Nephrology

Reports of high-impact nephrology studies by medical professionals

Tolvaptan reduces eGFR decline in patients with polycystic kidney disease

1. Estimated glomerular filtration rate (eGFR) declined less over one year of treatment for patients with later-stage autosomal dominant polycystic kidney disease (ADPKD) taking...

Heart failure readmission prevention program may have inadvertent consequences

1. In this interrupted time-series and survival analysis, rates of readmission after heart failure hospitalization decreased significantly after the implementation of the Hospital Readmission...

ACE-inhibitors and statins do not impact albuminuria in adolescents with type 1 diabetes mellitus:...

1. In adolescents with type 1 diabetes mellitus, the albumin-to-creatinine ratio was not significantly changed by angiotensin-converting-enzyme (ACE) inhibitors alone, statins alone, or the...

Despite improving trends in lupus-related mortality, rates appear to remain high relative to non-lupus...

1. Over the 46-year study period, systemic lupus erythematosus (SLE) age-standardized mortality rates (ASMRs) did not decline as much as non-SLE ASMR, and there...

Only a small fraction of diabetes cases go undiagnosed

1. Undiagnosed diabetes was more common in overweight or obese adults, older adults, racial and ethnic minorities, and patients lacking health insurance. 2. The majority...

Lifestyle factors important in subsequent cardiovascular risk for women with gestational diabetes

1. In this prospective cohort study, history of gestational diabetes (GDM) was associated with increased risk of cardiovascular disease (CVD) later in life. 2. After...

Tool may help accurately predict 30-day mortality for emergency department patients with acute heart...

1. Based on 13 independent risk factors that are available at most emergency department (ED) admissions, the MEESSI-AHF (Multiple Estimation of risk based on...

Intensive blood pressure lowering linked to decreased mortality in patients with chronic kidney disease

1. In a meta-analysis of randomized trials evaluating blood pressure control in patients with stage 3-5 chronic kidney disease (CKD), more intensive blood pressure...

Cardiovascular benefits of intensive systolic blood pressure control may outweigh risks of chronic kidney...

1. The benefits of intensive systolic blood pressure (SBP) control to cardiovascular and all-cause mortality may outweigh the increased risk of incident chronic kidney...

Risk of cardiovascular events similar between degludec and glargine in type 2 diabetics: The...

1. Type 2 diabetic patients at high-risk for cardiovascular events treated with the ultra long-acting insulin degludec experienced cardiovascular events at an incidence noninferior...
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