No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography: The...

1. Amongst patients undergoing angiography, neither sodium bicarbonate nor acetylcysteine were effective in preventing a composite outcome of death, need for dialysis, or persistent...

Pulmonary Embolism Rule-out Criteria non-inferior to usual care for patients at low-risk for pulmonary...

1. In this multicenter, randomized controlled study, the Pulmonary Embolism Rule-out Criteria (PERC) was not associated with an inferior rate of diagnosing thromboembolic events...

Quality of care for transient ischemic attack and minor stroke vary across country

1. In this study about quality of care for patients with TIA or minor stroke, there was substantial variation in adherence to guidelines for...

ICD placement in CKD patients increases hospitalizations without survival benefit

1. Adults with chronic kidney disease (CKD) and heart failure with reduced LVEF who received implantable cardioverter defibrillators (ICDs) did not differ from matched...

Prazosin and placebo exhibit similar efficacy in post-traumatic stress disorder: The PACT trial

1. In patients with nocturnal symptoms of post-traumatic stress disorder (PTSD), prazosin did not significantly reduce nightmares or improve quality of sleep compared to...

Preoperatively diagnosed patent foramen ovale linked to increased perioperative stroke risk

1. A preoperatively diagnosed patent foramen ovale was associated with an increased risk of stroke within 30 days of non-cardiac surgery. Evidence Rating Level: 2...

Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure...

1. For predicting short-term mortality in patients with suspected infection, quick Sequential Organ Failure Assessment (qSOFA) had moderate specificity and poor sensitivity. 2. The systemic...

Low prevalence of pulmonary embolism among patients with syncope

1. Based on this retrospective cohort study from multiple countries, the prevalence of pulmonary embolism among patients presenting to the emergency department (ED) with...

Pharmacist-led extended medication review and follow-up on discharge may decrease risk of readmission

1. In this randomized clinical trial, a pharmacist-led extended intervention, which included medication review, three motivational interviews, and telephone follow-up resulted in significant decreases...

Catheter ablation of atrial fibrillation in heart failure reduces mortality and hospitalization: The CASTLE-AF...

1. Compared to medical therapy alone, catheter ablation of atrial fibrillation in patients with heart failure reduced the risk of all-cause mortality and hospitalization. 2....
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