Oncology

Reports of high-impact oncology studies by medical professionals

Melanoma as a possible cause of autoimmune encephalitis

1. A woman developed anti-AMPA receptor encephalitis in the setting of metastatic melanoma.2. Following a short delay, she responded well to vemurafenib and cobimetinib....

Quick Take: Association of Disease Recurrence With Survival Outcomes in Patients With Cutaneous Squamous...

Cutaneous squamous cell carcinoma of the head and neck (cSCC-HN) generally has a favorable prognosis, however, there is a subset of patients who experience...

Quick Take: Association of Digital Breast Tomosynthesis vs Digital Mammography With Cancer Detection and...

The use of digital breast tomosynthesis (DBT) has been associated with increases in specificity and breast cancer detection compared with digital mammography (DM) alone....

The LION trial: systemic lymphadenectomy in advanced ovarian cancer patients provides no survival benefits

1. Pelvic and paraaortic lymphadenectomy in advanced ovarian cancer patients provided no overall or progression-free survival benefits compared to patients not undergoing lymphadenectomy.2. Serious...

Quick Take: Effects of a Thermal Accelerant Gel on Microwave Ablation Zone Volumes in...

Image-guided thermal ablation is used as a cancer treatment modality; however, local tumor progression continues to be a problem. Thermal accelerant use has been...

Quick Take: Association between Periprocedural Neutropenia and Early Infection-related Chest Port Removal

Implantable subcutaneous chest ports are used in maintaining long-term central venous access. The use of these ports is common in a number of clinical...

The KATHERINE trial: trastuzumab emtansine more effective than trastuzumab alone for treating residual HER2-positive...

1. Patients with residual human epidermal growth factor receptor 2 (HER2)-positive breast cancer after chemotherapy and HER2 targeted therapy had higher disease-free survival if...

Quick Take: Hypofractionated versus conventional fractionated postmastectomy radiotherapy for patients with high-risk breast cancer:...

Breast-conserving surgery or mastectomy followed by radiotherapy is commonly used in the treatment of early-stage breast cancer. There is growing interest in delivering postmastectomy...

De novo design of artificial IL-2 mimic for the treatment of cancer [PreClinical]

1. IL-2 is a central cytokine that enhances the immune response, with considerable potential for the treatment of cancer.2. A mimic of IL-2 binds...

Quick Take: Accelerated hypofractionated radiation therapy for elderly frail bladder cancer patients unfit for...

The standard of care for T2-T4aN0M0 muscle-invasive bladder cancer (MIBC) and high-risk non-MIBC in fit patients is radical cystectomy (RC). In patients unfit for...
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