Transplantation followed by antiviral therapy cured hepatitis C in 100 percent of patients receiving...
1. All 20 patients included in the study were cured of HCV following antiviral therapy.
2. Similar eGFR scores were found between nontransplant and transplant...
Patisiran is effective in treatment of hereditary transthyretin amyloidosis.
1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 months of use.
2. Types...
More data needed to determine safety of probiotics and prebiotics
1. Studies are often lacking or inadequate with respect to reporting adverse events (AEs) related to probiotics and prebiotics.
2. The majority of the studies...
Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients...
1. Use of HCV-infected kidneys increased patients’ quality-adjusted life expectancy.
2. Lower costs were associated with HCV-infected kidneys compared to transplanting HCV-uninfected kidneys to HCV-positive...
Fruquintinib increases overall survival in metastatic colorectal carcinoma
1. In this phase 3 randomized controlled trial, fruquintinib increased median overall survival and progression-free survival compared to placebo in patients with colorectal cancer...
Patients with advanced adenomas are at increased risk of developing colorectal cancer
1. Patients with advanced adenomas identified on flex sigmoidoscopy had a significantly increased risk of death from colorectal cancer (CRC) compared to those with...
Improved research methods needed to determine effectiveness of anti-obesity public health initiatives
1. Researchers found that amongst nearly 300 studies reporting the impact of policies, programs, or changes in built environment on controlling and preventing obesity,...
Sigmoidoscopy reduces colon cancer risk for men, but not women
1. Sigmoidoscopy was associated with a reduction in the prevalence of colon cancer mortality in men.
2. Sigmoidoscopy did not appear to have a significant...
Optimizing organ donations from overdose deaths may help address national organ shortage
1. U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from organs donated by ODDs...
BEACON CRC Safety Lead-in Study suggests safety and efficacy of triplet combination therapy for...
1. BEACON CRC is a multicenter, randomized, phase 3 clinical trial evaluating the triplet combination of binimetinib (BINI, a MEK inhibitor) + encorafenib (ENCO,...
