Replacement of recipient hematopoietic cells with donor cells may be a major factor in...
1. Allo-HSCT treatment resulted in significant prolonged reduction in HIV-1 viral reservoirs.
2. Mouse models showed adoptive transfer of peripheral CD4+ T cells to immunosuppressed...
ICU admissions among Medicare beneficiaries on a decade-long downward trend
1. Intensive care unit (ICU) admission rates decreased from 2006 to 2015.
2. No association was found between percentage change in ICU beds and admissions...
Early and delayed renal-replacement therapy for septic shock associated acute kidney injury show similar...
1. Among patients with septic shock and acute kidney injury (AKI), there was no significant difference in 90-day mortality between early (within 12 hours)...
Quick Take: Effect of Immediate vs Delayed Pushing on Rates of Spontaneous Vaginal Delivery...
Although more than 3 million women give birth in the United States each year, there is no consensus regarding the optimal timing of maternal...
Use of non-steroidal anti-inflammatory drugs (NSAIDs) for musculoskeletal pain not linked with adverse outcomes...
1. In this retrospective cohort analysis, patients with a history of hypertension, chronic kidney disease, or heart failure presenting to primary care physicians for...
Quick Take: Single-dose versus 7-day-dose metronidazole (Flagyl) for the treatment of trichomoniasis in women:...
Trichomoniasis is the most common sexually transmitted infection among women worldwide. Untreated, this can lead to poor reproductive outcomes and increased rates of HIV...
Quick Take: Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor...
Glucagon-like peptide-1 (GLP-1) potentiates the release of insulin from pancreatic beta cells in a glucose-dependent manner. While pharmacologic studies have shown that GLP-1 delays...
Quick Take: Effect of lorcaserin on prevention and remission of type 2 diabetes in...
There is a strong relationship between body weight and the risk of developing diabetes. Lorcaserin is a selective serotonin 2C receptor agonist that suppresses...
Recurrence of Group B Streptococcal infection similar in shortened and prolonged therapy
The rates of Group B Streptococcal (GBS) bacteremia recurrence in infants with an initial course of late-onset infection who received shortened and prolonged IV...
Polymyxin B hemoperfusion unlikely to reduce mortality for sepsis
1. In this randomized controlled trial, hemoperfusion with polymyxin B resulted in similar 28-day mortality compared to sham hemoperfusion for patients with sepsis with...
