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Quick Take: Neoadjuvant degarelix versus triptorelin in premenopausal patients who receive letrozole for locally...

...s with breast cancer receiving letrozole as neoadjuvant endocrine therapy (NET). In this randomized controlled trial, 51 premenopausal women with stage cT2 to 4b, estrogen receptor and progesterone receptor greater than 50%, and human epidermal growth factor receptor 2-negative invasive breast cancer were randomized to receive triptorelin 3.75 mg (administered intramuscularly on day 1 of every cycle) or degarelix 240 mg (administered subcutaneousl...

Longer-duration breast feeding not associated with lower risk of obesity in childhood

...diameter useful in determining frequency of surveillance , Maternal folic acid supplementation during early pregnancy associated with lower risk of autism , Energy drinks may be harmful to the health of adolescents , Early initiation of antiretroviral therapy linked with lower risk of cognitive impairment in HIV © 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without written consent from 2minutemedicine.com. Disclaimer...

Increased diabetes risk observed in gout patients

...ment on the effect of dietary factors, such as sugar drink intake, a clear link between gout and increased diabetes risk was thoroughly established. A follow up prospective cohort study would help validate the findings of this case-control study. Click to read the study, published the Annals of Rheumatic Disease Relevant Reading: Gout and the risk of type II diabetes among men with a higher cardiovascular risk profile In-Depth [case-control study]...

[Researcher Comment] Dietary salt intake associated with greater consumption of sugar-sweetened beverages in children

...ntrated on child and adolescent populations, as childhood obesity has been linked to both short- and long-term health consequences such as heart disease, stroke, diabetes, and certain cancers (1). While this epidemic has been particularly well-publicized in the US, where over a third of children and adolescents were overweight or obese in 2008, less dramatic but still alarming results have been recorded in other developed countries such as Austral...

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[CANCER] Marijuana associated with increased risk of germ cell and nonseminoma testicular cancer

...use thus skewing the results. However this is the third study to make this link and the authors propose several well thought-out plausible biological etiologies by which the cannabinoid system could tip the scales towards cancer. Thus, while more research is needed to examine the association, one must also consider that cannabinoid agonists or antagonists might be used as therapies for a number of diseases and could be exposing men to undue risk....

Genetic variant linked to poor patient survival following lung transplantation

...s role in post-transplant survival are needed. This current study explored links between genetic variations in the IgG antibody receptor gene (FCGR2A) and patient survival after lung transplant. The examined variants (CC-, CT-, and TT-genotype) included a single nucleotide polymorphism (SNP) previously linked to diseases with immunological pathways believed to contribute to transplant rejection. While no link was established between the genetic va...

Repeat bone mineral density testing may not improve prediction of fracture outcomes

...ogy and duration associated with cardiac resynchronization outcomes, New genetic link between type 2 diabetes and coronary heart disease © 2013 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors,...

Proton pump inhibitor use associated with development of chronic kidney disease

...most prescribed medications, often without a strong indication, have been linked to acute kidney injury (AKI). The theory is that recurrent bouts of AKI may lead to CKD. This study, which used data from two prospective cohorts, was conducted to evaluate the link between PPIs and incident CKD. The results of the study showed that use of proton pump inhibitors (PPIs) was associated with about 20 – 50% higher risk of developing chronic kidney diseas...

Meta-analysis supports Institute of Medicine’s vaccine safety findings

...measles/mumps/rubella (MMR) vaccine is not linked to autism but that it is linked to a risk of febrile seizures. 2. There is moderate evidence that links the rotavirus vaccination to a risk of intussusception and the hepatitis A vaccine to purpura. 3. There is strong evidence that vaccinations are not associated with childhood leukemias. Evidence Rating Level: 2 (Good) Study Rundown: Immunizations have significantly reduced the incidence of infect...

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