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2 Minute Medicine Rewind June 29, 2020

...fic regions, to provide a better understanding of the virulence of the SARS-CoV-2.   Prognostic value of functional capacity in different exercise protocols for heart disease 1. Prognosis of heart disease patients is associated not only with their exercise capacity, but also the type of exercise protocol used Evidence Rating: 2 (Good) Exercise testing is a common prognostic measurement used to assess heart disease patients. Exercise capacity, whic...

2 Minute Medicine Rewind October 19, 2020

...her amounts of weekly physical exercise were associated with better carotid-to-femoral pulse wave velocities but not with carotid distensibility, which are both markers of arterial stiffness. 2. Diabetic patients may benefit from a more profound correlation between physical exercise with carotid-to-femoral pulse wave velocity. Evidence Rating Level: 2 (Good) Arterial stiffness is a risk factor for cardiovascular disease, which can be altered by ph...

2 Minute Medicine Rewind May 3, 2021

...24% of the 11-17 group and 7% of adults. Additionally, the cycle threshold for RT-PCR was lowest in adults (18.7, IQR 17.9-30.4) compared to 22.2 in the 11-17 age group (IQR 18.3-29.0, p = 0.02) and 25.1 in the under 10 age group (IQR 17.7-31.3, p < 0.001). Lower cycle thresholds indicate higher quantities of viral genetic material in the samples. As well, the median TCID50/mL was lower in the 11-17 group (316, IQR 178-2125) compared to adults (56...

2 Minute Medicine Rewind October 5, 2020

...is well-established that the major risk factor for uterine rupture in high-income countries is scarring from previous uterine surgery, which became apparent after trial of labor after cesarean (TOLAC) increased in the early 1990s. The American College of Obstetricians and Gynecologists (ACOG) recommends that most women with one previous lower uterine segment cesarean can and should be offered TOLAC. That being said, there is a paucity of reliable...

2 Minute Medicine Rewind August 17, 2020

...r physical activity, such as the closure of athletic facilities and shelter-in-place orders. Since past research has associated lack of physical activity to poorer mental health, there is a growing need for empirical research regarding the restrictions’ effect on physical and mental health outcomes. The aim of this study was to investigate the association between perceived alterations in physical activity (due to the restrictions) and mental healt...

2 Minute Medicine Rewind Jan 25, 2021

...alized retinal vessel calibers, and sitting blood pressure, BMI, and weight-to-height ratio (WHtR) were measured. Compared to overweight and normal weight children, obese children had the smallest arteriolar fractal dimensions (1.211 vs 1.234 and 1.240, p-trend=0.004). Hypertensive systolic blood pressure was significantly associated with the narrowest central retinal arteriolar equivalents (CRAE) over elevated or normotensive systolic blood press...

2 Minute Medicine Rewind July 26, 2021

...s pathological features on CT were associated with different prognostic outcomes for mild TBI, with recovery being impacted anywhere from 2 weeks to 12 months after injury.   Suicide incidence and risk among patients with head and neck cancer in rural vs urban areas 1. Survivors of head and neck cancer (HNC) from rural American counties had double the rate of suicides compared to HNC survivors from metropolitan and urban counties. Evidence Rating...

2 Minute Medicine Rewind March 29, 2021

...n heart failure compared to normal and underweight patients. N-terminal pro-B-type NP (NT-proBNP), one of the gold standard biomarkers for risk stratification, diagnosis, and prognostication in heart failure, is also lower in obese individuals. This post-hoc analysis examined patients with heart failure with reduced ejection fraction (HFrEF) from the GUIDE-IT trial (Guiding Evidence-Based Therapy Using Biomarker-Intensified Treatment in HF). Multi...

2 Minute Medicine Rewind September 21, 2020

...nonpharmaceutical public health interventions to prevent resurgence of SARS-CoV-2 transmission in Canada 1. A computerized model predicted that 64.6% of Canadians will be infected with SARS-CoV-2 without any interventions. 2. With enhanced case detection and contact tracing, infection rate was predicted to be 0.4%, and 0.2% if sustained physical distancing was additionally achieved. 3. Keeping infection rate under 0.2% was the only scenario that k...

2 Minute Medicine Rewind November 16, 2020

...pital files. Evidence Rating Level: 1 (Excellent) Discussions regarding end-of-life plans among patients, family, and healthcare professionals are associated with numerous positive outcomes, such as better emotional functioning, increased symptom resolution, and less demanding interventions. Advanced care planning (ACP) encompasses these discussions, and allows patients to outline their goals of care, keep a record of these goals, and identify dec...

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