Lower and higher oxygen saturation targets result in equal but contrasting outcomes for extremely...
1. In this meta-analysis, there was no significant difference between lower and higher oxygen saturation targets on a primary composite of mortality or major...
Recombinant human pentraxin 2 slows the decline in lung function for patients with idiopathic...
1. The use of recombinant human pentraxin 2 vs placebo resulted in a slower decline in lung function over 28 weeks for patients with...
Viruses not linked to asthma exacerbation severity
1. Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.
Evidence Rating Level: 2 (Good)
Study Rundown: Viral...
ECMO for severe ARDS does not improve mortality
1. Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) did not show a 60-day mortality benefit compared to conventional ventilation and...
Budesonide-formoterol as needed superior to terbutaline in mild asthma: The SYGMA trial
1. In patients with mild asthma, use of the inhaled combined corticosteroid (ICS) and beta agonist budesonide-formoterol as needed was superior to terbutaline as...
Decrease in medication use among US children and adolescents
1. While overall prescribing of medications decreased compared to the early 2000s, the use of ADHD medication, asthma medicine, and contraceptive use increased while...
Vasopressin plus catecholamines lowers risk of atrial fibrillation in distributive shock
1. In this meta-analysis, addition of vasopressin to catecholamine vasopressors was associated with a lower risk of atrial fibrillation when compared to catecholamine monotherapy.
2....
Atropine plus propofol similar to atropine plus atracurium and sufentanil for non-emergent intubation in...
1. In this randomized controlled trial, the frequency of prolonged desaturation during neonatal, nonemergent intubation was similar between atropine plus propofol compared to atropine...
E-cigarette use may hamper smoking cessation for smokers planning to quit post-hospitalization
1. In a study of hospitalized smokers who planned to quit smoking post-discharge, users of e-cigarettes were not as likely as nonusers to refrain...
No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk...
1. Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma.
2....
