Neurology

Reports of high-impact neurology studies by medical professionals

Prescription of Benzodiazepines, Z-Drugs, and Gabapentinoids and Mortality Risk in People Receiving Opioid Agonist...

1. Co-prescription of benzodiazepines and z-drugs with opioid agonists was associated with a significantly increased risk of drug-related poisoning in opioid-dependent individuals.Evidence Rating Level:...

Growth Faltering is Associated With Altered Brain Functional Connectivity and Cognitive Outcomes In Urban...

1. Height-for-age z-score was negatively associated with brain functional connectivity (FC), with FC serving as a mediating factor between child growth and future intellectual...

Efficacy and Safety of Lanabecestat for Treatment of Early and Mild Alzheimer Disease

1. While well-tolerated in early and mild Alzheimer’s disease, the BACE1 inhibitor lanabecestat was generally ineffective in slowing cognitive and functional decline.Evidence Rating Level:...

Lower LDL cholesterol level after ischemic stroke decreases risk of subsequent stroke

1. This randomized controlled trial showed that patients with ischemic stroke or transient ischemic attack with target LDL levels of less than 70 mg/dL...

Association of Sex With Outcomes in Patients Undergoing Percutaneous Coronary Intervention

Bleeding after percutaneous coronary intervention (PCI) was more common in women, but the effect of two antiplatelet strategies on death and new Q-wave...

Mortality from neurodegenerative disease may be higher among former professional soccer players

1. In this retrospective cohort study, mortality from neurodegenerative disease was higher among former professional soccer players than the control group. Mortality related to...

Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease

Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease1. Widespread cholinergic deficits found in early-onset Alzheimer’s disease (AD) may...

Effect of Continued Folic Acid Supplementation Beyond the First Trimester of Pregnancy on Cognitive...

1. Folic acid supplementation prevents neural tube deficits during pregnancy, but if continued beyond the recommended first trimester, may positively impact neurodevelopment and cognitive...

Hospital elder life program linked to improved function, lower risk of delirium in post-operative...

1. In this randomized clinical trial in China of a tailored, family-involved hospital elder life program (t-HELP) was linked to a substantially lower risk...

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings...

1. After adjustment for established cardiovascular risk factors, the diagnosis of non-alcoholic fatty liver disease (NAFLD) does not appear to be associated with risk...
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