Testosterone replacement in male cancer survivors helps improve body composition
1. Young male cancer survivors with low-normal serum morning total testosterone benefited from testosterone treatment as a therapeutic option to improve body composition.
Evidence Rating:...
MRI-targeted biopsies alone may underestimate grade of prostate cancer
1. In this prospective cohort, MRI-targeted biopsies alone, underestimated the histologic grade of prostate cancer tumors.
2. The combination of MRI targeted biopsy and systematic...
Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes
1. Luspatercept may significantly reduce transfusion burden in patients with lower-risk myelodysplastic syndromes with ring sideroblasts for whom erythropoiesis-stimulating agents have not been effective.
Evidence...
Annual mammography past 75 years of age not associated with reductions in mortality
1. In this observational study involving women aged 70 to 84 years with a life expectancy of at least 10 years, continuing screening past...
Adolescent obesity and midlife cancer risk
1. Adolescent obesity was significantly associated with cancer incidence in young and mid adulthood, and could be an important intervention target for early cancer...
Association of Use of Oral Contraceptives With Depressive Symptoms Among Adolescents and Young Women
1. Adolescent females using oral contraceptives may be at an increased risk of concurrent depressive symptoms.
Evidence Rating Level: 1 (Excellent)
Previous studies have indicated that...
Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube have similar outcomes
1. In patients with malignant pleural effusions, this randomized control trial of thoracoscopic talc poudrage versus talc slurry administered via chest tube found no...
Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma...
1. Immune-related adverse events are associated with a longer recurrence-free survival in patients with stage III melanoma treated with pembrolizumab.
Evidence Rating Level: 1 (Excellent)
Immune-related adverse...
Patient-Reported Functional Outcomes After Hypofractionated or Conventionally Fractionated Radiation for Prostate Cancer
1. In men with prostate cancer, functional outcomes following moderately hypofractionated radiation therapy are clinically equivalent to those following conventionally fractionated radiation therapy.
Evidence Rating...
Cost effectiveness of extending human papillomavirus vaccine administration until age 45
1. The FDA approved the expansion of the human papillomavirus (HPV) vaccination from ages 9 to 26 in women and 21 in men to...
