Unit-dose packaging of buprenorphine-naloxone associated with reduced pediatric unintentional exposures

1. Pediatric unintentional opioid exposures decreased by more than 75% following the introduction of child-resistant unit-dose packaging (UDP). 2. More than 20% of unintentional buprenorphine-naloxone...

Hospital readmissions occurring within 7 days post-discharge may be more preventable than later readmissions

1. The percentage of preventable early readmissions (within 7 days post-discharge) and late readmissions (between 8 and 30 days post-discharge) were 36.2% and 23.0%,...

In-utero exposure to tenofovir-emtricitabine not associated with higher risk of adverse birth outcomes

1. Pairwise comparisons of tenofovir-emtricitabine and ritonavir-boosted lopinavir (TDF-FTC-LPV/r), zidovudine-lamivudine and ritonavir-boosted lopinavir (ZDV-3TC-LPV/r), and tenofovir-emtricitabine and ritonavir-boosted atazanavir (TDF-FTC-ATV/r) HIV regimens among pregnant...

Sickle cell trait not linked to increased risk of ischemic stroke

1. In this meta-analysis of prospective population-based studies, sickle cell trait (SCT) was not associated with any difference in risk of first ischemic stroke. 2....

Systematic crosschecking between emergency physicians may decrease adverse events

1. In this cluster randomized crossover trial, implementation of a systematic crosschecking program between two emergency physicians significantly reduced the occurrence of adverse events. 2....

Addition of ticagrelor to aspirin significantly increased graft patency after elective CABG

1. In this randomized controlled trial, saphenous vein graft patency after elective CABG was significantly improved in patients treated with ticagrelor plus aspirin versus...

Better UTI resolution with 5-day nitrofurantoin over single-dose fosfomycin

1. In this randomized controlled trial, women with uncomplicated urinary tract infections receiving 5-days of nitrofurantoin experienced increased clinical and microbiologic resolution at 28...

Rustbelt states may have greatest racial disparities between black and white men for firearm...

1. Racial disparities for firearm homicides between black and white males are highest in Illinois, Indiana, Michigan, Missouri, and Pennsylvania, with higher rates for...

Prediction tool for urinary tract infections in preverbal children

1. The study reports the development of a clinical and biochemical prediction tool for assessing the risk of urinary tract infection in preverbal children...

Centrifugal-flow pumps improve complication free survival compared to axial flow-pumps: The MOMENTUM 3 trial

1. Advanced heart failure patients randomized to receive centrifugal-flow pumps demonstrated higher rates of 2-year survival free of disabling stroke or reoperation to remove...
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