Patients with moderate-severe traumatic brain injury may achieve favourable functional outcomes within 12 months...

1. More than half of patients who experienced moderate-severe traumatic brain injury (ms-TBI) achieved favourable functional outcomes after 12 months of recovery, as measured...

Canakinumab not associated with increased survival without invasive mechanical ventilation among patients hospitalized with...

1. Among patients hospitalized with severe COVID-19 and hyperinflammation, treatment using the anti-interleukin-1β antibody canakinumab, compared with placebo, did not significantly increase the likelihood...

Computed tomography findings may be useful in prognostication for mild traumatic brain injury

1. Computed tomography (CT) findings improved generalized estimating equation models predicting whether a patient would experience incomplete recovery or unfavorable outcome in mild traumatic...

Predicting mortality among septic patients presenting to the emergency department–a cross sectional analysis using...

1. In a large cohort from Sweden, six variables focused on symptoms, observations, and mode of arrival to the hospital, were found to be...

7-day antibiotic therapy is noninferior to 14-day therapy in afebrile men with urinary tract...

1. A double-blinded, randomized controlled trial found that there were no significant differences between afebrile men treated for 7 days versus 14 days of...

Short-term seizure prophylaxis maximizes quality-adjusted life-years in simulated spontaneous intracerebral hemorrhage patients

1. A risk-guided strategy of using short-term secondary prophylaxis in intracerebral hemorrhage patients, and long-term secondary therapy after late seizures, optimized quality-adjusted life-years in...

Delayed endovascular thrombectomy associated with greater clinical benefit among patients with mismatch imaging profiles...

1. The findings supported the use of endovascular thrombectomy in patients who met criteria for either the clinical or target perfusion imaging mismatch profiles,...

Targeted screening not superior to nontargeted screening for human immunodeficiency virus in the emergency...

1. Targeted versus nontargeted HIV screening in the emergency department resulted in a similar number of new HIV diagnoses, yet a lower percentage of...

Pathological computed tomography features associated with adverse outcomes after mild traumatic brain injury

1. For mild traumatic brain injury, various pathological findings were associated with different prognostic implications for mild traumatic brain injury up to 1 year.  Evidence...

Active management superior to expectant management for persisting pregnancy of unknown location

1. Active management (methotrexate or uterine evacuation followed by methotrexate if needed) more frequently resulted in pregnancy resolution among patients with persisting pregnancy of...

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