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2 Minute Medicine Rewind June 29, 2020

...a leading cause of disability worldwide. There has been mixed evidence on the link between physical activity and chronic pain, in part due to the varied methods in which chronic pain is measured and reported. As well, there is a gap in the literature on this link in young adults, as most chronic pain studies focus on older adults. The current study uses a survey of Norwegian university students to examine the association between the level of phys...

2 Minute Medicine Rewind October 12, 2020

...te coronary syndrome data and percutaneous coronary intervention data from the UK. The population consisted of adults diagnosed with AMI from February to May 2019 (for the pre-COVID group) and from February to May 2020 (for the COVID group). Overall, the study found that 5.6% of all AMI hospital admissions were related to OHCA during the pandemic, whereas 3.6% of were OHCA-related in the pre-COVID group. There were significantly more AMI hospital...

2 Minute Medicine Rewind February 22, 2021

...15.8% in the first trimester, 27.9% in the second, and 56.3% in the third. The overall infection rate in pregnancy among trial sites was 13.9/1,000 deliveries. When comparing this to the overall infection rate among those aged 20-39 years in Washington State (7.3/1,000), the infection rate in pregnancy was a significant 1.7 times higher. Furthermore, when compared with those who delivered live births in Washington State in 2018, the proportion of...

2 Minute Medicine Rewind February 8, 2021

...ion rate include female sex, greater knee pain, higher BMI, and older age. Overall, the study showed that HTO is a procedure that can delay the need for a TKR in knee osteoarthritis patients, with 79% of patients not requiring a TKR 10 years after an HTO.   Use of high dose cyproterone acetate and risk of intracranial meningioma in women: cohort study 1. Long-term usage of cyproterone acetate (CPA) at high doses was associated with greater risk of...

2 Minute Medicine Rewind July 13, 2020

...hange in RALE score from baseline to day three to a decrease in RALE score over the same period, a higher risk of death at 90 days was observed (HR 3.39, 95% CI 1.14 to 10.09, p = 0.03). This study found that an early decrease in RALE score was associated with a decreased risk of mortality at 90 days among patients with ARDS. Such findings illustrate how serial chest X-ray imaging among such patients may be useful as a non-invasive prognostic mark...

2 Minute Medicine Rewind May 18, 2020

...n either group. In further health economic analysis, it was estimated that the net societal cost per patient was $3584 lower in ICBT versus face-to-face CBT. Study findings are highly supportive of the implementation of ICBT into regular practice as an effective alternative to face-to-face CBT for health anxiety. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study 1. Findin...

2 Minute Medicine Rewind December 7, 2020

...utes after administering the analgesic, to reflect the drugs’ peak action. Overall, the results showed no difference in pain score: For HBB, the mean score was 29±26 mm, while for acetaminophen, it was 30±29 mm. The adjusted difference between the groups was 1 mm (95% CI -7 to 7 mm). Furthermore, no significant differences were found for requirement of emergency analgesia, nor for adverse events and complications. In conclusion, HBB is not superio...

Special Rewind: COVID-19 Vaccine Edition. December 21, 2020

...either ChAdOx1 nCoV-19 (n = 153) or MenACWY (n = 534). Safety was assessed over the course of 28 days post-vaccination. Systemic and local reactions were found to be more common in the ChAdOx1 nCoV-19 group compared to the MenACWY group, but were similar to the Pfizer/BioNTech in being primarily composed of transient reactogenicity reactions such as chills, muscle ache, headache, malaise, fever, and pain (p<0.05), that were reduced with prophylact...

2 Minute Medicine Rewind September 21, 2020

...devices. The current study was a 1-year randomized controlled trial in the Netherlands, comparing AF diagnoses with opportunistic screening versus usual care. The study population included 17,976 patients aged 65 and over, from 96 primary care practices in the country; each practice was randomized into one of the two groups, stratified by the existing number of AF patients in the practice. The opportunistic group screened any primary care patient...

2 Minute Medicine Rewind January 11, 2021

...benefits for lansoprazole over placebo in the secondary outcome measures. Overall, the study did not show evidence for the advantage of treating persistent throat symptoms with PPIs, which has implication for informing clinical guidelines as well as current prescription practices by primary care doctors and otolaryngologists. Image: PD ©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent...

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