Low-dose intracoronary alteplase unlikely to improve outcomes in STEMI patients treated with primary PCI

1. In this randomized controlled trial, low-dose intracoronary alteplase given early during primary percutaneous coronary intervention (PCI) for acute ST-Elevation Myocardial Infarction (STEMI) did...

Cardiac troponin elevation without definitive diagnosis associated with higher mortality

1. Among patients admitted for suspected acute coronary syndrome but discharged without a specific diagnosis, higher cardiac troponin levels were associated with elevated all-cause...

Aspirin alone likely safest antithrombotic therapy after bioprosthetic aortic valve replacement

1. Aspirin combined with warfarin was linked with increased bleeding but not less thromboembolism compared with aspirin alone after bioprosthetic aortic valve replacement.2. Dual...

Risk of lifetime stroke exhibits notable geographic variation

1. The 2016 Global Burden of Disease Survey data was assessed to evaluate lifetime risk of stroke in numerous countries and territories, providing global...

Quick Take: Sex and Race Differences in the Association of Incident Ischemic Stroke with...

There are large differences in the incidence of stroke among various ethnic groups, as well as between sexes. These differences also vary significantly with...

Quick Take: Christmas, National Holidays, Sport Events, and Time Factors as Triggers of Acute...

Ischemic heart disease, the most common cause of morbidity and mortality worldwide, has many modifiable and non-modifiable risk factors, including several external factors. This...

Data supports limiting blood transfusions for moderate anemia

1. The authors observed in this retrospective cohort study that transfusion rates decreased among patients from 2010 and 2014.2. Paralleling decreasing transfusion rates, the...

Targeted electronic health record reminder can reduce telemetry duration

1. In this study, a targeted electronic health record (EHR) reminder of telemetry-use beyond that recommended by guidelines resulted in the reduction of telemetry...

Lanadelumab may be an effective prophylactic treatment for hereditary angioedema

1. In this randomized controlled trial, prophylactic lanadelumab reduced attack frequency and severity in patients with hereditary angioedema compared to placebo.2. The most common...

Large spike in drug use-associated infective endocarditis linked with opioid epidemic

1. Researchers have identified a significant increase in hospitalizations due to infective endocarditis related to drug use.2. Heart valve surgeries among patients with drug...

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