[Ann Emerg Med.] Topical antibiotics help prevent infection in minor wounds

Image: CC Primer: Uncomplicated soft tissue injuries are one of the most common ailments treated in the emergency department. However, there has been little agreement...

[CANCER] Marijuana associated with increased risk of germ cell and nonseminoma testicular cancer

Image:CC Primer: The onset of testicular germ cell tumors (TGCTs) typically occurs during puberty, and various studies have implicated changes in steroid hormones as culprits...

[BMJ] Elevated rheumatoid factor associated with 26x risk of developing rheumatoid arthritis

Image: CC/James Heilman Primer:  Rheumatoid factors (RF)  are autoantibodies  directed against the Fc portion of immunoglobulin.  Serum IgM RF occurs in 75-80% of patients with...

[JAMA] Clopidogrel lacks effectiveness in diabetics as compared to non-diabetics after myocardial infarction

Image: CC/Trounce Primer: The 2011 AHA/ACCF guidelines for secondary prevention for patients with known coronary disease include a Class IB recommendation for 75mg clopidogrel as...

[The Lancet] Longer duration of resuscitation efforts associated with increased survival in patients with...

Image: CC/Rama Primer: When dealing with cardiac arrests, one of the biggest dilemmas facing clinicians is deciding when to stop resuscitation efforts. Little research evidence...

[JAMA] Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in...

Image: CC. MRI of the heart.  Primer: Pathology studies suggest that subclinical ruptures of coronary atherosclerotic plaques occur frequently, which may result in unrecognized myocardial...

[NEJM] Tight glycemic control versus standard care after pediatric cardiac surgery

Image: Public Domain. Pediatric surgery in Haiti. Primer: Tight glycemic control has been shown to reduce morbidity and mortality in certain critically ill adult patients,...

[BMJ] Young women with BRCA1/2 mutations exposed to diagnostic radiation have higher risk of...

Image: PD. Chest x-ray.  Primer: We know that BRCA1/2 are involved in the repair of double-strand breaks. About one in 400 women have the mutation...

[JAMA] Risk of malignancies in patients with rheumatoid arthritis treated with biologic therapy: a...

Image: CC/Martin Steinhoff. Arthritis of the interphalangeal joints. Primer: In certain rheumatoid arthritis (RA) patients, treatment with typical disease-modifying anti-rheumatic drugs (DMARDs), including methotrexate, may...

[NEJM] No difference in survival between intermittent androgen deprivation therapy and continuous therapy for...

Image: CC/EAS. Human PSA.  Primer: Androgen deprivation therapy is the cornerstone for metastatic prostate disease. Intermittent therapy, essentially cycles of androgen deprivation followed by exposure...

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