Carriers of genetic variants of inherited cardiomyopathies and arrhythmias associated with unexplained sudden cardiac...

1. In this study of White and African American adults who had unexplained sudden cardiac death, nearly 20% of individuals had pathogenic or likely...

Net fluid balance not associated with hospital readmission rates among sepsis patients

1. There was no association found between positive fluid balance at the time of discharge and readmission at 30 days post-discharge in non-critically ill...

Dexamethasone vs methylprednisolone high dose for COVID-19 pneumonia

1. Hospitalized COVID-19 patients receiving high-dose methylprednisolone followed by oral prednisone had improved clinical outcomes compared to patients receiving dexamethasone. Evidence Rating Level: 2 (Good) In...

Continuous infusion of hypertonic saline following traumatic brain injury does not improve neurological outcomes...

1. No significant difference was found in neurological function recovery measured by extended Glasgow scale score in patients with moderate to severe traumatic brain...

Survivors of intensive care unit admissions may have increased risk of self-harm and suicide

1. Patients with prior episodes of critical illness requiring ICU admission were found to have an elevated risk of suicide and self-harm. 2. Suicide and...

Primary trabeculectomy associated with similar outcomes as medical management for advanced glaucoma

1. At 24 months, visual quality of life for patients with advanced open angle glaucoma was similar if treated initially with trabeculectomy or with...

Carriers of truncated variants in filamin C with left ventricular systolic dysfunction associated with...

1. Higher frequencies of malignant ventricular arrhythmia and end-stage heart failure were found among individuals carrying truncating variants of the gene encoding filamin C...

Tocilizumab may improve survival in COVID-19 patients with hypoxia and systemic inflammation 

1. Compared to usual care, fewer patients in the tocilizumab group died within 28 days of randomization. 2. Patients allocated tocilizumab were more likely to...

Prophylactic tranexamic acid prevents significant blood loss after cesarean delivery

1. Prophylactic tranexamic acid treatment was shown to lower the incidence of postpartum hemorrhage in women undergoing cesarean delivery. 2. Tranexamic acid treatment was shown...

Intracerebral hemorrhage may be an independent risk factor for arterial ischemic events

1. Patients with an intracerebral hemorrhage (ICH) had an increased risk of ischemic stroke and myocardial infarction events compared to those without a previous...

All-time hits