Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Postoperative radiotherapy in pIIIA-N2 Non–Small Cell Lung Cancer after resection and chemotherapy

1. Postoperative radiotherapy for pIIIA-N2 non-small cell lung cancer did not improve disease-free survival or overall survival, but did improve locoregional recurrence-free survival. Evidence Rating...

Nicotine replacement therapy for expectant fathers

1. A combined smoking cessation intervention almost doubled the odds of expectant fathers achieving remission, compared to cessation advice alone. 2. Expectant fathers in the...

Fetoscopic endoluminal tracheal occlusion improves infant survival for congenital diaphragmatic hernia

1. Fetoscopic endoluminal tracheal occlusion (FETO) was shown to improve survival to discharge in infants with severe left congenital diaphragmatic hernia. 2. The FETO surgical...

Pembrolizumab plus concurrent chemoradiation therapy associated with robust antitumor activity in patients with locally...

1. Concomitant pembrolizumab plus chemoradiation therapy was associated with improved antitumor activity and safety profile in patients with previously untreated, locally advanced, stage III...

Randomized trial of plant-derived vaccine for COVID-19

1. A plant-derived, virus-like particle displays the SARS-CoV-2 spike glycoprotein and appears to be a promising candidate for a vaccine. 2. Adverse outcomes were mild-to-moderate,...

Critically ill COVID-19 patients in Africa may have worse outcomes compared to global rates...

1. In-hospital mortality within 30 days of admission for COVID-19 was 48% (vs. global mortality 31.5%). 2. Increased age, underlying comorbidities and delay in admission...

Dexamethasone vs methylprednisolone high dose for COVID-19 pneumonia

1. Hospitalized COVID-19 patients receiving high-dose methylprednisolone followed by oral prednisone had improved clinical outcomes compared to patients receiving dexamethasone. Evidence Rating Level: 2 (Good) In...

Tezepelumab reduced annual exacerbation rates in patients with severe asthma

1. Subcutaneous tezepelumab treatment reduced the rate of annual asthma exacerbations in patients with severe asthma compared to the placebo group. 2. No significant differences...

BNT162b2 mRNA vaccine shows benefit against symptomatic and asymptomatic SARS-CoV-2 infection 

1. Vaccinated individuals reported fewer SARS-CoV-2 infections and a lesser proportion of cases were symptomatic compared to the unvaccinated cohort. 2. BNT162b2 mRNA vaccine showed...

Delayed antibiotic prescribing is a safe and effective for respiratory tract infections in a...

1. There was no difference in follow-up symptom severity between patients who received immediate or delayed antibiotics for respiratory tract infections. 2. Delaying antibiotics was...

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