Relugolix combination therapy led to reduction in uterine fibroid symptoms
1. Once-daily relugolix combination therapy resulted in a significant reduction in heavy menstrual bleeding compared with placebo in women with uterine fibroids.
2. The combination...
Higher SARS-CoV-2 infection rate in pregnant patients
1. In Washington State, pregnant patients were found to be at a higher risk of SARS-CoV-2 infection.
2. Results were more pronounced if patients belonged...
Maternal chronic conditions increase risk of cerebral palsy among offspring
1. Maternal chronic conditions (particularly autoimmune conditions) such as type 1 and 2 diabetes, rheumatoid arthritis, and migraines were associated with a higher risk...
Use of opioids in first trimester not associated with greater risk of congenital malformations
1. The use of opioid medications during the first trimester is not significantly associated with greater risk of congenital malformations.
2. Following adjustments, opioid use...
Pregnancy outcomes in women with moderate-to-severe psoriasis
1. Pregnant women using biologic treatments for psoriasis, both before and during pregnancy, were found to have similar pregnancy outcomes as the general American...
Improved contraception use with progestogen-only pill and rapid access vs emergency contraception
1. Compared to emergency contraception alone, continued use of effective contraception was 20.1% greater among women provided with a 3-month supply of progestogen-only pills...
Association between maternal breastfeeding satisfaction and postpartum depression
1. Increased breastfeeding satisfaction was 47% higher among mothers who were negative for postpartum depression compared to those who were positive for postpartum depression.
Evidence...
Prevalence of suicidality significantly increased over 12-year period among childbearing persons
1. Prevalence of suicidality increased significantly over a 12-year period among childbearing persons.
2. The prevalence of suicidality with comorbid depression or anxiety increased significantly...
Post-extubation high-flow nasal cannula associated with higher rates of treatment failure in preterm infants
1. Rate of treatment failure within 7 days of extubation was higher in patients that received post-extubation high-flow nasal cannula (HFNC), as compared to...
Decision aid tools helpful in resolving decision conflict for patients contemplating epidural anesthesia during...
1. A decision aid tool significantly helped resolve decision conflict in patients contemplating the use of epidural anesthesia during labour.
Evidence Rating Level: 1 (Excellent)
In...
