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Tarlatamab in Small-Cell Lung Cancer after Platinum-Based Chemotherapy
1. Median overall survival was 13.6 months in the tarlatamab group and 8.3 months in the chemotherapy group, with HR...
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Perioperative Durvalumab in Gastric and Gastroesophageal Junction Cancer
1. Event-free survival at 24 months was 67.4% in the durvalumab group and 58.5% in the placebo group, with HR...
Nivolumab plus ipilimumab improves survival over lenvatinib or sorafenib in liver cancer
1. Median overall survival was 3.1 months greater in the nivolumab plus ipilimumab group. 2. Grade 3-4 treatment-related adverse events...
Sacituzumab tirumotecan may have a role in the treatment of metastatic non-small cell lung cancer
1. In patients with previously treated metastatic epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC), treatment with sacituzumab...
Birth cohort effects observed for increased appendiceal adenocarcinoma incidence
1. In this retrospective cohort study, age-specific incidence rates of appendiceal adenocarcinoma increased by time period. 2. Local drift for...
Artificial Intelligence Model Matches Patients to Clinical Trials with Near Human Accuracy
Key points:1. TrialGPT, developed by the National Institutes of Health, matches patients to clinical trials with 87.3 percent accuracy2. Clinicians...
Physical disability and psychological distress demonstrate marked progression after diagnosis of cancer
1. In this Australian cohort of adults, individuals diagnosed with cancer experienced greater declines in physical functioning and slightly higher...
Becton Dickinson Unveils Artificial Intelligence Powered Monitor for Surgery
Key points:1. The HemoSphere Alta system from Becton Dickinson uses artificial intelligence to predict blood pressure drops during surgery2. Early...
Artificial Intelligence and Real World Data Speed Up Drug Development
Key points:1. TriNetX is using real world data to reduce clinical trial enrollment time by as much as 40 percent2....
Food and Drug Administration to Fully Integrate Generative Artificial Intelligence by June
Key points:1. The Food and Drug Administration is preparing to launch an agency wide generative artificial intelligence system by the...