Risk of autism in offspring linked to maternal pregestational diabetes and severe obesity
1. Maternal prepregnancy obesity without pregestational diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) was associated with a slightly increased risk of having a...
Anastrazole superior to tamoxifen for breast cancer treatment [Classics Series]
1. Postmenopausal women with advanced breast cancer randomized to anastrazole as first-line therapy experienced an increase in time to progression and a more favorable...
Mean platelet counts shown to decrease during pregnancy
1. Retrospective analyses demonstrated evidence of mean platelet count decline during pregnancy beginning as early as the first gestational trimester
2. Platelet counts were significantly...
Primary HPV testing may detect cervical neoplasms earlier and more accurately than cytology
1. In this Canadian, randomized controlled trial, the use of primary HPV testing compared with cytology resulted in a significantly lower likelihood of CIN3+...
Women who experience hypertensive disorders during pregnancy are at high risk for developing high...
1. Women experiencing hypertensive disorders of pregnancy (HDP) had higher rates of cardiovascular disease persisting following the pregnancy.
2. Women with HDP were at particular...
Prenatal antidepressant exposure may increase risk of poor motor development
A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse...
Lower and higher oxygen saturation targets result in equal but contrasting outcomes for extremely...
1. In this meta-analysis, there was no significant difference between lower and higher oxygen saturation targets on a primary composite of mortality or major...
Adolescent mothers in protective care more likely to have their children placed in care
1. Children born to adolescent mothers in the care of child protection services (CPS) were more likely to be taken into CPS care themselves...
Acupuncture does not improve the rate of live births among women undergoing in vitro...
1. In this randomized controlled trial, administration of acupuncture at the time of ovarian stimulation and embryo transfer did not improve the rate of...
Glyburide is not non-inferior to insulin in reducing perinatal complications in gestational diabetes
1. In this randomized controlled trial, glyburide was not non-inferior in terms of the composite rate of macrosomia, neonatal hypoglycemia, and hyperbilirubinemia compared with...
