Obstetrics

Reports of high-impact obstetrics and gynecology studies by medical professionals

Quick Take: Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES)

Studies have shown that intrahepatic cholestasis of pregnancy is associated with poor birth outcomes and neonatal unit admission. Ursodeoxycholic acid, which increases bile acid...

Quick Take: Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe...

Hypertension commonly affects women in pregnancy, and is associated with adverse effects for both mother and baby. Currently, there is a lack of consensus...

Racial, ethnic differences in outcomes of extremely preterm infants decreasing but persistent

1. In this retrospective cohort study reviewing data from 2006 to 2017, researchers showed very premature infants identified as African American had more rapid...

Quick Take: Overall survival with ribociclib plus endocrine therapy in breast cancer

Hormone therapy is the standard of care for premenopausal and postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor2 (HER2)-negative advanced breast cancer....

Challenges and feasibility of fertility preservation in feminizing transgender youth

1. In this retrospective cohort study, fertility preservation proved feasible in transgender feminizing youth, both before and after the initiation of gender-affirming hormonal therapies.2....

Trends in systemic lupus erythematosus pregnancy outcomes in the United States

1. In this retrospective cohort study, the authors observed that the greater decline in in-hospital maternal mortality was found for systemic lupus erythematosus (SLE)...

Quick Take: Investigating causal relations between sleep traits and risk of breast cancer in...

Previous studies have provided evidence for an association between circadian disruption and breast cancer risk. However, studies examining sleep traits such as chronotypes, insomnia...

Quick Take: HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine...

Previous studies have suggested that certain hormonal contraceptive methods, including intramuscular depot medroxyprogesterone acetate (DMPA-IM), may increase women’s susceptibility to HIV acquisition. In this...

Being denied a wanted abortion may have detrimental health effects in the long term

1. The authors of this prospective cohort study found that women who were denied a wanted abortion were found to have higher rates of...

Lisinopril and carvedilol reduce cardiotoxicity in breast cancer patients receiving trastuzumab and anthracyclines

1. In this randomized, placebo controlled study of HER2-positive breast cancer patients receiving trastuzumab, use of preventative lisinopril or carvedilol did not significantly reduce...
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