Study finds that pediatric residents rarely perform neonatal intubation
1. Advance practitioners and neonatal fellows had the highest rates of neonatal tracheal intubation (TI) attempts in the neonatal intensive care unit (NICU) and...
Lanadelumab may be an effective prophylactic treatment for hereditary angioedema
1. In this randomized controlled trial, prophylactic lanadelumab reduced attack frequency and severity in patients with hereditary angioedema compared to placebo.2. The most common...
Quick Take: Deep learning for chest radiograph diagnosis: A retrospective comparison of the CheXNeXt...
Deep learning approaches have been proposed as a way to facilitate the interpretation of chest radiographs in low resource settings. In this study, investigators...
Many new pediatric asthma cases attributable to obesity
1. One-tenth of new diagnoses of pediatric asthma could potentially be avoided with the elimination of childhood obesity.Evidence Rating Level: 2 (Good)Study Rundown: Despite...
Omalizumab (XOLAIR®) could be a new rescue option for asthma
1. In a case-report, 41-year-old patient requiring intubation for respiratory failure due to status asthmaticus clinically improved after administration of omalizumab (XOLAIR®).2. The findings...
Inhaled inorganic nitrites do not improve exercise capacity in heart failure with preserved ejection...
1. In this randomized controlled trial, there was no difference in mean peak oxygen consumption between patients with Heart Failure with preserved Ejection Fraction...
Sildenafil (Viagra) does not improve quality of life for idiopathic pulmonary fibrosis patients treated...
1. In patients with idiopathic pulmonary fibrosis (IPF) and a low diffusion capacity for carbon dioxide (DLCO), the addition of sildenafil to a treatment...
Triple combination regimen appears safe and effective for cystic fibrosis
1. Treatment with the cystic fibrosis transmembrane conductance regulator (CFTR) protein corrector VX-659 in combination with tezacaftor–ivacaftor significantly improved measures of lung function and...
Algorithm safely rules out pulmonary embolism in pregnant women
1. A diagnostic model based on D-dimer measurement, lower limb compression ultrasonography (CUS) and computed tomography pulmonary angiography (CTPA) accurately ruled out pulmonary embolism...
Continuous or extended combined oral contraceptive regimens not linked to higher venous thromboembolism risk
1. In this retrospective cohort study, continuous (84/7) or extended (365/0) cycle regimens of combined oral contraceptives were not linked with meaningfully higher rates...
