Tag: Coronavirus

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 1. SARS-CoV-2 appears to have the longest surface viability on plastic and stainless steel compared to in aerosol, copper, or cardboard with detection of viable virus up to 72 hours post application on plastic. 2. Stability of SARS-CoV-2 appears to similar...
1. Study findings suggest that risk factors predisposing patients to progression to acute respiratory distress syndrome (ARDS) include older age, neutrophilia, and organ and coagulation dysfunction. 2. Some factors, including high fever, were associated with higher rates of ARDS development but lower rates of mortality. 3. In this observational study with...
1. Clinical data from early cases in China describe rapid transmission and variable degrees of illness. 2. Patients commonly presented with fever and cough following a median incubation period of 4 days, though many patients presented without fever and had normal radiologic findings. Evidence Rating: 3 (Average) Clinical data from early cases...
1. SARS-CoV-2 appears to have the longest surface viability on plastic and stainless steel compared to aerosol, copper, or cardboard with detection of viable virus up to 72 hours post application on plastic and 3 hours in aerosol. 2. Surface and aerosol stability of SARS-CoV-2 appears to be similar to...
Clinical Course and Risk Factors for Mortality of Adult Inpatients With COVID-19 In Wuhan, China: A Retrospective Cohort Study 1. In-hospital COVID-19-related death was associated with older age, d-dimer levels greater than 1.0μg/mL, and higher Sequential Organ Failure Assessment upon assessment. 2. Median viral shedding in survivors was 20 days but...
1. Analysis of the initial transmission dynamics of the novel corononvirus revealed the epidemic to be doubling in size approximately every week with each infected individual having transmitted the disease to 2.2 other persons on average. 2. Mean incubation period was estimated to be 5.2 days, with the 95th percentile...
Image: PD  In this section, we will highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease Vedolizumab is a humanized monoclonal antibody targeting α4β7 integrin, which modulates gut lymphocyte...
Image: PD June 24 – June 30, 2013 In this section, we will highlight the some of the high-impact studies, updates, and analyses published in medicine during the past week. Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack In this multicenter open label RCT, patients with a minor ischemic stroke...
Image: PD Middle East Respiratory Syndrome Coronavirus (MERS-CoV) 1. Transmission of Middle East Respiratory Syndrome associated with healthcare facilities occurs via person-to-person contact.  2. Analysis of a single outbreak in Saudi Arabia identifies an incubation period of 5.2 days and a serial interval of 7.6 days.  Evidence Rating Level: 2 (Good) Study Rundown: The novel...
Image: PD 1. Two cases of Middle East Respiratory Syndrome coronavirus (MERS-CoV) in France were identified in this report. 2. Incubation time of the virus was observed to be up to 12 days, prolonged versus the one to nine day incubation in previously observed cases. This may have implications for quarantine...