Oncology

Reports of high-impact oncology studies by medical professionals

Quick Take: Breast Cancer Recurrence in the Nipple-Areola Complex After Nipple-Sparing Mastectomy With Immediate...

Nipple-sparing mastectomy (NSM) in the setting of breast cancer preserves the nipple-areola complex (NAC) and breast skin envelope. While previous studies have shown that...

The STORM trial: treatment refractory multiple myeloma patients experience response with selinexor

1. Approximately a quarter of multiple myeloma patients that had refractory disease despite treatment with a proteasome inhibitor, immunomodulatory agent, and daratumumab experienced treatment...

Quick Take: Medium and long-term risks of specific cardiovascular diseases in survivors of 20...

With the large and growing population of cancer survivors over the last several decades, there exists significant concern that these patients may be at...

Quick Take: Pregnancy duration and endometrial cancer risk

Full-term pregnancies are strongly associated with a reduced risk of endometrial cancer. Whether this protective association is driven by fecundity, a specific process that...

Quick Take: T-Cell Receptor Gene Therapy for Human Papillomavirus–Associated Epithelial Cancers: A First-in-Human, Phase...

Genetically engineered T-cell therapies, such as chimeric antigen receptor T-cells (CAR T-cells), have been approved for the treatment of hematologic malignancies, however, there are...

Lipophilic statins associated with reduced risk for hepatocellular carcinoma

1. In this prospective propensity score (PS)-matched cohort study, lipophilic statins were found to significantly reduce incidence and mortality of hepatocellular carcinoma (HCC).2. No...

Quick Take: Diagnostic Yield of One-Time Colonoscopy vs One-Time Flexible Sigmoidoscopy vs Multiple Rounds...

The most common colorectal cancer (CRC) screening methods are colonoscopy, flexible sigmoidoscopy (FS), and fecal immunochemical testing (FIT). The diagnostic yield of any screening...

Quick Take: Assessment of long-term distant recurrence-free survival associated with tamoxifen therapy in post-menopausal...

Most estrogen receptor (ER)-positive breast cancers can be classified as luminal A or luminal B subtype. It has been estimated that 1 in 4...

Quick Take: Overall survival with ribociclib plus endocrine therapy in breast cancer

Hormone therapy is the standard of care for premenopausal and postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor2 (HER2)-negative advanced breast cancer....

Quick Take: Erdafitinib in locally advanced or metastatic urothelial carcinoma

Second-line single-agent chemotherapies or immune checkpoint inhibitors have provided suboptimal response rates and survival benefits in patients with locally advanced and unresectable or metastatic...
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