Risk of major adverse cardiovascular events varies with dynamic metabolic syndrome status
1. In this retrospective study involving South Koreans with no history of major adverse cardiovascular events (MACE), persons who developed metabolic syndrome (MetS) within...
Combined Encorafenib-Binimetinib-Cetuximab therapy associated with longer overall survival in patients with BRAF V600E-mutated coloreactal...
1. A phase 3 randomized clinical trial showed that combined therapy using a BRAF inhibitor (encorafenib), EGFR monoclonal antibody (cetuximab) and a MEK inhibitor...
Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings...
1. After adjustment for established cardiovascular risk factors, the diagnosis of non-alcoholic fatty liver disease (NAFLD) does not appear to be associated with risk...
Development of Anti-Drug Antibodies to Infliximab (Remicade®) and Adalimumab (Humira®) in Patients With Crohn’s...
1. Carriage of the HLA-DQA1*05 allele is significantly associated with the development of antibodies against anti-TNF agents.Evidence Rating Level: 2 (Good)Anti-tumor necrosis factor (anti-TNF)...
Oxaliplatin-Based Adjuvant Chemotherapy for Rectal Cancer After Preoperative Chemoradiotherapy (ADORE): Long-Term Results of a...
1. Adjuvant FOLFOX improves disease-free survival in patients with pathologic Stage II or III rectal cancer after upfront surgery and preoperative chemoradiotherapy, but is...
Quick Take: Assessment of laparoscopic distal gastrectomy after neoadjuvant chemotherapy for locally advanced gastric...
1. Patients undergoing laparoscopic distal gastrectomy for locally advanced gastric cancer have better postoperative outcomes when compared to those undergoing traditional open distal gastrectomy.Evidence...
Dietary interventions have small effect on autism symptoms
1. A meta-analysis of studies evaluating dietary interventions used in treatment of autism spectrum disorder (ASD) in children found that omega-3, vitamin supplementation, and...
Diet trends over the past two decades in the United States
1. In this serial, cross sectional analysis over the last two decades, the adults in the United States decreased consumption of low-quality carbohydrates and...
Benefits of high-intensity surveillance following colorectal adenoma removal likely outweigh costs
1. In this microsimulation model of U.S. patients aged 50-79, high-intensity surveillance following colorectal adenoma provided clinically significant benefits over low-intensity surveillance at acceptable...
Daily aspirin may benefit some patients without existing cardiovascular disease
1. The benefit of daily aspirin varied dramatically depending on whether one cardiovascular disease event was equivalent to one or two bleeding events2. Subgroups...
