A Zika vaccine could virtually eliminate prenatal infections
1. Zika virus shown to be of moderate to high efficacy in eliminating prenatal infections.
2. Vaccine provides 90% coverage and is targeted for immunization...
Quadrivalent recombinant influenza vaccine noninferior to inactivated vaccine
1. The quadrivalent recombinant influenza vaccine (RIV4) was noninferior when compared with the quadrivalent inactivated influenza vaccine (IIV4) for immunogenicity.
Evidence Rating Level: 1 (Excellent)
Study...
HIV incidence has decreased overall, but remains higher among minority men who have sex...
1. Overall HIV incidence in the United States has decreased in all high-risk transmission groups except for minority men who have sex with men...
Flucytosine plus fluconazole is noninferior to amphotericin B in treating cryptococcal meningitis
1. Treatment of cryptococcal meningitis with two weeks of flucytosine and fluconazole was noninferior to two weeks of amphotericin B.
2. Addition of flucytosine to...
Compliance-linked incentives increase infant immunizations rates in rural India
1. Infantile immunization rates were higher among children whose caregivers received compliance-linked incentives when compared to those who received only mobile phone reminders and...
No difference between tenofovir and placebo in reducing perinatal transmission of hepatitis B
1. Hepatitis B e-antigen (HBe-Ag) positive mothers receiving tenofovir daily from 28-weeks gestation to 2 months postpartum did not show significant reductions in HBV...
HCV-infected kidney donors could save lives
1. No HCV infection was detected in patients receiving HCV-infected kidneys 12 weeks following treatment.
2. No antiviral treatment-related complications occurred recipients of HCV-infected kidneys.
Evidence...
Hydrocortisone plus fludrocortisone decreases mortality in adults with septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality...
Adjunctive glucocorticoid therapy does not lower mortality in septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone infusion, did not have...
Early diagnosis of HIV infection through analysis of oral fluid [Pre-Clinical]
1. A novel method – Antibody Detection by Agglutination-PCR (ADAP) – was developed to diagnose HIV in oral fluid samples.
2. ADAP is both highly...
