High cumulative-dose isotretinoin treatment decreases risk of acne relapse

Image: PD 1. Patients receiving 220 mg/kg or more of oral isotretinoin had a significantly decreased risk of acne relapse at 1 year after treatment...

Zofran bests Diclegis for pregnancy-associated nausea

1. Pregnant women randomized to receive ondansetron (Zofran) reported greater reduction in both nausea and vomiting than those who received doxylamine-pyridoxine (Diclegis). 2. The...

Hopkins Frailty Score is best predictor of postoperative complications

Image: PD  1. Intermediately frail or frail patients, as determined by the Hopkins Frailty Score, had more post-op complications.  2. Some frailty-related predictors of complications may...

Low adult vaccination rates due to financial barriers

Image: PD  1. From a survey of general internists (GIMs) and family practice physicians (FMs), the most common barriers of physician-provided adult vaccines were financial,...

Continuous infusion of beta-lactams may be superior to bolus therapy

Jan 9th - Continuous infusion of beta-lactam antibiotics yielded a higher plasma concentration and higher rates of clinical cure in patients with severe sepsis.  Image: PD 1. ...

Sentinel lymph node surgery associated with a high false negative rate in node-positive breast...

Image: PD  1. Among women with node positive cN1 breast cancer, the false negative rate of sentinel lymph node surgery was 12.8%, above a previously...

Transvaginal ultrasound is the best diagnostic method for ectopic pregnancy

Image: PD 1. With a sensitivity of 88% and specificity of 88% for detecting ectopic pregnancy, transvaginal sonography was the single best diagnostic method of those...

New AAP guidelines against albuterol for bronchiolitis

1. A new American Academy of Pediatrics (AAP) Clinical Practice Guideline has been released for the diagnosis and management of bronchiolitis. 2. These guidelines include...

New antiviral drug pritelivir may reduce symptoms of HSV-2

Image: PD  1. Patients with HSV-2 treated with the helicase-primase inhibitor, pritelivir, had reduced viral shedding over 28 days when compared to patients treated with...

Revised autism screening tool (M-CHAT-R/F) may allow for earlier diagnosis

Image: PD 1. The Modified Checklist for Autism in Toddlers Revised with Follow-Up (M-CHAT-R/F) is an effective and reliable test for detecting autism spectrum disorder...
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