Steroids and opioids often inappropriately prescribed in the emergency department for pediatric pneumonia and...

1. In a study of children with pneumonia or sinusitis, opioids and corticosteroids were inappropriately prescribed more frequently in the emergency department (ED) for...

SARS-CoV-2 may be more transmissible than SARS-CoV and Middle Eastern respiratory syndrome coronavirus

1. SARS-CoV-2 is more transmissible in households compared to SARS-CoV and MERS-CoV. 2. Individuals aged over 60 years were the most susceptible to household transmission...

Prone positioning in non-intubated COVID-19 patients with acute respiratory failure may transiently improve blood...

1. Non-intubated patients with COVID-19-related pneumonia had substantial, yet non-sustained, improvements in their PaO2/FiO2 ratio by over 50% after 10 minutes of prone positioning. 2....

Budesonide triple therapy significantly lowers exacerbation rates in severe COPD

1. Triple therapy for severe chronic obstructive pulmonary disease (COPD) with budesonide-glycopyrrolate-formoterol was associated with significantly lower risk of COPD exacerbation compared to dual...

TICO Trial: Ticagrelor monotherapy vs. extended dual anti-platelet therapy after placement of drug-eluting stents...

1. Patients status-post placement of drug-eluting stents (DES) for acute coronary syndrome received three months of Ticagrelor and Aspirin dual-antiplatelet therapy (DAPT), followed by...

Co-prescription of clarithryomycin with direct oral anticoagulants associated with increased bleed risk.

1. Co-prescription of clarithromycin and direct oral anticoagulants was associated with a higher rate of 30-day hospitalization with hemorrhage when compared with co-prescription of...

Migraines during pregnancy and the risk of maternal stroke

1. Women with migraines are at an increased risk of stroke during and after pregnancy compared to those without migraines. Evidence Rating Level: 2...

Intra-arterial thrombectomy is associated with improved functional outcomes in stroke patients

1. Stroke patients who received endovascular treatment plus standard medical treatment in the public care system in Brazil showed significantly less severe disability at...

Migraines with aura linked to increased cardiovascular disease risk in women

1. In this cohort of women, those who experienced migraines with aura were associated with an increased adjusted incidence rate for major cardiovascular diseases...

Carotid endarterectomy vs initial medical therapy in asymptomatic carotid stenosis

1. Absolute risk reduction of stroke in asymptomatic carotid stenosis was significantly lower than it was two decades ago. 2. Advances in stroke prevention suggest...
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