Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Role of endoscopic ultrasonography for differential diagnosis of upper gastrointestinal submucosal lesions

1. In a group of patients with upper gastrointestinal submucosal lesions, endoscopic ultrasonography demonstrated good diagnostic value in specific types of lesions. Evidence Rating Level:...

Incomplete polyp resection increases risk of future and advanced neoplasia

1. Incomplete resection of colon segments was shown to significantly increase the risk of future neoplasia compared to segments with complete resection. 2. Advanced neoplasia...

Ivosidenib improves overall survival in IDH1-mutant advanced cholangiocarcinoma as compared to placebo

1. Patients receiving Ivosidenib had longer overall survival as compared to patients on placebo. 2. Quality of life measures favored Ivosidenib as compared to placebo. Evidence...

Camrelizumab with chemotherapy demonstrated improved overall survival and progression-free survival of esophageal squamous cell...

1. Camrelizumab improved the overall survival and the progression-free survival of esophageal squamous cell carcinoma patients compared to placebo treatment as adjuvants to chemotherapy. 2....

Ranitidine may not lead to significant increase in N-nitrosodimethylamine in healthy adults

1. Ranitidine consumption did not result in higher urinary excretion of N-nitrosodimethylamine (NDMA) compared to placebo. 2. High nitrite diet increased urinary excretion of NDMA. Evidence...

Combination of buprenorphine and naloxone may be safe for those hospitalized with acute hepatitis...

1. This quantitative study found that buprenorphine/naloxone can be safely administered to patients with acute hepatitis A without increased risk of liver problems such...

Evaluation of early vs standard liver transplant for alcohol-associated liver disease

1. In a cohort of patients with alcoholic liver disease, adherence to a 6-month abstinence period prior to liver transplant was not associated with...

Amoxicillin-clavulanate offers similar effectiveness for treating outpatient diverticulitis than metronidazole-with-fluoroquinolone

1. Treatment of outpatient diverticulitis with amoxicillin-clavulanate was shown to be comparably effective as a treatment of metronidazole-with-fluoroquinolone for outpatient diverticulitis. 2. The 1-year risk...

Oral ondansetron administration in children seeking emergency department care for acute gastroenteritis

1. Among a cohort of children with gastroenteritis in the emergency department (ED), administration of oral ondansetron was associated with a reduction in index...

Checkpoint inhibitors show some benefit in patients with microsatellite stable metastatic colorectal cancer without...

1. In this retrospective cohort study investigating targeted therapy of programmed cell death receptor 1 and programmed cell death ligand 1 in the treatment...

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