Second-line single-agent chemotherapies or immune checkpoint inhibitors have provided suboptimal response rates and survival benefits in patients with locally advanced...

Hospital volume and outcomes for acute pulmonary embolism: multinational population-based cohort study Patients with pulmonary embolism (PE) can present with...

Multiple myeloma often develops from the precursor condition monoclonal gammopathy of undetermined significance (MGUS), which is detectable in peripheral blood....

Association between heart failure and postoperative mortality among patients undergoing ambulatory noncardiac surgery Patients with heart failure are at an...

The prevalence of hypertension is rapidly increasing in low-income and middle-income countries (LMICs). To effectively target interventions and monitor progress...

Plasmodium vivax (P. vivax) malaria is a major cause of morbidity and mortality throughout the world. Primaquine, an 8-aminoquinoline, is...

Roxadustat for anemia in patients with kidney disease not receiving dialysis Chronic kidney disease (CKD)-related anemia is associated with significant...

The two main surgical options for late-stage medial compartment osteoarthritis of the knee are partial knee replacement (PKR) and total...

The risk of adverse cardiovascular outcomes in patients hospitalized with acute coronary syndrome (ACS) is highest in elderly patients. Although...

Patients with heart failure are at an increased risk of experiencing postoperative adverse events and mortality. While ambulatory surgical procedures...