Infectious Disease

Reports of high-impact infectious disease studies by medical professionals

Oral neonatal rotavirus vaccine RV3-BB effective in preventing severe gastroenteritis

1. Newborns receiving the oral human neonatal rotavirus vaccine (RV3-BB) with the first dose occurring either at birth or at 8 weeks experienced fewer...

Complex government-mandated sepsis performance measures not shown to improve survival

1. No moderate- or high-level evidence was found that SEP-1 or its hemodynamic interventions increase survival in septic adults. 2. The authors suggest that the...

Opioid use associated with increased risk of invasive pneumococcal disease

1. Researchers found a strong link between prescription opioid use and the risk for invasive pneumococcal disease (IPD). 2. The strongest link was present in...

Maternal vaccination during pregnancy not associated with infant hospitalization, mortality

1. No significant association was identified between maternal intrapartum vaccination with the influenza or tetanus, diphtheria, and acellular pertussis (Tdap) vaccine and infant hospitalization...

Influenza vaccine not associated with increased risk of epilepsy in children

1. No increased risk of incident epilepsy was seen among children who received influenza vaccination during the 2009-2010 influenza season in Norway. Evidence Rating Level:...

Mogamulizumab is safe and possibly effective in HTLV-1-associated myelopathy

1. In this combined phase 1-2a study, mogamulizumab used for treatment of human T-lymphotropic virus type 1 (HTLV-1) associated myelopathy was safe and associated...

Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure...

1. For predicting short-term mortality in patients with suspected infection, quick Sequential Organ Failure Assessment (qSOFA) had moderate specificity and poor sensitivity. 2. The systemic...

AAP policy statement discusses recommended immunizations

1. The 2018 version of the Recommended Childhood and Adolescent Immunization Schedule has been published by the American Academy of Pediatrics and approved by...

Recurrent Salmonella enterica Typhimurium infection disables host protection against intestinal inflammation [PreClinical]

1. Repeated gastrointestinal infections in mice, in this case Salmonella enterica Typhimurium (ST), caused intestinal tissue inflammation which escalated with repeated infections. 2. Increased turnover...

Viral respiratory infections associated with increased risk of acute myocardial infarction

1. In a self-controlled case series, patients were observed to have increased incidence of hospital admissions for acute myocardial infarction (MI) within seven-days of...
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