The Evolut Low Risk Trial: Self-expanding TAVR noninferior to surgery in low-risk patients

1. Among patients with severe aortic stenosis at low-risk for surgery, transcatheter aortic valve replacement (TAVR) with a self-expanding valve was noninferior to surgical...

The PARTNER 3 Trial: TAVR with balloon-expandable valves has favorable post-surgical outcomes among low-risk...

1. This randomized control trial compared post-surgical outcomes between transcatheter aortic-valve replacement (TAVR) with balloon-expandable valves or surgical valve replacement in low- risk surgical...

Platelet transfusions at higher threshold associated with greater risk of death in preterm infants

1. Preterm infants given prophylactic platelet transfusions at thresholds below 50,000 platelets per cubic millimeter had higher risks of death or major bleeding after...

Melanoma as a possible cause of autoimmune encephalitis

1. A woman developed anti-AMPA receptor encephalitis in the setting of metastatic melanoma.2. Following a short delay, she responded well to vemurafenib and cobimetinib....

Psychiatric emergency visits increasing among youth, especially racial minorities

1. An analysis of emergency department (ED) visits across the United States showed a 28% overall increase in psychiatric ED visits per 1000 youth...

Direct oral anticoagulants for atrial fibrillation in patients with mitral stenosis

1. In this retrospective observational study, direct oral anticoagulant use for atrial fibrillation in patients with mitral stenosis was linked with decreased mortality and...

Quick Take: Veverimer versus placebo in patients with metabolic acidosis associated with chronic kidney...

Chronic metabolic acidosis is often seen in patients with chronic kidney disease (CKD), and results from an inability to excrete metabolically produced acid. This,...

Quick Take: Association of Atopic Dermatitis With Sleep Quality in Children

Atopic dermatitis, a common disorder in the pediatric population, is associated with pruritus that is often worse at night and, thus, can interfere with...

Quick Take: Chlorhexidine Versus Routine Bathing to Prevent Multidrug-Resistant Organisms and All-Cause Bloodstream Infections...

Universal decontamination in the intensive care unit (ICU) has led to success in reducing bloodstream infections and infections with multi-drug resistant organisms. In this...

Tramadol may be associated with increased mortality among patients with osteoarthritis

1. In this retrospective cohort of patients with osteoarthritis, tramadol had a significantly higher risk of mortality over 1 year compared to NSAIDs, though...
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