Neurology

Reports of high-impact neurology studies by medical professionals

Quick Take: The burden of health conditions for middle-aged and older adults in the...

Understanding the burden of health conditions in older adults in the U.S. is essential in addressing the healthcare demands of this patient population. This...

Verubecestat linked to worse outcomes among patients with prodromal Alzheimer’s Disease compared to placebo

1. Verubecestat, an orally administered beta amyloid precursor protein-cleaving enzyme 1 (BACE-1) inhibitor , did not slow or prevent the progression of dementia among patients...

Poor scam awareness may be associated with increased risk of dementia

1. In this prospective cohort study on aging, poor scam awareness measured by questionnaire was associated with an increased risk of Alzheimer’s Dementia (AD),...

Rivaroxaban likely reduces risk of recurrent stroke in specific subgroup of patients with embolic...

1. In this post-hoc analysis of data from the NAVIGATE-ESUS trial, which evaluated strategies to prevent recurrent stroke in patient of embolic stroke of...

Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the...

Intravenous thrombolytic therapy with alteplase (recombinant human tissue plasminogen activator) is approved for the treatment of acute ischemic stroke. However, whether it is efficacious...

In phase 3 trial, rituximab not associated with clinical improvement in patients with Myalgic...

1. In this randomized controlled trial, B-lymphocyte depletion through rituximab did not significantly improve fatigue symptoms of patients with ME/CFS compared to the placebo...

Amyloid-PET imaging leads to changes in management in patients with dementia

1. In this prospective cohort study, changes in clinical management occurred after amyloid-PET imaging for a majority of patients with mild cognitive impairment (MCI)...

Quick Take: Epidemiology of brain death in pediatric intensive care units in the United...

In the United States, brain death is exclusively diagnosed in critical care settings, owing to the need for mechanical ventilatory support. With ongoing controversy...

Quick Take: The contribution of cannabis use to variation in the incidence of psychotic...

Previous observational studies have supported a causal link between cannabis use and psychotic disorder. A recent meta-analysis has also shown a dose-response association with...

Quick Take: Rates of extreme neonatal hyperbilirubinemia and kernicterus in children and adherence to...

Neonatal hyperbilirubinemia, left untreated, may lead to lifelong neurodevelopmental impairment. Fortunately, effective tools in risk assessment, prevention, diagnosis and treatment exist, making this a...
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