FDA highlights flexible chemistry manufacturing controls expectations for cell and gene therapies
1. New FDA communication introduces a more flexible, risk‑based chemistry, manufacturing, and controls (CMC) framework for cell and gene therapies,...
1. New FDA communication introduces a more flexible, risk‑based chemistry, manufacturing, and controls (CMC) framework for cell and gene therapies,...
1. Surgery-induced weight loss was associated with lower cancer incidence and mortality rates in women with obesity, but not men....
1. In this cohort study, a novel prognostic model was developed to estimate prostate cancer-specific mortality (PCSM) while accounting for...
1. In patients with advanced cancer who are not hypoxemic, high-flow nasal therapy using room air and simple fan therapy...
1. Among patients with high-risk, early-stage triple-negative breast cancer, the addition of carboplatin to a standard anthracycline/taxane adjuvant chemotherapy regimen...
1. In this retrospective cohort study, most patients with a positive lung cancer screening result received guideline-concordant follow-up, though nearly...
1. In this prospective cohort study, duration-based criteria reduced racial disparities in lung cancer screening eligibility, increasing access for minority...
1. In this randomized controlled trial, breast density notification was associated with increased anxiety and confusion without helping women feel...
1. In this systematic review and meta-analysis, use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) was not associated with a significant...
1. An N-terminal pro–B-type natriuretic peptide (NT-proBNP)-guided approach to neurohormonal therapy for cardioprotection in patients receiving anthracyclines for breast cancer...
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