• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Dermatology

Increased risk of non-melanoma skin cancer with subsequent keratinocytes carcinoma

byShirin BajajandAdam Whittington
January 25, 2015
in Dermatology, Oncology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. The risk for another non-melanoma skin cancer (NMSC) was significantly higher after a non-first NMSC diagnosis compared to the risk for another NMSC after a first-time NMSC diagnosis.

Evidence Rating Level: 2 (Good)

Study Rundown: NMSC – basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) – place tremendous burden on the US healthcare system, as more than 3.5 million tumors are treated annually. It is well understood that patients with NMSC are at increased risk for the development of subsequent new NMSCs; however few studies have compared cumulative risk after first-time vs. after multiple previous NMSCs diagnosis, which prompted this investigation. Authors found a greater magnitude of risk for subsequent tumor development after the diagnosis of multiple NMSCs, than after a first-time diagnosis (at 1 year the risk was 43.9% vs. 14.5%, respectively). While the prospective study design and large cohort strengthened the study, the demographic was restricted to a single city thereby limiting the generalizability of the findings.

Click to read the study in JAMA Dermatology

Relevant Reading: How Likely Is Another Nonmelanoma Skin Cancer?

In-Depth [prospective cohort]: This study consisted of 1284 patients who had been diagnosed with 1633 primary BCCs or SCCs at enrollment. The mean age was 67, 71.5% of the cohort was male, tumors were most commonly on the head and neck (62.2%), and most patients presented with a single NMSC. Patients were followed for a mean of 5.7 years. After first time diagnosis of NMSC, the risk of subsequent NMSC was 31.1% (95% CI, 27.3%-35.3%) at 3 years and 40.7% (95% CI, 36.5%-45.2%) at 5 years as compared to the risk after a non-first NMSC: 71.1% (95% CI, 69.1%-73.0%) at 3 years and 82.0% (95% CI, 80.2%-83.7%) at 5 years. To demonstrate the magnitude of the difference in risk between cohorts: after first life-time NMSC, the risk of developing a subsequent tumor at 10 years was 59.6% which was comparable to the risk of developing subsequent tumor within 2 years after the diagnosis of non-first lifetime NMSC (61.5%).

More from this author: Tech-aided surveillance of patients at high risk for melanoma aids early diagnosis, Indoor tanning linked to high skin cancer risk in US and abroad, Free drug samples may alter prescription habits of dermatologists, Atopic dermatitis may be more persistent than previously understood

RELATED REPORTS

#VisualAbstract: Combination of spartalizumab plus dabrafenib and trametinib does not significantly improve survival in BRAFV600-mutated metastatic melanoma

#VisualAbstract: Pembrolizumab reduces disease recurrence in completely resected stage IIB/IIC melanoma

#VisualAbstract: Ruxolitinib use may be associated with higher incidences of nonmelanoma skin cancers

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. No article should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2 Minute Medicine, Inc.

Tags: basal cell carcinomaskin cancer
Previous Post

Danish case control study links oral contraceptives with glioma

Next Post

Melanoma immunohistochemical analysis useful to determine BRAFV600E mutation status

RelatedReports

#VisualAbstract: Combination of spartalizumab plus dabrafenib and trametinib does not significantly improve survival in BRAFV600-mutated metastatic melanoma
StudyGraphics

#VisualAbstract: Combination of spartalizumab plus dabrafenib and trametinib does not significantly improve survival in BRAFV600-mutated metastatic melanoma

July 27, 2022
#VisualAbstract: Pembrolizumab reduces disease recurrence in completely resected stage IIB/IIC melanoma
StudyGraphics

#VisualAbstract: Pembrolizumab reduces disease recurrence in completely resected stage IIB/IIC melanoma

July 12, 2022
#VisualAbstract: Ruxolitinib use may be associated with higher incidences of nonmelanoma skin cancers
StudyGraphics

#VisualAbstract: Ruxolitinib use may be associated with higher incidences of nonmelanoma skin cancers

April 26, 2022
#VisualAbstract: Solid organ transplant recipients are at an increased risk of developing non-melanoma skin cancers
StudyGraphics

#VisualAbstract: Solid organ transplant recipients are at an increased risk of developing non-melanoma skin cancers

April 12, 2022
Next Post
Melanoma immunohistochemical analysis useful to determine BRAFV600E mutation status

Melanoma immunohistochemical analysis useful to determine BRAFV600E mutation status

Wide-ranging health benefits from outdoor adult walking groups

Wide-ranging health benefits from outdoor adult walking groups

AAP strongly opposes marijuana use, supports decriminalization

AAP strongly opposes marijuana use, supports decriminalization

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Methamphetamine use associated with cardiovascular disease in hospitalized patients
  • Management of uncomplicated urinary tract infections amongst women in the United States Military Health System highly concordant with guidelines
  • Gout flares associated with a transient increase in subsequent risk of cardiovascular events
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.