Tag: type 2 diabetes

1. Compared to patients of European descent, poorer health outcomes were seen among Māori and Pacific New Zealanders with type 2 diabetes. 2. Māori patients had the highest incidence rate of all-cause mortality, cardiovascular mortality, and cancer mortality. Evidence Rating Level: 2 (Good) Study Rundown: Disparities associated with ethnicity and socioeconomic status...

1. 10-year remission rates were significantly higher for Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion (BPD) than medical therapy. 2. Patients in the BPD and RYGB groups had fewer diabetes-related complications.  Evidence Rating Level: 1 (Excellent) Study Rundown: Compared to conventional therapy, metabolic surgery results in significant short-term improvements among patients with...

1. Sotagliflozin was shown to lower the risk of total number of deaths from cardiovascular causes and hospitalizations and urgent visits for heart failure in patients with diabetes and recent worsening heart failure compared to placebo. 2. Sotagliflozin was shown to be similar in the percentage of patients with adverse...

The association of depression with subsequent dementia diagnosis: A Swedish nationwide cohort study from 1964 to 2016 1. There is a significantly increased risk of dementia in patients with previously diagnosed depression, with the highest risk observed in patients diagnosed with severe depression Evidence Level: 2 (Good) The prevalence of dementia is on...

1. In this randomized controlled trial, a behavioral intervention increased physical activity and reduced sedentary activity in type 2 diabetes patients. 2. The effects of behavioral intervention were sustained over 3 years. Evidence Rating Level: 1 (Excellent)       Study Rundown: Regular physical activity is recommended for patients with type 2 diabetes (DM2), though adherence...

1. In this randomized controlled trial, a behavioral intervention increased physical activity and reduced sedentary activity in type 2 diabetes patients. 2. The effects of behavioral intervention were sustained over 3 years. Evidence Rating Level: 1 (Excellent)       Study Rundown: Regular physical activity is recommended for patients with type 2 diabetes (DM2), though...

1. Individualized glycemic control for type 2 diabetic patients could save the United States billions of dollars annually compared to uniform glycemic control. 2. Although individualized control increased complications (resulting in slightly decreased life expectancy), it created more quality-adjusted life-years (QALYs) due to reduced medications and hypoglycemic events. Evidence Rating Level:...

1. In this prospective cohort study, history of gestational diabetes (GDM) was associated with increased risk of cardiovascular disease (CVD) later in life. 2. After adjustment, women with GDM who did not go on to developing Type 2 Diabetes (T2DM) did not have an increased CVD risk, whereas women with...

1. This randomized clinical trial showed that, among patients with type 2 diabetes, oral semaglutide resulted in better glycemic control compared to placebo over 26 weeks. 2. A decrease in mean HBA1C in the subcutaneous semaglutide group was also significantly greater than the placebo group. Evidence Rating Level: 1 (Excellent) Study Rundown:...

1. Type 2 diabetic patients at high-risk for cardiovascular events treated with the ultra long-acting insulin degludec experienced cardiovascular events at an incidence noninferior to patients treated with glargine. 2. Patients treated with degludec experienced lower rates of severe hypoglycemic events compared to those treated with glargine. Evidence Rating: 1 (Excellent) Study...