ICU admissions among Medicare beneficiaries on a decade-long downward trend
1. Intensive care unit (ICU) admission rates decreased from 2006 to 2015.
2. No association was found between percentage change in ICU beds and admissions...
Polymyxin B hemoperfusion unlikely to reduce mortality for sepsis
1. In this randomized controlled trial, hemoperfusion with polymyxin B resulted in similar 28-day mortality compared to sham hemoperfusion for patients with sepsis with...
Acetaminophen reduces recurrence of febrile seizures in children within same fever episode
1. Rectal acetaminophen reduces rates of second febrile seizure (FS) in children during the course of the same febrile illness when given rectally soon...
Transcranial direct current stimulation linked to improved object naming post-stroke
1. In this randomized trial of patients with aphasia, use of anodal transcranial direct current stimulation (A-tDCS) demonstrated improved object naming compared to sham...
Supraglottic airway resuscitation likely more or just as effective as endotracheal intubation for out-of-hospital...
1. In an American, randomized controlled trial, supraglottic airway (SGA) resuscitation was associated with marginally better neurological outcomes and 72-hour survival compared to endotracheal...
Clinical guidelines may lead to better prescribing practices
1. Following clinical guidelines release, decreases were observed in the overall rate of opioid prescribing.
2. Guidelines may be associated with reduced high-dosage opioid prescriptions...
Pregabalin may increase the risk of death when coprescribed with opioids
1. Patients coprescribed opioids and pregabalin had significantly increased odds of opioid-related death compared to opioid prescription alone.
2. More than half of Ontario residents...
Pre-hospital plasma transfusion in patients at risk of hemorrhagic shock decreases mortality
1. In patients at risk of hemorrhagic shock, the pre-hospital administration of thawed plasma decreased mortality at 24 hours and 30 days and patients...
Mean platelet counts shown to decrease during pregnancy
1. Retrospective analyses demonstrated evidence of mean platelet count decline during pregnancy beginning as early as the first gestational trimester
2. Platelet counts were significantly...
Alteplase unlikely to reduce disability after mild stroke without disabling deficits
1. In this randomized controlled trial, administration of alteplase within 3 hours of mild stoke did not lead to a reduction in disability at...
