Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Tocilizumab may improve survival in COVID-19 patients with hypoxia and systemic inflammation 

1. Compared to usual care, fewer patients in the tocilizumab group died within 28 days of randomization. 2. Patients allocated tocilizumab were more likely to...

Rifapentine-moxifloxacin noninferior to standard of care treatment for pulmonary tuberculosis

1. Rifapentine-moxifloxacin treatment was shown to be non-inferior compared to standard therapy for tuberculosis. 2. Rifapentine without moxifloxacin treatment was shown to be inferior to...

Vulnerability of Never-Smoking Youth to Cigarette Smoking and Tobacco Industry Marketing

1. In a large and diverse cohort study, multiple susceptibility factors accurately predicted smoking outcomes 4 years later.  2. Exposure to tobacco marketing and electronic...

Infectivity of SARS-CoV-2 in children compared with adults

1. Children are most likely not the dominant drivers of COVID-19 transmissions, as their COVID test specimens were not as likely to grow in...

Sotatercept decreased vascular resistance in pulmonary arterial hypertension

1. Treatment with sotatercept decreased pulmonary vascular resistance in patients with pulmonary arterial hypertension. 2. Sotatercept caused adverse side effects of thrombocytopenia and increased hemoglobin...

Dexmedetomidine and propofol had similar outcomes in septic, mechanically ventilated adults

1. Treatment with dexmedetomidine was shown not to differ from propofol treatment in adult patients with sepsis who were under mechanical ventilation. 2. No significant...

Epidemiological and virological characteristics of respiratory tract infections in children during COVID-19 outbreak

1. In a large cohort of children from China, there was a significant decrease in outpatient visits and respiratory tract infections during the COVID-19...

Comparative outcomes between COVID-19 and influenza patients placed on veno-venous extracorporeal membrane oxygenation

1. COVID-19 patients with severe ARDS on veno-venous extracorporeal membrane oxygenation were nearly three times as likely to experience in-hospital death compared with influenza...

Use of bamlanivimab for patients with mild to moderate COVID-19 infection

1. Patients from a large academic medical center with mild to moderate COVID-19 in receipt of the monoclonal antibody bamlanivimab had a lower 30-day...

Initial effects of COVID-19 on patients with end-stage kidney disease

1. Patients with end-stage kidney disease were at increased risk of COVID-19-related mortality, particularly among non-Hispanic Black patients. Evidence Rating Level: 3 (Average) End-stage kidney disease...

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