Melanoma as a possible cause of autoimmune encephalitis

1. A woman developed anti-AMPA receptor encephalitis in the setting of metastatic melanoma.2. Following a short delay, she responded well to vemurafenib and cobimetinib....

Quick Take: Association of Atopic Dermatitis With Sleep Quality in Children

Atopic dermatitis, a common disorder in the pediatric population, is associated with pruritus that is often worse at night and, thus, can interfere with...

Quick Take: Association of Disease Recurrence With Survival Outcomes in Patients With Cutaneous Squamous...

Cutaneous squamous cell carcinoma of the head and neck (cSCC-HN) generally has a favorable prognosis, however, there is a subset of patients who experience...

Quick Take: Association of Systemic Antibiotic Treatment of Acne With Skin Microbiota Characteristics

Systemic antibiotics are commonly used in the treatment of acne. However, the impact of their use on the complete bacterial microbiome of skin has...

New molecular probes for melanoma imaging and treatment [PreClinical]

1. α-melanocyote stimulating hormone (α -MSH) and its analogs can bind tightly to the melanocortin-1 receptor (MC1R), a G protein-coupled receptor that is overexpressed...

Eczema more prevalent among older adults than previously thought

1. The results of this study suggested that the prevalence of atopic dermatitis increased with age among a U.K. adult primary care population.2. The...

Quick Take: Long-Term Survival of Patients With Melanoma With Active Brain Metastases Treated With...

Immune checkpoint inhibitors have shown significant antitumor activity in melanoma. However, previous randomized trials have excluded patients with untreated brain metastases due to concerns...

Quick Take: Phase Ib/II Study of Pembrolizumab and Pegylated Interferon Alfa-2b in Advanced Melanoma

Programmed death-1 (PD-1) inhibitors have shown efficacy in the treatment of melanoma. Pre-existing CD8+ T-cell infiltrate and interferon (IFN) gene signature has been shown...

Comparative analysis of wounds from oral mucosa versus skin reveals novel therapeutic targets for...

1. Comparative profiling of wounds induced in the oral mucosa versus skin revealed expression of genes that prime the oral mucosa for wound healing....

Early endovenous ablation of leg ulcers improves healing: The EVRA trial

1. Patients with leg ulcers caused by superficial venous reflux treated with compression therapy experienced earlier time to healing if they were treated with...
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