Dolutegravir-containing antiretroviral regimens show effective viral suppression in pregnant women with HIV-1 infections
1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission.
2. Dolutegravir, emtricitabine, and tenofovir alafenamide...
Post-COVID Syndrome is linked to higher mortality risk and multi-organ dysfunction
1. Hospital readmission and mortality rates were higher in post-COVID patients as compared to matched control groups.
2. More diagnoses of respiratory disease, diabetes, and...
Targeted intervention improved Infant Bronchiolitis treatment by deimplementing ineffective management practices
1. Targeting specific ineffective bronchiolitis treatment practices and further educating hospital staff on appropriate treatment was more effective at deimplementing inappropriate treatment, compared to...
Clinical outcomes of infants breastfeeding from mothers with COVID-19
1. A small study of Israeli neonates with COVID-19-positive mothers found no transmission of SARS-CoV-2 to the neonates from feeding on unpasteurized maternal breast...
Initial effects of COVID-19 on patients with end-stage kidney disease
1. Patients with end-stage kidney disease were at increased risk of COVID-19-related mortality, particularly among non-Hispanic Black patients.
Evidence Rating Level: 3 (Average)
End-stage kidney disease...
Mood disorders and outcomes of COVID-19 hospitalizations
1. Mood disorder diagnoses prior to hospitalization for COVID-19 was associated with increased risk of in-hospital mortality after Day 12.
2. Prior mood disorders were...
Post-COVID syndrome associated with significant morbidity and mortality beyond respiratory illnesses
1. Hospital readmission and all-cause mortality rates are 3.5 and 7.7 times higher in COVID-19 patients after discharge, than the general population.
2. In addition...
Protection from SARS-CoV-2 re-infection may be diminished among elderly individuals
1. Prior infection with SARS-CoV-2 in the first wave (i.e. before June 2020) was linked to significant protection against reinfection in the second wave...
Clinical practice algorithm reduces endotracheal aspirate cultures in PICU
1. In a single center quality improvement project, implementation of a clinical practice algorithm in mechanically ventilated patients in the pediatric ICU lead to...
No association found between 9-valent Human Papillomavirus Vaccine During Pregnancy and adverse pregnancy outcomes
1. No significant increase in spontaneous abortion, preterm birth, major structural defects, or small for gestational age rates were found in women receiving 9vHPV...
