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Patient Basics: Friedreich’s Ataxia

...a segment of the genetic code on chromosome number 9 can have as many as 1,000 repetitions, instead of the normal range of 7 to 22. These repetitions produce an error that leads to a decreased production of frataxin. As free radicals accumulate within cells, and more and more cells are destroyed or altered, the long-term effects of Friedreich’s ataxia lead to a thinner spinal cord, enlarged heart muscle, disturbances in speech and eye movement, an...

Patient Basics: Non-Small Cell Lung Cancer

...Office 6116 Executive Blvd. Room 3036A Bethesda, MD 20892-8322 Toll-Free: 800-422-6237 TTY: 800-332-8615 http://www.nci.nih.gov/ American Cancer Society (ACS) 1599 Clifton Road, NE Atlanta, GA 30329-4251 Toll-Free: 800-227-2345 TTY: 866-228-4327 http://www.cancer.org/ American Lung Association 61 Broadway, 6th Floor New York, NY 10006 Phone: 212-315-8700 Toll-Free: 800-548-8252 http://www.lungusa.org/ National Heart, Lung, and Blood Institute (NHL...

Patient Basics: Abortion (Termination of Pregnancy)

...stone is taken orally as a pill. Approved for use in the United States in 2000, this drug counters the effect of progesterone, a hormone necessary for pregnancy. More than 3 million women in Europe and China have received this drug to end a pregnancy. Side effects include nausea, vomiting, vaginal bleeding and pelvic pain. These symptoms usually can be treated with medications. In rare instances, there may be heavy bleeding. In that case, you may...

Patient Basics: Drooping Eyelid (Ptosis)

...logical Disorders and Stroke P.O. Box 5801 Bethesda, MD 20824 Toll-Free: (800) 352-9424 http://www.ninds.nih.gov/ American Academy of Ophthalmology P.O. Box 7424 San Francisco, CA 94120 Phone: (415) 561-8500 Fax: (415) 561-8533 http://www.aao.org/ American Academy of Pediatrics (AAP) 141 Northwest Point Blvd. Elk Grove Village, IL 60007-1098 Phone: (847) 434-4000 Fax: (847) 434-8000 http://www.aap.org/ Myasthenia Gravis Foundation of America 5841...

Patient Basics: Schizophrenia

...al situations. Schizophrenia is surprisingly common, affecting 1 in every 100 people worldwide. Experts believe schizophrenia results from a combination of genetic and environmental causes. The chance of having schizophrenia is 10% if an immediate family member (a parent or sibling) has the illness. The risk is as high as 65% for those who have an identical twin with schizophrenia. Scientists have identified several genes that increase the risk of...

Patient Basics: Kidney Cancer

...cer Society (ACS) 1599 Clifton Road, NE Atlanta, GA 30329-4251 Toll-Free: 800-227-2345 http://www.cancer.org/ National Kidney Foundation 30 East 33rd St. New York, NY 10016 Phone: 212-889-2210 Toll-Free: 800-622-9010 Fax: 212-689-9261 http://www.kidney.org/ National Cancer Institute (NCI) U.S. National Institutes of Health Public Inquiries Office Building 31, Room 10A03 31 Center Drive, MSC 8322 Bethesda, MD 20892-2580 Phone: 301-435-3848 Toll-Fre...

Rates of multiple births and multiple embryo IVF procedures have decreased in the past...

...elines. The rate of twin births increased by a factor of 1.9 from 1971 to 2009 and seems to have leveled off; the rate of triplet and higher-order births increased by a factor of 6.7 from 1971 to 1998, with a decline of 29% from 1998 to 2011, following the initial release of IVF practice guidelines (P<0.001 for trend). Of note, the estimated proportion of twin births that were attributable to non-IVF fertility treatment increased from 16% in 1998...

Patient Basics: Scabies

...eone is dirty, careless or sexually promiscuous. Worldwide, approximately 300 million new cases of scabies occur each year in men, women and children of all ages and races. Groups that are especially vulnerable to catching scabies include: People who have multiple sex partners Anyone who lives in crowded conditions Patients and health care workers in hospitals and nursing homes Students, teachers and other caregivers in day-care centers People who...

Patient Basics: Food Poisoning

...roenterology (ACG) P.O. Box 342260 Bethesda, MD 20827-2260 Phone: 301-263-9000 http://www.acg.gi.org/ American Gastroenterological Association 4930 Del Ray Ave. Bethesda, MD 20814 Phone: 301-654-2055 Fax: 301-654-5920 http://www.gastro.org/ Center for Food Safety & Applied Nutrition U.S. Food and Drug Administration (FDA) 5100 Paint Branch Parkway College Park, MD 20740-3835 Toll-Free: 1-800-463-6332 http://vm.cfsan.fda.gov/ Food Safety and Inspec...

A word on stats [Perspective]

...to everything – including humans. Building on the work Graunt had started 200 years prior, Laplace showed how a range of human behaviors – whether someone lies in court; death rates and marriage rates; the number of female and male babies born each year; the number of letters sent to the Paris dead-letter office – all vary around a calculable mean. Adophe Quetelet, one of Laplace’s most zealous successors, showed that Scotsmen’s chests and even mu...

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