Patisiran is effective in treatment of hereditary transthyretin amyloidosis.
1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 months of use.
2. Types...
Extreme preterm birth linked to hypertension at school age
1. Within a cohort of infants born extremely preterm (EPT), there were elevated rates of high systolic blood pressure (SBP≥90%ile) and hypertension (SBP≥95%ile) when...
Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients...
1. Use of HCV-infected kidneys increased patients’ quality-adjusted life expectancy.
2. Lower costs were associated with HCV-infected kidneys compared to transplanting HCV-uninfected kidneys to HCV-positive...
Nonsurgical treatment of small tumor renal cancer may be as effective as radical nephrectomy...
1. Rates of renal insufficiency were highest in patients receiving renal nephrectomy, compared to less invasive treatments.
2. Survival rates for renal nephrectomy and partial...
Restricting perioperative fluid for abdominal surgery patients does not reduce complications: The RELIEF trial
1. Among patients at increased risk for complications undergoing abdominal surgery, those randomized to perioperative fluid restriction did not have increased disability-free survival at...
Improved calculations suggest major changes to statin, aspirin, and blood pressure medication prescribing
1. Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.
2. Many Americans, especially those of African American...
Physicians report feeling moral distress over hospital policies that force inadequate care based on...
1. Physicians working in settings that provide emergency only hemodialysis (EOHD) reported higher rates of professional burnout.
2. Physicians providing EOHD reported feeling moral distress...
Coaching to improve water intake does not improve kidney function in adults with chronic...
1. In this randomized controlled trial, coaching to improve daily fluid intake did not improve kidney function in patients with Chronic Kidney Disease.
2. Increasing...
Hospice care may not decrease Medicare costs in patients on maintenance dialysis
1. In this cross-sectional study, of those patients on maintenance hemodialysis that were referred to hospice care, 41.5% received care for only 3 days...
Smartphone medication adherence application did not improve systolic blood pressure
1. In this randomized controlled trial, there was no significant difference in systolic blood pressure across participants that used the Medisafe app for blood...
