Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Lung cancer screening according to existing guidelines is likely cost-effective

1. In this study comparing three prominent lung cancer screening strategies, all were found to be cost-effective, yielding incremental cost-effectiveness ratios of under $100,000/quality...

Metoprolol not effective in preventing exacerbations of chronic obstructive pulmonary disease

1. In this double-blind randomized trial of COPD patients without previous indication for beta blocker therapy, treatment with extended-release beta-blockers failed to generate improved...

E-cigarette marketing associated with subsequent experimentation among youth

1. Youth and young adults who had never used tobacco were surveyed on exposure to electronic cigarette (e-cigarette) marketing and electronic nicotine delivery system...

Life-gained-based selection for cancer screening may result in superior health outcomes compared to risk-based...

1. In this modelling study, life-gained-based selection of smokers for lung cancer screening resulted in a nearly threefold greater gain in life expectancy per...

Vitamin C may not provide benefit in sepsis with acute respiratory failure

1. In this randomized clinical trial, intravenous infusion of high-dose vitamin C vs placebo for 96 hours resulted in no significant differences in the...

Lefamulin noninferior to moxifloxacin for community-acquired pneumonia

1. In this randomized controlled trial, oral lefamulin was noninferior to oral moxifloxacin for treating community-acquired pneumonia, with regards to early clinical response at...

Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for...

1. The use of nicotine e-cigarettes in addition to conventional nicotine patches may result in a modest improvement in smoking cessation when compared to...

The PAGE trial: clinical outcomes do not improve with inhaled GM-CSF in pulmonary alveolar...

1. In patients with pulmonary alveolar proteinosis, use of twice daily inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) did not improve clinical outcomes of vital capacity...

Quick Take: Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults...

Maintenance inhaled corticosteroid therapy is effective for preventing severe asthma exacerbations in patients with mild to moderate asthma at baseline. However, adherence to these...

Quick Take: Hospital volume and outcomes for acute pulmonary embolism

Patients with pulmonary embolism (PE) can present with a myriad of symptoms, and without prompt recognition and treatment, are at risk of developing life-threatening...
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