Very-low-calorie diet leads to significant but reversible changes in gut microbiome

1. Very-low-calorie diet significantly altered composition of the gut microbiome in study participants, including an enrichment in pathogenic Clostridiodies difficile. 2. Stool samples from post-diet...

Longer seated lunch time associated with more consumption of fruit and vegetables in children

1. Compared to 10-minuted seated lunch, 20-minuted seated lunch led to increased amount of fruit and vegetables consumed amongst children. 2. 20-minute lunch did...

Impact of frailty on clinical outcomes and resource use following emergency general surgery in...

1. Following emergency general surgery procedures, frail patients had poorer clinical outcomes such as higher mortality, non-home discharge rates, and hospital readmissions, as well...

Home health management of patients undergoing deep brain stimulation for Parkinson’s disease is safe...

1. Among patients receiving deep brain stimulation for Parkinson’s disease, a home health management program was found to be safe, feasible, and significantly reduced...

Computed tomography findings may be useful in prognostication for mild traumatic brain injury

1. Computed tomography (CT) findings improved generalized estimating equation models predicting whether a patient would experience incomplete recovery or unfavorable outcome in mild traumatic...

Adjuvant celecoxib not associated with improved disease-free survival in patients with ERBB2-negative breast cancer

1. The study found no evidence of benefit to disease-free survival when 400 mg of celecoxib was administered once daily for 2 years in...

Automated behavioral intervention for improving workplace diet did not prevent weight gain

1. Work-place behavioral interventions for improving diet choices and weight management can be automated and personalized based on cafeteria purchase history. 2. Personalized, automated behavioral...

Ipatasertib plus abiraterone significantly improves survival in patients with PTEN-negative prostate cancer compared to...

1. Ipatasertib-abiraterone treatment significantly improved progression-free survival compared to placebo-abiraterone in patients with PTEN-loss metastatic castration-resistant prostate cancer. 2. Grade 3 or greater adverse events...

Canakinumab not associated with increased survival without invasive mechanical ventilation among patients hospitalized with...

1. Among patients hospitalized with severe COVID-19 and hyperinflammation, treatment using the anti-interleukin-1β antibody canakinumab, compared with placebo, did not significantly increase the likelihood...

Predicting mortality among septic patients presenting to the emergency department–a cross sectional analysis using...

1. In a large cohort from Sweden, six variables focused on symptoms, observations, and mode of arrival to the hospital, were found to be...

All-time hits