5-day versus 10-day course of remdesivir in patients with severe COVID-19
1. Compared to patients who received remdesivir for 10 days, those in the 5-day group experienced no significant difference in either clinical outcomes or...
Low COVID-19 infection rate among health care workers in Wuhan, China.
1. Front line health care workers in Wuhan had a lower rate of COVID-19 infection when compared to non-front line health care workers.
2. The...
Long-term use of rituximab associated with lower rates of AAV relapse
1. In this randomized controlled trial involving patients with antineutrophil cytoplasmic antibody-associated vasculitis in complete remission, administration of rituximab for an additional 18 months...
COVID-19 likely associated with high incidence of thromboembolic events
1. In this study of 12 decedents with COVID-19, deep venous thrombosis was observed in over half of the study population.
2. Pulmonary embolism was...
Antihypertensive medications and risk of COVID-19
1. Amongst the five examined classes of antihypertensive medications (ACE Inhibitors, ARBs, beta blockers, calcium-channel blockers, and thiazide diuretics), none were associated with a...
RT-PCR results during early SARS-CoV-2 infection course require cautious interpretation
1. The interpretation of reverse transcriptase polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was shown to require caution...
Remdesivir in adults with severe COVID-19
1. Adults with severe COVID-19 treated with remdesivir had numerically faster time to clinical improvement compared to controls, but the difference was not statistically...
Renin-angiotensin-aldosterone system inhibitors do not affect COVID-19 risk
1. Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) were not shown to affect the risk of COVID-19.
2. ACE inhibitors and ARBs were shown to...
Biomarkers obtained in the ED show limited utility in predicting pneumonia severity in children
1. In a study of children with community acquired pneumonia, initial biomarker levels (C-reactive protein, white blood cell count, procalcitonin, absolute neutrophil count) were...
Underlying cardiovascular disease associated with increased mortality in COVID-19 patients
1. Underlying cardiovascular disease was shown to be associated with increased risk of in-hospital death among coronavirus disease 2019 (Covid-19) hospitalized patients.
2. Angiotensin-converting-enzyme (ACE)...
