Nephrology

Reports of high-impact nephrology studies by medical professionals

Poor humoral response observed in patients undergoing hemodialysis following a single dose of the...

1. The findings of this prospective cohort study suggested poor humoral immune response following a single dose of the BNT162b2 COVID-19 vaccine in the...

7-day antibiotic therapy is noninferior to 14-day therapy in afebrile men with urinary tract...

1. A double-blinded, randomized controlled trial found that there were no significant differences between afebrile men treated for 7 days versus 14 days of...

Impact of point-of-care screening for hypertension, diabetes, and progression of chronic kidney disease in...

1. Point of care screening interventions lead to higher frequency of comprehensive lab testing, medication prescriptions, and nephrology follow up visits.  2. In rural and...

Daratumumab therapy addition improved response in systemic immunoglobulin light-chain amyloidosis

1. Daratumumab therapy addition to bortezomib, cyclophosphamide, and dexamethasone showed improved cancer response in patients with systemic immunoglobulin light-chain amyloidosis. 2. The daratumumab group presented...

Voclosporin shows clinical promise for treatment of active lupus nephritis

1. A significantly greater proportion of patients in the voclosporin group achieved complete renal responses after 52 weeks compared to the placebo group. 2. The...

Reduced-dose glucocorticoid adjunct non-inferior to high-dose glucocorticoid plus rituximab regimen for induction of disease...

1. Reduced-dose glucocorticoid plus rituximab regimen was non-inferior compared to high-dose glucocorticoid plus rituximab regimen for induction of disease remission in ANCA-associated vasculitis  Evidence Rating...

Risk factors for acute kidney injury and mortality in high risk patients undergoing cardiac...

1. In a retrospective cohort study, several pre-operative and operative factors were found to be associated with acute kidney injury and future mortality. Evidence...

Normotensive patients with elevated cardiovascular risk may benefit from antihypertensive pharmacotherapy

1. Regardless of cardiovascular disease history and baseline blood pressure, a 5 mmHg reduction in systolic blood pressure reduced relative risk of major cardiovascular...

Routine urinary tract cancer testing among all patients with microhematuria has low diagnostic yield

1. Evaluation with cystoscopy and CT urography for patients presenting with microhematuria (MH) had a low diagnostic yield for urinary tract cancers. 2. The diagnostic...

Lumasiran decreases urinary oxalate excretion in Primary Hyperoxaluria Type 1

1. Lumasiran was shown to decrease urinary oxalate excretion in patients with Primary Hyperoxaluria Type 1. 2. Lumasiran was shown not to cause severe or...

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