Peripheral perfusion-targeted resuscitation does not lower mortality in septic shock patients

1. In this randomized controlled trial, there was no difference in 28-day mortality in patients with early septic shock between peripheral perfusion-targeted resuscitation and...

The PIONEER-HF Trial: Sacubitril-valsartan linked to superior outcomes in acute decompensated heart failure

1. Among patients hospitalized for acute decompensated heart failure with reduced ejection fraction (HFrEF), treatment with sacubitril-valsartan reduced N-terminal pro-B type natriuretic peptide (NT-proBNP)...

Quick Take: Impact of scribes on emergency medicine doctors’ productivity and patient throughput: multicentre...

Medical scribes are used in variety of clinical settings to complete clerical tasks otherwise done by a clinician. Limited research has been done concerning...

Individualized exercise program linked to faster recovery following pediatric sport-related concussion

1. In this randomized control trial of pediatric sport-related concussion (SRC), a progressive sub-symptom threshold aerobic exercise program was linked to a shorter time...

Aspirin use associated with reduction in cardiovascular events but increase in bleeding risk

1. In this systematic review and meta-analysis, while aspirin use among patients without cardiovascular disease was associated with fewer adverse cardiovascular events, it was not...

Low-dose intracoronary alteplase unlikely to improve outcomes in STEMI patients treated with primary PCI

1. In this randomized controlled trial, low-dose intracoronary alteplase given early during primary percutaneous coronary intervention (PCI) for acute ST-Elevation Myocardial Infarction (STEMI) did...

Cardiac troponin elevation without definitive diagnosis associated with higher mortality

1. Among patients admitted for suspected acute coronary syndrome but discharged without a specific diagnosis, higher cardiac troponin levels were associated with elevated all-cause...

Aspirin alone likely safest antithrombotic therapy after bioprosthetic aortic valve replacement

1. Aspirin combined with warfarin was linked with increased bleeding but not less thromboembolism compared with aspirin alone after bioprosthetic aortic valve replacement.2. Dual...

Risk of lifetime stroke exhibits notable geographic variation

1. The 2016 Global Burden of Disease Survey data was assessed to evaluate lifetime risk of stroke in numerous countries and territories, providing global...

Quick Take: Sex and Race Differences in the Association of Incident Ischemic Stroke with...

There are large differences in the incidence of stroke among various ethnic groups, as well as between sexes. These differences also vary significantly with...
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