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Melatonin use is associated with lower proportions of rapid eye movement sleep in children
1. In an observational study of pediatric patients, melatonin use may be associated with a decreased percentage of rapid eye...
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Tumour microenvironment factors may influence cancer progression and response to tamoxifen (Nolvadex) in patients with estrogen receptor-positive and human epidermal growth factor receptor 2 breast cancer
1. In patients with estrogen receptor (ER)+ and human epidermal growth factor receptor 2 (HER2)- breast cancer, certain tumour microenvironments...
Antithrombotic agents may be effective in preventing migraine in patients with patent foramen ovale
1. The antithrombotic agents aspirin, clopidogrel, and rivaroxaban were non-inferior to metoprolol for responder rate in participants with patent foramen...
Praziquantel (Biltricide) is associated with higher cure rate than albendazole (Zentel) in the treatment of clonorchiasis
1. In the treatment of Clonorchis sinensis, albendazole (Zentel) demonstrates a high egg reduction rate but a significantly lower cure...
Use of semaglutide for weight control among women of reproductive age is more common in those using hormonal contraception
1. Among a nested case-control study, use of hormonal contraception was associated with higher subsequent semaglutide initiation for weight control...
Medical or procedural abortion may not increase risk of psychotropic medication use after five years
1. Among a Danish population-based cohort study, increased initiation of psychotropic medication in the first year following both medical and...
Epidural analgesia in labour is not associated with adverse neonatal health outcomes
1. Epidural analgesia in labour is not associated with significant risk of neonatal neurological morbidity, neonatal morbidity or mortality. Evidence...
Cefazolin non-inferior to penicillins for methicillin-susceptible Staphylococcus aureus bacteremia
1. In this international randomized controlled trial of adults with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, cefazolin was noninferior to antistaphylococcal...
All-oral chemotherapy regimen tolerable and efficacious for newly diagnosed acute myeloid leukemia
1. In this phase 1-2 trial involving patients with newly diagnosed acute myeloid leukemia who were ineligible for intensive chemotherapy,...
Enzalutamide (Xtandi) and abiraterone (Zytiga) may have similar effectiveness in metastatic castration-sensitive prostate cancer
1. The use of enzalutamide (Xtandi) and abiraterone (Zytiga) in metastatic castration-sensitive prostate cancer (mCSPC) was associated with similar overall...
