Tag: diabetes

Image: PD 1.     Weight loss and glycemic control are improved in the short term to a greater extent in nonmorbidly obese diabetic patients who have undergone bariatric surgery relative to nonsurgical intervention. 2.     Gastric bypass was more effective than gastric banding for weight loss and glycemic control. 3.     Since the literature does...
Image: PD 1. In mild to moderately obese patients, gastric bypass surgery plus intensive lifestyle modifications demonstrates better cardio-metabolic risk factor reduction than lifestyle modification alone in one year. 2. Patients in the gastric bypass group took fewer medications in comparison to patients in the lifestyle-medical management group. Evidence Rating Level: 1 (Excellent) Study...
Image: PD 1. Moderate evidence exists to suggest that treatment of gestational diabetes (GDM) is associated with a lower likelihood of preeclampsia, shoulder dystocia, and macrosomia. Little evidence exists to suggest an association of GDM treatment with short-term harm. 2. Evidence was insufficient for the association of treatment with numerous outcomes, including long-term...
Image: PD 1. Women with lower melatonin secretion had a significantly higher incidence of type 2 diabetes. 2. Women with a higher melatonin secretion had lower BMI, as well as decreased inflammatory markers and prevalence of hypertension. Study Rundown: This case-control study demonstrates an interesting association between melatonin secretion and type 2...
Image: PD 1. Overnight hypoglycemia was less likely with an artificial pancreas compared to a sensor-augmented insulin pump in children with type 1 diabetes.  2. There was significantly less variation in overnight glycemic levels using the artificial pancreas. This multi-national crossover study measured the efficacy of an artificial pancreas compared to a...
Feb 24th – A sustained relationship with a primary care provider improves outcomes and reduces costs for a large cohort of Korean type II diabetes patients. Image: CC/LProfil. Diabetes Prevalence (Orange=highest) 1. Using the same physician for all ambulatory care was linked to improved outcomes in newly diagnosed type II diabetes...
Feb 23rd- Asthmatic women were more likely to experience spontaneous abortion than healthy women. Image: CC/JHeilman 1. Asthmatic women were more likely to experience spontaneous abortion than healthy women. 2. Maternal age, teratogenic medications, hypertension and diabetes mellitus were also associated with increased odds of spontaneous abortion. This retrospective cohort study evaluated...
Classics Series, Landmark Trials in Medicine
1. Intensive glycemic control was associated with significantly lower rates of new or worsened nephropathy when compared to conventional glycemic control. 2. There was no significant reduction in major macrovascular events associated with intensive blood sugar control. Original Date of Publication: June 12, 2008 Study Rundown: Glycated haemoglobin (HbA1c) levels are frequently used...
Classics Series, Landmark Trials in Medicine
1. Previous studies suggest that intensive blood glucose control reduces the risk of microvascular complications, though questions remained regarding the impact on macrovascular complications and mortality. 2. This study found that targeting HbA1c <6.0% resulted in higher risk of cardiovascular and all-cause mortality as compared with standard therapy (i.e., targeting...
Image: CC/Ash Key Study Points: 1.       Increased plasma bicarbonate is associated with a decreased odds of developing diabetes. 2.       Each unit increase in plasma bicarbonate was associated with a 4% decrease in the odds of developing diabetes. Primer: It is currently thought that metabolic acidosis may play a role in the development of...