Variable homicide mortality rates among women aged 15-44 years depending on state abortion policy
1. National homicide mortality rates among United States women aged 15-44 years increased during the COVID-19 pandemic and decreased starting...
Children with intellectual and developmental disabilities have increased risks of depression and anxiety
1. Children who had an intellectual and developmental disabilities (IDD) had significantly higher risks of depression and anxiety compared with...
2MM: Longevity Roundup – Sleep patterns track with biological aging, earlier menopause signals cognitive decline, diet predicts aging-related mortality, and lifestyle intervention preserves mobility in frailty
Sleep quality and regularity track with biological aging across multiple systems Sleep duration alone may be an incomplete way to...
Brepocitinib becomes first oral therapy approved for adult dermatomyositis
1. Brepocitinib is the first oral therapy specifically approved for adults with dermatomyositis, providing a disease-specific alternative to treatment strategies...
Daraxonrasib extends survival in metastatic pancreatic cancer
1. Daraxonrasib is the first-in-class RAS inhibitor approved for metastatic pancreatic adenocarcinoma, addressing a molecular pathway that drives most pancreatic...
Ecopipam reduces relapse risk in pediatric Tourette syndrome
1. Ecopipam is a first-in-class investigational selective dopamine D1 receptor antagonist under priority review for pediatric Tourette syndrome, offering a...
First messenger RNA influenza vaccine outperforms standard-dose vaccination
1. mFlusiva is the first messenger RNA influenza vaccine approved in the United States, with the FLUENT phase 3 trial...
2MM: Pharma Roundup – mRNA flu vaccine debuts, RAS inhibition extends pancreatic cancer survival, and new therapies advance for dermatomyositis and Tourette syndrome
mFlusiva outperforms standard-dose flu vaccine in adults 50 and older The U.S. Food and Drug Administration (FDA) approved mFlusiva (mRNA-1010)...
Real-time AI guidance enters live brain tumor surgery
1.University College London (UCL) and University College London Hospitals (UCLH) have performed the first surgery in an ongoing clinical trial...
FDA-cleared AI devices rarely have patient outcome data
1. Among 1,357 FDA-authorized artificial intelligence and machine learning-enabled medical devices, only 34 were linked to registered prospective trials and...
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