Oncology

Reports of high-impact oncology studies by medical professionals

Sentinel lymph node dissection not inferior to complete axillary lymph node dissection for women...

1. For women with invasive breast cancer and metastases to 1 or 2 sentinel lymph nodes, treatment with sentinel lymph node dissection alone was...

Hormone replacement therapy not associated with changes in mortality in post-menopausal women

1. In this analysis of two randomized controlled trials, hormone replacement therapy (HRT) was not associated with a change in all-cause mortality among post-menopausal...

Outreach efforts improve rates of colon cancer screening

1. This randomized clinical trial showed that among persons aged 50-64 years, mailed outreach invitations offering either fecal immunochemical tests (FIT) or colonoscopies increased...

Physician notification increases patient participation in colorectal cancer screening

1. Providing physicians with a list of patients requiring colorectal cancer screening results in a small but significant increase in patient participation in fecal...

Re-analysis of evidence suggests that PSA screening significantly reduces the risk for death from...

1. PSA screening was associated with a reduction in risk for death from prostate cancer. 2. No differences in the effects of PSA screening were...

Small-molecule inhibitor may reduce chemotherapy-associated metastases [PreClinical]

1. In a mouse model of breast cancer, treatment with the chemotherapy paclitaxel (Ptx) enhanced tumor cell dissemination and the formation of micrometastatic lung...

Extensive cancer screening may not improve outcomes for patients with unprovoked venous thromboembolism

1. Although more extensive screening may detect more cases of occult cancer in patients with unprovoked venous thromboembolism (VTE) at the preliminary screening, it...

Limited evidence available to determine effectiveness and safety of cannabis to treat chronic pain

1. There is some evidence that cannabis reduces neuropathic pain, but there is inadequate evidence for other pain types. 2. Possible harms of cannabis use...

Plasma Epstein–Barr virus DNA useful for nasopharyngeal carcinoma screening

1. Asymptomatic study participants with persistently elevated serum Epstein-Barr virus (EBV) levels were diagnosed with nasopharyngeal carcinoma at rates higher than expected without screening. 2....

Osteoporosis medications may improve bone health in men receiving androgen deprivation therapy for prostate...

1. Bisphosphonates and denosumab increased bone mineral density (BMD) in men receiving androgen deprivation therapy (ADT) for nonmetastatic prostate cancer, with denosumab also showing...
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