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2 Minute Medicine Rewind December 7, 2020

...east 40 mm on a 100 mm visual analogue scale (mean pain score was 60±18 mm for HBB, and 62±17 mm for acetaminophen). The primary outcome was pain score 80 minutes after administering the analgesic, to reflect the drugs’ peak action. Overall, the results showed no difference in pain score: For HBB, the mean score was 29±26 mm, while for acetaminophen, it was 30±29 mm. The adjusted difference between the groups was 1 mm (95% CI -7 to 7 mm). Furtherm...

2 Minute Medicine Rewind October 12, 2020

...study was a randomized controlled pilot trial comparing clinical outcomes for women at high risk for PTBs, provided with the midwifery continuity of care model, versus the standard maternity care model. This study took place at an inner-city maternity service in London, UK, and consisted of 331 women with 168 randomly assigned to the midwifery continuous care group (also known as the POPPIE group). The primary outcome measured was the initiation...

2 Minute Medicine Rewind July 27, 2020

...C was the same among all 3 groups: The adjusted mean change±SE was 3.2±5.7 for SSBs, -2.4±5.4 for ASBs, and -3.2±5.1 for USBs (p = 0.65). Body weight (p = 0.66) and fat mass (p = 0.27) were also the same. However, participants in the highest tertile of trunk fat had a significant body weight increase (p = 0.002) in the SSB group (4.4±1.0 kg) compared to ASB (0.5±0.9 kg) and USB (-0.2±0.9 kg). Finally, sweetness threshold (the concentration rated a...

2 Minute Medicine Rewind June 29, 2020

...tality was 0.82 (95% CI, 0.81-0.82) for users and 0.81 (95% CI, 0.79-0.83) for non-users (P interaction = 0.54). For cancer, the HR was 0.82 (95% CI, 0.81-0.83) in users and 0.82 (95% CI, 0.78-0.85) in non-users (P interaction = 0.94). And for CVD, the HR was 0.81 (95% CI, 0.79-0.82) in users and 0.74 (95% CI, 0.69-0.78) in non-users (P interaction = 0.01). Compared to cancer and all-cause mortalities, healthy lifestyle factors in CVD have the lar...

2 Minute Medicine Rewind August 24, 2020

...tive cohort study aimed to determine which factors are the best predictors for SR maintenance, even before DCCV is applied. The population consisted of 146 patients with persistent AF, lasting at least seven days, to be treated with DCCV. Numerous factors related to the electrical and mechanical aspects of the atria were measured through echocardiographic imaging, prior to DCCV. After 12 months, 41.8% of patients had SR maintained. The results fou...

USPSTF Update: Screening adults for unhealthy drug use has moderate net benefit

...All were found to significantly reduce the rate of relapse (pooled RR 0.73 for naltrexone, 0.75 for buprenorphine and/or methadone) and increase patient retention (pooled RR 1.71 for naltrexone, 2.58 for buprenorphine and/or methadone). Psychosocial treatment tools significantly increased the likelihood of likelihood of abstaining from drug use at 3-4 months (pooled RR 1.6), with the greatest benefit seen in cannabis users (RR 2.08) and those who...

2 Minute Medicine Rewind October 19, 2020

...to the role of vitamin D during childbirth and appropriate supplementation for pregnant mothers. Nonetheless, further studies should be done with a greater number of patients and across multiple study centres.   The Incidence, Risk Factors and In-Hospital Mortality of Acute Kidney Injury in Patients After Surgery for Acute Type A Aortic Dissection: A Single-Center Retrospective Analysis of 335 Patients 1. For patients undergoing surgical intervent...

2 Minute Medicine Rewind August 17, 2020

...ncluding 909 same-sex twin pairs. Twins were used in this study to control for genetic and shared environmental factors, as changes in perceived physical activity were anticipated to be stemming from non-shared environmental factors. Participants completed an online survey which assessed perceived changes in physical activity (increased, decreased, or stayed the same), stress (using the 5-point Likert-type Perceived Stress Scale), and anxiety (usi...

2 Minute Medicine Rewind October 5, 2020

...taminase type 2 (anti-TG2) antibodies were tested at three years to assess for the development of celiac disease. For this analysis, a total of 1,004 infants were tested for anti-TG2 antibodies, 488 in the EIG and 516 in the SIG. At three years, nine children, seven in the SIG and 2 in the EIG, had sufficiently elevated anti-TG2 antibodies and were referred for further investigation. Ultimately, all seven infants in the SIG received a diagnosis of...

2 Minute Medicine Rewind November 16, 2020

...s in males, and for healthy life expectancy, it ranged from 9.5-13.5 years for females and 2.6-6.7 years for males. In conclusion, this study demonstrates that although life expectancy is increasing for IBD patients, these individuals continue to have significantly lower life and healthy life expectancies than the general population. Image: PD ©2020 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written c...

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