More data needed to determine safety of probiotics and prebiotics
1. Studies are often lacking or inadequate with respect to reporting adverse events (AEs) related to probiotics and prebiotics.
2. The majority of the studies...
Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients...
1. Use of HCV-infected kidneys increased patients’ quality-adjusted life expectancy.
2. Lower costs were associated with HCV-infected kidneys compared to transplanting HCV-uninfected kidneys to HCV-positive...
Primary HPV testing may detect cervical neoplasms earlier and more accurately than cytology
1. In this Canadian, randomized controlled trial, the use of primary HPV testing compared with cytology resulted in a significantly lower likelihood of CIN3+...
Most commonly used HIV drug worldwide not associated with increased risk for suicide in...
1. No baseline differences observed between patients exposed to efavirenz and nevirapine compared to those never exposed, regarding both depression and suicide.
2. No significant...
Drug treatment associated with a significant reduction in death risk following opioid overdose
1. Buprenorphine and methadone maintenance treatment (MMT) was associated with reduced death in opioid users.
2. No significant associations were found between naltrexone and all-cause...
Failures in using personal protective equipment are commonly observed
1. In this qualitative study, active failures in infectious agent transmission precaution practices were observed frequently.
2. Common failures include: failure to enter room with...
No benefit of negative pressure wound therapy for lower extremity open fractures
1. In this randomized controlled trial, there was no difference in the self-reported disability 12 months after injury between patients treated with negative pressure...
Surveillance of DTaP Vaccines Reveals No New Safety Concerns
1. Surveillance of adverse events after diphtheria-tetanus-acellular pertussis (DTaP) vaccine administration reported to the Vaccine Adverse Event Reporting System (VAERS) between 1991 and 2016...
Viruses not linked to asthma exacerbation severity
1. Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.
Evidence Rating Level: 2 (Good)
Study Rundown: Viral...
Physicians should look for misuse patterns that lead to overdose before prescribing opioids
1. All opioid misuse patterns examined had a positive association with opioid overdose and death.
2. High number of prescribers and/or pharmacies was a key...
