Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Electronic Cigarette and JUUL Use Among Adolescents and Young Adults

1. The use of electronic cigarettes is highly prevalent among adolescents and young adults through the advent of JUUL, which has unique implications for...

Adenotonsillectomy for obstructive sleep apnea in young children has no effect on cognition

1. Adenotonsillectomy done for obstructive sleep apnea (OSA) in children ages 3-5 years had no effect on cognition over time when compared to controls.2....

Osimertinib associated with longer overall survival versus comparator EGFR-TKIs

1. After a 3-year follow-up to a phase 3 trial, the epidermal growth factor receptor-tyrosine kinase inhibitor osimertinib resulted in a longer median overall...

Treatment Effect of Omalizumab on Severe Pediatric Atopic Dermatitis: The ADAPT Randomized Clinical Trial

1. In treatment-resistant childhood atopic dermatitis, omalizumab significantly reduced the severity of dermatitis and improved quality of life compared to placebo. Evidence Rating Level: 1...

Outcomes not improved with early amoxicillin-clavulanate in cardiac arrest patients

1. A 2-day course of amoxicillin-clavulanate and targeted temperature management of 32-34 degrees Celsius after cardiac arrest with shockable rhythm resulted in a lower...

M72/AS01E demonstrates sustained efficacy against pulmonary tuberculosis after 3 years

1. In this randomized trial involving HIV-negative African adults with latent tuberculosis, vaccination with M72/AS01E provoked an immune response and offered 50% protection against...

Clinical presentation, treatment, and short-term outcomes of lung injury associated with e-cigarettes or vaping

1.  Lung injury associated with e-cigarettes or vaping is a new disease entity that can be treated effectively with steroids; however, residual lung abnormalities...

Elexacaftor-tezacaftor-ivacaftor is efficacious in treating cystic fibrosis patients with Phe508del-minimal function genotypes

1. In this multicenter, phase 3 study of cystic fibrosis patients who were previously unresponsive to modulator regimens, triple-combination therapy with the next-generation corrector...

Lung cancer screening according to existing guidelines is likely cost-effective

1. In this study comparing three prominent lung cancer screening strategies, all were found to be cost-effective, yielding incremental cost-effectiveness ratios of under $100,000/quality...

Metoprolol not effective in preventing exacerbations of chronic obstructive pulmonary disease

1. In this double-blind randomized trial of COPD patients without previous indication for beta blocker therapy, treatment with extended-release beta-blockers failed to generate improved...
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