Rivaroxaban and warfarin have similar safety and efficacy in mild atrial fibrillation-related ischemic stroke
1. In this randomized controlled trial, rivaroxaban and warfarin were similar in safety and efficacy when used to prevent early recurrence of stroke in...
High recurrence of gastroesophageal reflux disease in patients treated with laparoscopic antireflux surgery
1. Among patients receiving laparoscopic antireflux surgery, 17.7% experienced recurrent GERD requiring medication or secondary antireflux surgery
2. Factors associated with recurrence included older age,...
Outreach efforts improve rates of colon cancer screening
1. This randomized clinical trial showed that among persons aged 50-64 years, mailed outreach invitations offering either fecal immunochemical tests (FIT) or colonoscopies increased...
Physician notification increases patient participation in colorectal cancer screening
1. Providing physicians with a list of patients requiring colorectal cancer screening results in a small but significant increase in patient participation in fecal...
Extensive cancer screening may not improve outcomes for patients with unprovoked venous thromboembolism
1. Although more extensive screening may detect more cases of occult cancer in patients with unprovoked venous thromboembolism (VTE) at the preliminary screening, it...
HCV treatment administered by nonspecialist providers as safe and effective as that provided by...
1. HCV treatment by nurse practitioners and primary care physicians with compact didactic training was found to be equally as effective as specialist treatment.
2....
Homozygous complement component CD55 mutations cause novel gastrointestinal syndrome
1. Researchers used whole-exome sequencing to define the novel CHAPLE syndrome, characterized by a homozygous CD55 mutation with hyperactivation of complement, angiopathic thrombosis, and...
Combination treatment with calcineurin inhibitors and IL-2 enhances transplant survival [PreClinical]
1. Blood from liver transplant patients treated with a calcineurin inhibitor (CNI) showed increased levels of apoptotic regulatory T cells (Tregs) and lower IL-2...
Demand for FMT likely to increase with rise in multiply recurrent C. difficile cases
1. Multiply recurrent Clostridium difficile infection (mrCDI) incidence has increased disproportionately to Clostridium difficile infection (CDI), independent of known risk factors for CDI.
2. There is...
Fecal immunochemical testing demonstrates good diagnostic accuracy for high-risk individuals
1. Meta-analysis of available studies evaluating the use of fecal immunochemical testing (FIT) for colorectal cancer (CRC) in patients at higher than average personal...
