Neurology

Reports of high-impact neurology studies by medical professionals

Ezogabine with potential to slow disease progression for amyotrophic lateral sclerosis in phase 2...

1. Dose-dependent ezogabine was shown to decrease motor neuron excitability, a marker of disease progression, in patients with amyotrophic lateral sclerosis. Evidence Level Rating: 1...

Death of a partner associated with subsequent increase in ischemic stroke and intracerebral hemorrhage

1. Partner death was associated with both ischemic stroke and intracerebral hemorrhage in the subsequent five years, though absolute risk differences were small. 2. Risk...

Microbleeds associated with increased risk of stroke

1. Microbleeds increase risk of intracerebral hemorrhage, ischemic stroke, recurrent stroke, and mortality. 2. Microbleeds do not appear to influence the effects of rivaroxaban treatment. Evidence...

Incidence trends of optic neuritis and its association with immune-mediated inflammatory diseases

1. Incidence of optic neuritis remained stable in the UK across 22 years. 2. Participants with optic neuritis demonstrated significantly greater odds of several immune-mediated...

Low dose edoxaban prevents stroke in elderly patients with atrial fibrillation

1. Low dose edoxaban was superior to placebo in preventing stroke or systemic embolism for very elderly patients with nonvalvular atrial fibrillation at risk...

Sodium phenylbutyrate-taurursodial in amyotrophic lateral sclerosis patients

1. Sodium phenylbutyrate-taurursodial slowed the functional decline in patients with amyotrophic lateral sclerosis. 2. The mean rate of change for slow vital capacity and plasma...

Identification of modifiable social and behavioral factors associated with childhood cognitive performance

1. Moderate increases in positive exposures were associated with improved cognitive performance in children. 2. Black children experienced fewer cognitively beneficial exposures than other racial...

Low-Field, portable MRI a feasible neuroimaging alternative to traditional MRI for ICU patients

1. Low-field, portable MRI appears to be a feasible neuroimaging option for patients hospitalized in ICUs and unable to be transported for traditional MRI. 2....

Contribution of dementia to US mortality rates drastically underestimated in standard mortality statistics

1. Causes of death reported on death certificates drastically underestimated dementia mortality burden by a factor of 2.7. 2. Non-Hispanic Black persons demonstrated significantly greater...

New post-stroke management program significantly reduces cardiovascular events and improves quality of life

1. Cardiovascular events were significantly lower with a novel post-stroke management program compared to current standard care. 2. Post-stroke patients reported significantly better health-related quality...
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