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Newborn screening for cystic fibrosis improves nutritional outcomes
1. In this retrospective study, newborn screening for cystic fibrosis in the United States lead to improve nutritional status with higher...
Gastroenterology
Reports of high-impact gastroenterology studies by medical professionals
Endoscopic sleeve gastroscopy effective for excess weight loss in type 1 and 2 obesity
1. Approximately three-quarters (77%) of patients who underwent endoscopic sleeve gastroscopy with lifestyle modifications achieved 25% or more reduction in...
Nonsteroidal Anti-Inflammatory Drug exposure associated with development of microscopic colitis
1. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) were independently associated with the development of microscopic colitis. Evidence Rating Level: 2 (Good) Microscopic...
![Maternal cell-free DNA sequencing superior to standard aneuploidy screening [CARE Study]](https://2minutemedicine-wpengine.netdna-ssl.com/wp-content/uploads/2014/02/47-karyotype-350x250.jpg)
Germline mutations in CIDEB confer protection from liver disease
1. Rare mutations in CIDEB are associated with a decreased risk of developing liver cirrhosis. 2. Further, rare mutations in...
Early peanut introduction was not associated with lower prevalence of peanut allergy
1. Introduction of a guideline recommending early peanut introduction to all infants was not associated with significant reduction in prevalence...
Nonoperative management of uncomplicated acute appendicitis comparable to appendectomy but leads to increased length of stay and disease recurrence
1. No significant differences in treatment success and rate of adverse events were detected in 8 randomized controlled trials of...
Tirzepatide reduces body weight and improves cardiometabolic function in patients with obesity
1. Tirzepatide treatment significantly reduced body weight and fat composition in obese patients while improving cardiometabolic risk factors and physical...
Multispecies probiotic reduces overall risk of diarrhea in antibiotic-treated children
1. In a small randomized controlled trial, administration of a multispecies probiotic during antibiotic therapy and for 7 days afterwards...
FOLFOX combined with nivolumab and trastuzumab in ERBB2-positive esophagogastric adenocarcinoma is an emerging therapy option
1. Overall survival rate at 12 months for the FOLFOX arm and ipilimumab arm was 70% and 57%, respectively. 2....
Treatment of anal high-grade squamous intraepithelial lesions can reduce rates of progression to invasive anal cancer.
1. The rate of progression was 57% lower in the group receiving anal HSIL treatment as compared to the group...
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