COVID-19 infection associated with increased risk of perioperative pulmonary and septic complications
1. COVID-19 infected patients were found to be at an increased risk of postoperative pulmonary and septic complications compared with a matched, non-infected cohort.
Evidence...
Use of inhaled corticosteroids is not associated with improved COVID-related mortality in patients with...
1. Patients with chronic obstructive pulmonary disease who were prescribed inhaled corticosteroids had an increased risk of COVID-19-related deaths compared to those on long-acting...
Diaphragm myopathy found in in critically ill patients with COVID-19
1. Patients with severe COVID-19 demonstrated a unique diaphragm myopathic phenotype compared to non-COVID-19 ICU patients.
2. It is unclear whether or not myopathy is...
Lessons from a Covid-19 outbreak on a naval aircraft carrier
1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was shown to spread rapidly amongst the U.S.S Theodore Roosevelt crew due to close close-quarter conditions...
Effectiveness of lorlatinib in advanced anaplastic lymphoma kinase-positive lung cancer
1. In this randomized, double-blind, phase three trial, progression-free survival was higher in patients treated with lorlatinib compared with crizotinib.
2. Lorlatinib treated patients had...
Post-extubation high-flow nasal cannula associated with higher rates of treatment failure in preterm infants
1. Rate of treatment failure within 7 days of extubation was higher in patients that received post-extubation high-flow nasal cannula (HFNC), as compared to...
Healthcare workers in patient facing roles at 3 times greater risk of COVID-19 hospital...
1. Healthcare workers in patient facing roles have a 3 times greater risk of being admitted for COVID-19, compared to the general population, and...
Discontinuing Nasal Continuous Positive Airway Pressure in infants ≤32 weeks gestational age
1. Among infants born ≤ 32 weeks gestational age requiring nasal continuous positive airway pressure (NCPAP), a gradual pressure wean to 3 cm H2O...
Lopinavir-ritonavir does not improve clinical outcomes in patients hospitalized with COVID-19
1. Compared to standard therapy, patients in the lopinavir-ritonavir treatment group did not show reductions in 28-day mortality and progression to invasive mechanical ventilation...
Genetic susceptibility for severe Covid-19 symptoms with respiratory failure
1. In Italian and Spanish populations, the chromosome locus 3p21.31 was identified with associated enrichment in coronavirus disease 2019 (Covid-19) patients with respiratory failure.
2....
