Optimizing organ donations from overdose deaths may help address national organ shortage
1. U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from organs donated by ODDs...
Medicare pre-ESRD care results in more dialysis initiation but also increased two-year mortality
1. Veterans receiving pre-end stage renal disease (ESRD) nephrology care in under the Medicare system were more likely to undergo dialysis and had a...
Barber facilitated health promotion reduces blood pressure among black male barber patrons
1. Non-Hispanic black male barber patrons prescribed antihypertensive therapy with barber encouragement along with lifestyle modification experienced greater reductions in blood pressures compared to...
Nivolumab plus ipilimumab improve survival in advanced renal cell carcinoma
1. Amongst patients with advanced renal-cell carcinoma and an intermediate or poor prognosis, nivolumab plus ipilimumab was superior to sunitinib alone in improving overall...
HCV-infected kidney donors could save lives
1. No HCV infection was detected in patients receiving HCV-infected kidneys 12 weeks following treatment.
2. No antiviral treatment-related complications occurred recipients of HCV-infected kidneys.
Evidence...
Hydrocortisone plus fludrocortisone decreases mortality in adults with septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality...
Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The...
1. Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared to normal...
No effect of crystalloid type on in-hospital death and length of stay in non-critically...
1. Patients treated with either balanced crystalloids or normal saline did not differ in number of hospital-free days alive after their emergency department visit.
2....
Meropenem-vaborbactam non-inferior to piperacillin-tazobactam for complicated urinary tract infections: The TANGO I trial
1. In this randomized controlled trial, meropenem-vaborbactam was found to be non-inferior to piperacillin-tazobactam for treating complicated urinary tract infections (UTIs).
2. The rate of...
Vegetation size greater than 10 mm associated with increased risk of mortality in infective...
1. In this systematic review and meta-analysis, patients with infective endocardititis with vegetations greater than 10mm in size had significantly increased risk of systemic...
