Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Liver fibrosis in post-PCI patients associated with higher incidence of cardiovascular events

1. Post-PCI patients with intermediate to high liver fibrosis scores were observed to experience higher incidences of major cardiovascular events. Evidence Rating Level: 1 (Excellent) While...

Pembrolizumab linked to longer cancer-free period in advanced colon cancer

1. In a phase 3 trial across 23 countries, Pembrolizumab displayed a longer cancer-free period when compared to the first line therapy for metastatic...

Lansoprazole not effective for the treatment of persistent throat symptoms

1. Lansoprazole was not found to be efficacious in the treatment of persistent throat symptoms. Evidence Rating Level: 1 (Excellent) Persistent throat symptoms are frequently encountered...

Adjunctive methylprednisolone treatment for hepatitis B acute-on-chronic liver failure associated with increased survival rate

1. Adding methylprednisolone to standard treatment in hepatitis B virus-related acute-on-chronic liver failure was associated with an increase in 6-month survival rate. Evidence Rating Level:...

Laparoscopic sigmoid resection for recurrent diverticulitis associated with higher quality of life scores

1. Patients with recurrent diverticulitis have higher quality of life scores after undergoing elective laparoscopic sigmoid resection, compared to a conservative treatment. 2. Elective surgery...

No difference in survival after laparoscopic versus open liver resection for colorectal metastases

1. The rates of 5-year overall survival were found to differ by less than a percentage point between patients in the laparoscopic group and...

Semaglutide associated with dose-dependent weight loss and resolution of nonalcoholic steatohepatitis

1. Nonalcoholic steatohepatitis (NASH) resolution without worsening of fibrosis occurred in a significantly greater percentage of patients who received semaglutide versus placebo, but the...

Comparison of life and healthy life expectancies between IBD patients and the general population

1. From 1996 to 2011, life expectancy for IBD patients increased by approximately 3 years, whereas from 1996 to 2008, healthy life expectancy decreased...

Efficacy and safety of short-term therapy with indigo naturalis for ulcerative colitis

1. Short-term indigo naturalis therapy demonstrated symptomatic improvement in patients with mild to moderate ulcerative colitis. Evidence Rating Level: 1 (Excellent) Treatment options for ulcerative colitis...

Lirentelimab may be effective for treatment of eosinophilic gastrointestinal disease

1. Patients who received AK002, lirentelimab, had far greater reductions in both gastrointestinal eosinophil burden and gastrointestinal symptoms compared to those who received placebo. 2....

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