Neurology

Reports of high-impact neurology studies by medical professionals

Cluster analysis identifies phenotype groups for atrial fibrillation with unique clinical outcomes

1. Cluster analysis of a population of patients with atrial fibrillation (AF) identified four unique phenotypes using variables not traditionally associated with AF classification. 2....

Dabigatran shown to be a safe and effective alternative to warfarin for reducing stroke...

1. The analysis of data from more than 50,000 patients showed that both dabigatran and warfarin were associated with similar amounts of bleeding and...

Cohort study suggests that functional impairment and decline are common in middle age

1. Functional impairment in activities of daily living (ADLs) and/or instrumental ADL (IADL), functional decline, and shifts between independence and functional impairment are all...

ACE-inhibitors and statins do not impact albuminuria in adolescents with type 1 diabetes mellitus:...

1. In adolescents with type 1 diabetes mellitus, the albumin-to-creatinine ratio was not significantly changed by angiotensin-converting-enzyme (ACE) inhibitors alone, statins alone, or the...

Despite improving trends in lupus-related mortality, rates appear to remain high relative to non-lupus...

1. Over the 46-year study period, systemic lupus erythematosus (SLE) age-standardized mortality rates (ASMRs) did not decline as much as non-SLE ASMR, and there...

Stroke associated with increasing disability trajectory as compared to myocardial infarction

1. In this population-based prospective cohort study, the trajectory of increasing disability was significantly steeper after stroke than after myocardial infarction. 2. Further study to...

Only a small fraction of diabetes cases go undiagnosed

1. Undiagnosed diabetes was more common in overweight or obese adults, older adults, racial and ethnic minorities, and patients lacking health insurance. 2. The majority...

Low-dose alteplase did not show differential benefits across age, ethnicity or severity of stroke...

1. In this secondary analysis of the Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED), there were no significant difference in treatment effects...

Supplemental oxygen does not reduce mortality in stroke patients

1. This randomized clinical trial showed that among patients with acute stroke, supplementary low-dose oxygen for 72 hours (either nocturnal or continuous) did not...

Chronic auditory toxicity linked to peak unbound bilirubin levels

1. Unbound bilirubin (UB) was significantly associated with neonatal chronic auditory toxicity. 2. Total serum bilirubin (TSB) and bilirubin albumin molar ratio (BAMR) were...
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