure (ICP) than previously predicted by in vitro shunt testing.  2. Patient ICP...
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