Neurology

Reports of high-impact neurology studies by medical professionals

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings...

1. After adjustment for established cardiovascular risk factors, the diagnosis of non-alcoholic fatty liver disease (NAFLD) does not appear to be associated with risk...

Quick Take: Effect of Collaborative Dementia Care via Telephone and Internet on Quality of...

1. A model of dementia care management implemented through telephone and internet was shown to be more effective in improving health outcomes in patients...

Quick Take: Using Acute Optic Neuritis Trials to Assess Neuroprotective and Remyelinating Therapies in...

1. Acute optic neuritis appears may be an appropriate condition to test neuroprotective and re-myelinating therapies after acute inflammation in multiple sclerosis.Evidence Rating Level:...

Mixed outcomes from surgical evacuation of cerebellar intracerebral hemorrhage

1. In this meta-analysis, the proportion of patients with cerebellar intracerebral hemorrhage who underwent surgical evacuation and had a favorable functional outcome was not...

Dietary interventions have small effect on autism symptoms

1. A meta-analysis of studies evaluating dietary interventions used in treatment of autism spectrum disorder (ASD) in children found that omega-3, vitamin supplementation, and...

Quick Take: The clinical effectiveness of sertraline in primary care and the role of...

1. Selective serotonin reuptake inhibitors (SSRIs) are not associated with significant short-term reductions in depressive symptoms in the primary care setting, but reduce short-term...

Quick Take: Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine

1. Donepezil is associated with an elevated short-term risk of hospital admission for rhabdomyolysis compared to rivastigmine or galantamine for Alzheimer’s disease and dementia.Evidence...

Quick Take: Efficacy and Long-term Peripheral Sensory Neuropathy of 3 vs 6 Months of...

1. A shortened course of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer was associated with decreased peripheral sensory neuropathy without compromising effectiveness.Evidence Rating...

Quick Take: Serum neurofilament light chain levels in patients with presymptomatic multiple sclerosis

1. Increased serum neurofilament light chain levels, a biomarker for neuroaxonal damage, may be associated with a prodromal or subclinical phase in the setting...

SAGE-217 reduces depressive symptoms in patients with major depression within 2 weeks

1. Patients with major depression randomized to receive SAGE-217, a positive allosteric modulator of γ-aminobutyric acid (GABA) type A receptors, experienced fewer depressive symptoms...
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