Nephrology

Reports of high-impact nephrology studies by medical professionals

Brain Natriuretic Peptide for predicting prognoses in patients with worsening renal function and acute...

1. The reduction in Brain Natriuretic Peptide, in conjunction with worsening renal failure, can predict prognosis of patients with acute heart failure Evidence Rating: 2...

Kidney function in type 1 diabetes does not benefit from allopurinol therapy

1. Serum urate reduction with allopurinol was not shown to clinically benefit kidney function among patients with type 1 diabetes and early-to-moderate diabetic kidney...

Proton pump inhibitor use associated with increased mortality risk in kidney transplant patients

1. PPI use may be associated with an increased mortality risk in patients who have received kidney transplants. Evidence Rating Level: 1 (Excellent) Proton-pump inhibitors (PPIs)...

Allopurinol does not slow eGFR decline for chronic kidney disease

1. Urate reduction with allopurinol did not slow the decline of estimated glomerular filtration rate (eGFR) compared to the placebo treatment in patients with...

Bariatric surgery and long-term survival in patients with obesity and end-stage kidney disease

1. Bariatric surgery for patients with obesity and end-stage kidney disease was associated with lower all-cause mortality at 5 years. Evidence Rating: 2 (Good) Obesity...

Gastric bypass surgery more effective than medical therapy alone for achieving microalbuminuria remission in...

1. Patients who underwent Roux-en-Y gastric (RYGB) surgery had higher rates of microalbuminuria remission when compared to those who received only medical treatment at...

Long-term use of rituximab associated with lower rates of AAV relapse

1. In this randomized controlled trial involving patients with antineutrophil cytoplasmic antibody-associated vasculitis in complete remission, administration of rituximab for an additional 18 months...

Antihypertensive medications and risk of COVID-19

1. Amongst the five examined classes of antihypertensive medications (ACE Inhibitors, ARBs, beta blockers, calcium-channel blockers, and thiazide diuretics), none were associated with a...

Error in GFR calculation with exclusion of patient race

1. The exclusion of patient race from glomerular filtration rate (GFR) estimation resulted in systematic error that significantly underestimated GFR in African American individuals...

Febuxostat not effective at delaying progression of carotid atherosclerosis in asymptomatic hyperuricemia

1. While there was no placebo control group, treatment with febuxostat for 24 months did not slow carotid atherosclerosis progression in Japanese individuals with...
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