Semaglutide associated with dose-dependent weight loss and resolution of nonalcoholic steatohepatitis
1. Nonalcoholic steatohepatitis (NASH) resolution without worsening of fibrosis occurred in a significantly greater percentage of patients who received semaglutide versus placebo, but the...
Comparison of life and healthy life expectancies between IBD patients and the general population
1. From 1996 to 2011, life expectancy for IBD patients increased by approximately 3 years, whereas from 1996 to 2008, healthy life expectancy decreased...
Efficacy and safety of short-term therapy with indigo naturalis for ulcerative colitis
1. Short-term indigo naturalis therapy demonstrated symptomatic improvement in patients with mild to moderate ulcerative colitis.
Evidence Rating Level: 1 (Excellent)
Treatment options for ulcerative colitis...
Lirentelimab may be effective for treatment of eosinophilic gastrointestinal disease
1. Patients who received AK002, lirentelimab, had far greater reductions in both gastrointestinal eosinophil burden and gastrointestinal symptoms compared to those who received placebo.
2....
IL-2 elevation after gluten exposure promising as a non-invasive diagnostic tool for Celiac Disease
1. In a small cohort of patients, IL-2 elevation after gluten challenge appears to be the earliest and most sensitive marker of gluten exposure...
Early introduction of gluten to infants associated with a lower incidence of celiac disease
1. The early introduction of the gluten into the diet of infants was associated with a lower incidence of celiac disease at age 3...
Sarcopenia associated with reduced muscle mass and strength following liver resection for malignant neoplasms
1. Sarcopenia was an independent risk factor for reduced muscle mass and strength following liver resection for malignant neoplasms.
Evidence Rating Level: 2 (Good)
Sarcopenia is...
Anemia associated with increased risk of developing Crohn’s disease, but not ulcerative colitis
1. Anemia increased the risk of development of Crohn’s disease, inversely to hemoglobin concentration
2. Anemia was not associated with an increased risk of ulcerative...
Conditional risk of diverticulitis after non-operative management
1. Among patients managed without surgery, the conditional recurrence-free survival of diverticulitis increased with each year survived recurrence-free.
2. Lower age and higher comorbidity burden...
Addition of bevacizumab to standard therapy improves outcomes in metastatic colorectal cancer
1. Adding bevacizumab to mFOLFOX6 therapy among patients with RAS mutant metastatic colorectal cancer led to an increased rate of liver metastases resection, which...
