BEACON CRC Safety Lead-in Study suggests safety and efficacy of triplet combination therapy for...
1. BEACON CRC is a multicenter, randomized, phase 3 clinical trial evaluating the triplet combination of binimetinib (BINI, a MEK inhibitor) + encorafenib (ENCO,...
Nivolumab plus ipilimumab improve survival in advanced renal cell carcinoma
1. Amongst patients with advanced renal-cell carcinoma and an intermediate or poor prognosis, nivolumab plus ipilimumab was superior to sunitinib alone in improving overall...
Venetoclax plus rituximab increases progression-free survival in relapsed chronic lymphocytic leukemia
1. Patients with relapsed or remitting chronic lymphocytic leukemia (CLL) treated with venetoclax-rituximab had a greater 2-year progression-free survival rate compared to bendamustine-rituximab treated patients.
2....
Accountable Care Organizations linked to modest increase in appropriate cancer screening
1. Enrollment in Medicare Shared Savings Program (MSSP) Accountable Care Organizations (ACO) was associated with a decrease in breast cancer screening, increase in colorectal...
USPSTF: Behavioral interventions do not reduce sunburn or skin cancer outcomes in adults
1. Behavioral interventions increase sun protection behavior but do not reduce sunburn or skin cancer outcomes in adults.
2. Behavior interventions lead to increased skin...
Colonoscopy significantly reduces mortality from colorectal cancer in Veterans Affairs study
1. Colonoscopy in veterans was associated with reduced mortality from both left and right-sided colorectal cancer.
2. Mortality was reduced by 61% in patients screened...
iPad app that allows patients to order tests doubles colon cancer screening rates in...
1. Digital health intervention resulted in significantly higher colon cancer screening rates among participants.
2. No statistically significant relationship was observed between the digital health...
Single PSA screening increases prostate cancer detection but does not change mortality
1. In this randomized controlled trial, men who were screened with a single PSA test had higher diagnoses of prostate cancer than those who...
Breast cancer screening using MRI versus mammography associated with more biopsies but lower cancer...
1. In women both with and without personal history of breast cancer (PHBC), screening MRI was associated with higher biopsy rates compared to mammography.
2....
Treatment-free remission of chronic myeloid leukemia possible after second-line nilotinib
1. Phase 2, open-label study results suggest that treatment-free remission (TFR) of chronic myeloid leukemia (CML) for ≥48 weeks can be reached by over...
