Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Quick Take: Effect of lorcaserin on prevention and remission of type 2 diabetes in...

There is a strong relationship between body weight and the risk of developing diabetes. Lorcaserin is a selective serotonin 2C receptor agonist that suppresses...

Lorcaserin does not increase rate of cardiovascular events in overweight or obese patients

1. At a median follow-up of 3.3 years, rates of composite cardiovascular events in at-risk overweight or obese patients treated with lorcaserin were not...

Tailoring fecal immunochemical tests positivity thresholds by age and sex may help to optimize...

1. Cancer detection among participants was higher with lower positivity thresholds. 2. Sensitivity with conventional fecal immunochemical tests (FIT) thresholds decreased with increasing age and...

Transplantation followed by antiviral therapy cured hepatitis C in 100 percent of patients receiving...

1. All 20 patients included in the study were cured of HCV following antiviral therapy. 2. Similar eGFR scores were found between nontransplant and transplant...

Patisiran is effective in treatment of hereditary transthyretin amyloidosis.

1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 months of use. 2. Types...

More data needed to determine safety of probiotics and prebiotics

1. Studies are often lacking or inadequate with respect to reporting adverse events (AEs) related to probiotics and prebiotics. 2. The majority of the studies...

Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients...

1. Use of HCV-infected kidneys increased patients’ quality-adjusted life expectancy. 2. Lower costs were associated with HCV-infected kidneys compared to transplanting HCV-uninfected kidneys to HCV-positive...

Fruquintinib increases overall survival in metastatic colorectal carcinoma

1. In this phase 3 randomized controlled trial, fruquintinib increased median overall survival and progression-free survival compared to placebo in patients with colorectal cancer...

Patients with advanced adenomas are at increased risk of developing colorectal cancer

1. Patients with advanced adenomas identified on flex sigmoidoscopy had a significantly increased risk of death from colorectal cancer (CRC) compared to those with...

Improved research methods needed to determine effectiveness of anti-obesity public health initiatives

1. Researchers found that amongst nearly 300 studies reporting the impact of policies, programs, or changes in built environment on controlling and preventing obesity,...
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