Neurology

Reports of high-impact neurology studies by medical professionals

Contribution of dementia to US mortality rates drastically underestimated in standard mortality statistics

1. Causes of death reported on death certificates drastically underestimated dementia mortality burden by a factor of 2.7. 2. Non-Hispanic Black persons demonstrated significantly greater...

New post-stroke management program significantly reduces cardiovascular events and improves quality of life

1. Cardiovascular events were significantly lower with a novel post-stroke management program compared to current standard care. 2. Post-stroke patients reported significantly better health-related quality...

Ofatumumab may reduce annual relapse rates compared to teriflunomide in multiple sclerosis

1. In this double-blind, randomized phase 3 trial, patient treated with ofatumumab had a lower annualized relapse rate in multiple sclerosis compared to those...

Further evidence that Zika virus disease associated with brain and eye birth defects

1. The prevalence of brain and eye defects was elevated during the 2015-2016 Zika virus outbreak in Colombia compared to the periods immediately before...

Trends in antihypertensive medication use among individuals with a history of stroke and hypertension

1. In a large, national sample, approximately 37.1% of patients with stroke history had uncontrolled blood pressure. 2. Most patients on medication were taking angiotensin-converting...

Metformin associated with retention of cognitive ability and reduced white matter loss in pediatric...

1. Metformin was found to be safe and tolerable in survivors of pediatric brain tumors. 2. Metformin was associated with retention of memory and processing...

Association of delirium with long-term cognitive decline

1. Delirium was significantly associated with long-term cognitive decline. 2. Across all studies, delirium groups demonstrated worse cognitive outcomes than control groups. Evidence Rating Level: 2...

Intracranial atherosclerosis on 7T MRI and cognitive functioning – the SMART-MR study

1. Among patients with vascular disease, high burden of atherosclerotic lesions in the posterior circulation as well as the posterior cerebral artery was associated...

Ticagrelor and aspirin taken post stroke may decrease the risk of recurrent stroke

1. Ticagrelor and aspirin taken after a mild-to-moderate acute non-cardioembolic stroke or high-risk transient ischemic attack led to a lower rate of subsequent stroke...

Association of rapid eye movement sleep with mortality in middle-aged and older adults

1. Decreasing amounts of REM sleep was associated with an increased risk of all-cause mortality. 2. The most profound risk was seen among individuals experiencing...
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