Nephrology

Reports of high-impact nephrology studies by medical professionals

Renin-angiotensin inhibitors may reduce mortality and heart failure readmissions in patients with transcatheter aortic...

1. In this retrospective cohort study of transcatheter aortic valve replacement (TAVR) patients, Renin-Angiotensin System (RAS) inhibitors administered at hospital discharge reduced mortality and...

Interpreting genetic variants in kidney and genitourinary disorders will likely require systematic curation of...

1. This secondary analysis of genetic data emphasized the high number of potentially “pathogenic” variants that are revealed through exome sequencing when analyzing a...

Quick Take: Intravenous Iron in Patients Undergoing Maintenance Hemodialysis

Patients undergoing hemodialysis typically receive intravenous iron, despite a lack of established clinical efficacy. In this randomized controlled trial, investigators randomized 2141 patients undergoing...

Angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use linked with decreased mortality after inpatient...

1. In this retrospective cohort study looking at patients admitted to hospital with acute kidney injury, use of angiotensin-converting enzyme inhibitor or angiotensin receptor...

Intensive blood pressure lowering favored to not induce kidney disease, contrary to prior research

1. Patients managed with intensive blood pressure reduction were found to have significantly greater decreases in kidney damage biomarkers compared to standard blood pressure...

Early and delayed renal-replacement therapy for septic shock associated acute kidney injury show similar...

1. Among patients with septic shock and acute kidney injury (AKI), there was no significant difference in 90-day mortality between early (within 12 hours)...

Lower patient satisfaction reported at for-profit dialysis centers

1. Patient reported experience has recently been incorporated into Quality Incentive Programs for dialysis centers across the United States. Lower patient experience scores were...

Patisiran is effective in treatment of hereditary transthyretin amyloidosis.

1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 months of use.2. Types...

Extreme preterm birth linked to hypertension at school age

1. Within a cohort of infants born extremely preterm (EPT), there were elevated rates of high systolic blood pressure (SBP≥90%ile) and hypertension (SBP≥95%ile) when...

Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients...

1. Use of HCV-infected kidneys increased patients’ quality-adjusted life expectancy.2. Lower costs were associated with HCV-infected kidneys compared to transplanting HCV-uninfected kidneys to HCV-positive...

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