E-cigarette use may hamper smoking cessation for smokers planning to quit post-hospitalization
1. In a study of hospitalized smokers who planned to quit smoking post-discharge, users of e-cigarettes were not as likely as nonusers to refrain...
No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk...
1. Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma.
2....
Hemodynamic markers of pulmonary hypertension in heart failure with preserved ejection fraction are associated...
1. Pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF) is common in patients undergoing a right heart catheterization.
2. Transpulmonary gradient (TPG),...
Increased inhaled glucocorticoids do not prevent asthma exacerbations in children: The STICS trial
1. In children age 5 to 11 with mild-to-moderate persistent asthma treated with daily inhaled glucocorticoids, quintupling the dose of inhaled glucocorticoids during the...
Hydrocortisone plus fludrocortisone decreases mortality in adults with septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality...
Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The...
1. Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared to normal...
Adjunctive glucocorticoid therapy does not lower mortality in septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone infusion, did not have...
Vegetation size greater than 10 mm associated with increased risk of mortality in infective...
1. In this systematic review and meta-analysis, patients with infective endocardititis with vegetations greater than 10mm in size had significantly increased risk of systemic...
Prophylactic haloperidol not linked to improved survival in ICU patients: The REDUCE trial
1. In ICU patients, prophylactic haloperidol did not improve 28-day or 90-day survival.
2. Prophylactic haloperidol also did no reduce delirium incidence, delirium-free days, duration...
Aspirin comparable to rivaroxaban for extended venous thromboembolism prophylaxis following arthroplasty: The EPCAT II...
1. Patients initially treated with rivaroxaban following total knee or hip arthroplasty experienced similar rates of venous thromboembolism (VTE) regardless of continued rivaroxaban use...
