Autologous stem-cell transplantation improves survival in scleroderma patients: The SCOT trial

1. Scleroderma patients treated with myeloablative autologous stem-cell transplantation experienced significantly higher rates of disease-free survival at 52 months post-treatment compared to those treated...

Herpes zoster subunit vaccine may be more cost-effective than live attenuated zoster vaccine

1. The new adjuvanted herpes zoster subunit vaccine was more efficacious and less expensive for all ages at the price of $280 per series...

Despite improving trends in lupus-related mortality, rates appear to remain high relative to non-lupus...

1. Over the 46-year study period, systemic lupus erythematosus (SLE) age-standardized mortality rates (ASMRs) did not decline as much as non-SLE ASMR, and there...

Complete dissection does not increase survival for sentinel-node positive melanoma patients

1. Patients with melanoma and positive sentinel lymph-nodes treated with immediate completion lymph-node dissection did not have increased melanoma related survival at three years...

Tofacitinib may be an effective treatment for nail psoriasis

1. In a posthoc analysis of 2, phase 3 randomized controlled trials of over 1000 patients with moderate-to-severe plaque psoriasis, tofacitinib (an oral Janus...

New prevalence estimates for hidradenitis suppurativa in the United States

1. In a population-based analysis of over 48 million records in the United States (US), the overall prevalence of hidradenitis suppurative (HS) was 0.10%. 2....

Long-term use of apremilast for psoriasis associated with an acceptable safety profile

1. In a prospective observational study of over 1100 patients with moderate to severe plaque psoriasis, long-term use (≥156 weeks) of apremilast was not...

Individualized screening for diabetic retinopathy with fundoscopy and HbA1c

1. Risk of developing clinically significant diabetic retinopathy or macular edema over specified timeframes can be modeled using fundal exam and hemoglobin A1c (HbA1c)...

Risankizumab more effective than ustekinumab for moderate-to-severe psoriasis

1. Risankizumab was associated with a significantly greater improvement in the primary endpoint of ≥90% reduction of the Psoriasis Area and Severity Index (PASI)...

Long term phototherapy can enhance treatment response in vitiligo

1. Examination of prospective studies found that a majority of patients with vitiligo had at least 25% re-pigmentation in response to phototherapy, with rates...
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