Neurology

Reports of high-impact neurology studies by medical professionals

Thrombectomy improves functional outcomes for imaging screened patients 6 to 16 hours after stroke:...

1. Patients presenting with ischemic stroke 6 to 16 hours after they were last known to be well had improved functional outcomes at 90...

Nusinersen improves motor function in children with later-onset spinal muscular atrophy: The CHERISH trial

1. Intrathecal injections of nusinersen in pediatric later-onset spinal muscular atrophy (SMA) patients were associated with increased clinical motor function scores compared to sham...

Influenza vaccine not associated with increased risk of epilepsy in children

1. No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway. Evidence Rating Level:...

Quality of care for transient ischemic attack and minor stroke vary across country

1. In this study about quality of care for patients with TIA or minor stroke, there was substantial variation in adherence to guidelines for...

Mogamulizumab is safe and possibly effective in HTLV-1-associated myelopathy

1. In this combined phase 1-2a study, mogamulizumab used for treatment of human T-lymphotropic virus type 1 (HTLV-1) associated myelopathy was safe and associated...

Fetal alcohol spectrum disorders likely to be vastly underdiagnosed in US

1. A multisite, cross-sectional study found a large mismatch between previously diagnosed fetal alcohol spectrum disorders and the actual prevalence of cases identified. Evidence Rating...

Preoperatively diagnosed patent foramen ovale linked to increased perioperative stroke risk

1. A preoperatively diagnosed patent foramen ovale was associated with an increased risk of stroke within 30 days of non-cardiac surgery. Evidence Rating Level: 2...

Acute lymphoblastic leukemia disease burden associated with safety and efficacy of CD19-CAR therapy

1. Patients with a higher disease burden of acute lymphoblastic leukemia (ALL) treated with CD19-specific chimeric antigen receptor (CAR) T cell therapy experienced greater...

Living kidney donation associated with some increased health risks

1. Living kidney donation was associated with higher diastolic blood pressure, lower estimated glomerular filtration rates, and increased relative risk of preeclampsia and end-stage...

Solanezumab does not change cognitive decline in mild Alzheimer’s disease

1. In patients with mild Alzheimer’s disease solanezumab, an antibody designed to facilitate clearance of amyloid-beta plaques, did not significantly reduce cognitive decline over...
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