Rifapentine-moxifloxacin noninferior to standard of care treatment for pulmonary tuberculosis

1. Rifapentine-moxifloxacin treatment was shown to be non-inferior compared to standard therapy for tuberculosis. 2. Rifapentine without moxifloxacin treatment was shown to be inferior to...

Upadacitinib non-inferior to adalimumab for psoriatic arthritis treatment

1. Janus kinase (JAK) inhibitor upadacitinib showed non-inferior efficacy in improving psoriatic arthritis compared to standard-of-care adalimumab. 2. High-dose upadacitinib was associated with more frequent...

Lumasiran decreases urinary oxalate excretion in Primary Hyperoxaluria Type 1

1. Lumasiran was shown to decrease urinary oxalate excretion in patients with Primary Hyperoxaluria Type 1. 2. Lumasiran was shown not to cause severe or...

Special Report: Psychedelics in Medicine Part 1: Psychedelics as a potential therapeutic option for...

Section 1: Psychedelics as a potential therapeutic option for psychiatric conditions Psychedelic drugs, such as lysergic acid diethylamide (LSD), was of interest to molecular psychiatry...

Vulnerability of Never-Smoking Youth to Cigarette Smoking and Tobacco Industry Marketing

1. In a large and diverse cohort study, multiple susceptibility factors accurately predicted smoking outcomes 4 years later.  2. Exposure to tobacco marketing and electronic...

Discontinuation of oxytocin during active labour may reduce fetal heart rate abnormalities

1. In women undergoing active labour, discontinuation of oxytocin was associated with a slightly higher risk of caesarean section compared to continued oxytocin use. 2....

Infectivity of SARS-CoV-2 in children compared with adults

1. Children are most likely not the dominant drivers of COVID-19 transmissions, as their COVID test specimens were not as likely to grow in...

Diagnosis of atopic dermatitis in children may be associated with lower educational attainment

1. Individuals diagnosed with atopic dermatitis (AD) as children were at elevated risk of not attaining lower and upper secondary education, compared to the...

No difference in live birth rates between intracytoplasmic sperm injection and conventional in-vitro fertilization...

1. For couples with a male partner with normal sperm counts and motility, intracytoplasmic sperm injection did not result in higher rates of live...

Substance use among hospitalized adolescents infrequently documented in electronic health record

1. In a cross-sectional study of hospitalized adolescents, approximately one third reported ever using alcohol, marijuana, electronic cigarettes, or a combination of ≥2 substances. 2....

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