Enzalutamide treatment increases median overall survival in non-metastatic prostate cancer
1. Enzalutamide along with androgen-deprivation therapy was shown to significantly increase median overall survival among men with non-metastatic, castration-resistant prostate cancer.
2. Adverse events for...
Incidence of thyroid cancer in World Trade Center exposed firefighters
1. Fire Department World Trade Center-exposed workers demonstrate more asymptomatic thyroid cancers, attributable to occult lesion diagnoses, compared to non-WTC-exposed subjects of the Rochester...
Atezolizumab-bevacizumab treatment increases survival in unresectable hepatocellular carcinoma
1. Combination treatment of atezolizumab and bevacizumab was shown to significantly increase overall survival and progression-free survival outcomes in patients with advanced unresectable hepatocellular...
Decreased risk of ovarian cancer in women who have breastfed
1. Breastfeeding was found to be significantly associated with decrease risk of invasive ovarian cancer, including high-grade serous and endometroid cancer.
Evidence Rating: 2 (Good)
Ovarian...
Inhibition of inflammation through interleukin pathway may be protective against anemia
1. In this secondary analysis of data from the CANTOS trial in 2017, canakinumab significantly reduced the incidence of anemia in patients with a...
Testosterone replacement in male cancer survivors helps improve body composition
1. Young male cancer survivors with low-normal serum morning total testosterone benefited from testosterone treatment as a therapeutic option to improve body composition.
Evidence Rating:...
MRI-targeted biopsies alone may underestimate grade of prostate cancer
1. In this prospective cohort, MRI-targeted biopsies alone, underestimated the histologic grade of prostate cancer tumors.
2. The combination of MRI targeted biopsy and systematic...
Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes
1. Luspatercept may significantly reduce transfusion burden in patients with lower-risk myelodysplastic syndromes with ring sideroblasts for whom erythropoiesis-stimulating agents have not been effective.
Evidence...
Annual mammography past 75 years of age not associated with reductions in mortality
1. In this observational study involving women aged 70 to 84 years with a life expectancy of at least 10 years, continuing screening past...
Adolescent obesity and midlife cancer risk
1. Adolescent obesity was significantly associated with cancer incidence in young and mid adulthood, and could be an important intervention target for early cancer...
