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2 Minute Medicine Rewind September 2, 2019

...both mother and infant. In addition to maternal and fetal assessment, timely delivery after 37 weeks’ gestation is recommended to minimize maternal and perinatal morbidity. In women with late preterm preeclampsia, between 34 and 37 weeks’ gestation, however, there is a lack of consensus surrounding the optimal time for delivery, with some centers opting for expectant management until 37 weeks’ gestation, or earlier delivery if indicated in the se...

Spontaneous early term delivery associated with subsequent preterm birth

...In women who experienced spontaneous onset of labor, those who spontaneously delivered early term (37-39wga) pregnancies were more likely to experience subsequent sPTB (OR 3.0, CI 1.44-6.16, p=0.003), while those who delivered spontaneously after 38.9wga were no less likely (p=0.8). By Denise Pong, MPH and Leah Hawkins, MD, MPH More from this author: Donor oocyte IVF making strides, Shortage of evidence assessing teratogenic drugs, HPV infection...

Childbearing decreased after C-sections

...men experiencing pregnancy and childbirth complications during their first delivery were less likely to have a subsequent live birth. Evidence Rating Level: 2 (Good) Study Rundown: This study used delivery data from over 50,000 primiparous women to determine whether Cesarean delivery, a common procedure in the U.S., is associated with decreased subsequent childbearing. Existing literature has produced mixed results. The present work uses a large s...

#VisualAbstract: A Randomized Trial of Prenatal n−3 Fatty Acid Supplementation and Preterm Delivery

...ar to control. Evidence Rating Level: 1 (Excellent) Study Rundown: Preterm delivery, delivery before 37 weeks of gestation, is associated with increased childhood morbidity and mortality. N-3 long-chain polyunsaturated fatty acids are known to play a role in modulating proinflammatory prostaglandins such as PGE2 and PGF2a that are associated with cervical ripening and uterine contractility. In this multicenter, double-blind randomized control tria...

Patient Basics: Head Injury In Children

...and severity of the injury. For example, pain from mild head injuries usually lasts for only a few minutes. Symptoms from a concussion often go away within minutes or hours after the injury, but a child may have some confusion, memory loss, difficulty concentrating, headaches, dizziness or fatigue that lasts for several days or even longer. This collection of symptoms, called post-concussion syndrome, sometimes can last for weeks or even months. T...

C-section in the second stage linked to future preterm birth

...t stage cesarean (OR = 5.8, p = 0.04). Compared to those delivering vaginally, women whose first delivery ended in a first stage cesarean were less likely to experience preterm birth (OR = 0.30, p = 0.049). More from this author: Contained morcellation for benign gynecologic surgeries feasible, minimize surgical risk, Oocyte vitrification not associated with adverse obstetric or perinatal outcomes, IUD contraception equally safe in teenagers as in...

Patient Basics: Preeclampsia And Eclampsia

...t? Preeclampsia is a condition that occurs only during pregnancy, and usually only after the 20th week. A woman with preeclampsia develops high blood pressure and protein in her urine, and she often has swelling (edema) of the legs, hands, face, or entire body. When preeclampsia becomes severe, it can cause dangerous complications for the mother and the fetus. One of these complications is eclampsia, the name for seizures that are associated with...
Classics Series, Landmark Trials in Medicine

Magnesium reduces cerebral palsy in infants delivered early preterm [Classics Series]

...ment or each of these factors. The diagnosis of cerebral palsy was rigorously determined by an annually certified pediatrician or pediatric neurologist if children met 2 or more strictly defined criteria, including motor delay, abnormal muscle tone or reflexes, persistence of primitive reflexes and movement abnormality. Among women with imminent delivery between 24 and 31 weeks gestation, those randomized to receive magnesium sulfate experienced a...

Parental stress linked to higher rates of child obesity and fast food consumption

...ence often shapes childhood behaviors and attitudes, additional stress likely negatively impacts parents’ ability to encourage healthy behaviors. The current study aimed to further explore the connection between parental stress and child obesity. Background reading: 1. Parenting stress impacts obesity-specific health-related quality of life in a pediatric obesity treatment-seeking sample [Journal of Developmental & Behavioral Pediatrics] 2. Psycho...

Development and validation of PEN-FAST clinical prediction tool for possible penicillin allergy

...ing and may aid clinicians in predicting patients with low risk of clinically significant penicillin allergy. The study found that a PEN-FAST score, utilizing the clinical severity, need for treatment, skin manifestations, and timing of the reported reaction, was able to predict patients who were low risk of having positive antibiotic allergy test results. These results were consistent in an external validation cohort data set. The PEN-FAST score...

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