Dexamethasone decreased mortality in hospitalized COVID-19 patients

1. Patients hospitalized with COVID-19 and treated with dexamethasone showed an overall decrease in 28-day mortality compared to those treated with usual care. 2. Dexamethasone...

ACEi and ARB use not associated with increased risk of COVID-19 hospitalization or mortality

1. There is no association between ACE inhibitor or ARB use compared with other antihypertensives for risk of COVID-19 hospitalization for outpatients. 2. There...

COVID-19 lockdowns associated with increased quiet time and less spoken communication for children with...

1. During the COVID-19 pandemic lockdowns, schoolchildren with cochlear implants were exposed to more quiet time and less spoken communication, with a speech:quiet ratio...

Relugolix combination therapy led to reduction in uterine fibroid symptoms

1. Once-daily relugolix combination therapy resulted in a significant reduction in heavy menstrual bleeding compared with placebo in women with uterine fibroids. 2. The combination...

Xanomeline-trospium treatment showed improvement in patients with schizophrenia

1. Xanomeline-trospium treatment showed a greater reduction in the degree of psychosis in patients with schizophrenia compared to placebo. 2. Patients treated with xanomeline-trospium experienced...

Idecabtagene vicleucel showed a response in pre-treated multiple myeloma

1. Idecabtagene vicleucel treatment showed substantial antitumor activity in the majority of pre-treated patients with refractory and relapsed myeloma. 2. Almost all patients had grade...

Transdermal estrogen shows similar cardiovascular safety profile to traditional luteinizing hormone therapy in patients...

1. The use of long-term transdermal estrogen for castration therapy for prostate cancer showed no difference in cardiovascular events versus current standard of care. 2....

Higher SARS-CoV-2 infection rate in pregnant patients

1. In Washington State, pregnant patients were found to be at a higher risk of SARS-CoV-2 infection. 2. Results were more pronounced if patients belonged...

Cemiplimab monotherapy significantly improves outcomes in patients with advanced non-small-cell lung cancer with PD-L1...

1. Median overall survival and progression-free survival were significantly improved with cemiplimab monotherapy compared to chemotherapy. 2. Patients treated with cemiplimab monotherapy reported fewer grade...

Pulmonary arterial pruning and longitudinal change in percent emphysema and lung function

1. Among patients with and without COPD, a greater magnitude of pulmonary arterial pruning as measured by CT imaging was associated with a faster...

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