Cost effectiveness of extending human papillomavirus vaccine administration until age 45
1. The FDA approved the expansion of the human papillomavirus (HPV) vaccination from ages 9 to 26 in women and 21 in men to...
Typhoid vaccine Phase 3 trial in Nepal
1. In Nepal, the typhoid conjugate vaccine has proven to be very effective in protecting against typhoid fever.2. The typhoid antibody titers more than...
Association between use of multiple classes of antibiotic in infancy an allergic disease in...
1. Commonly prescribed antibiotics in infancy are associated with later diagnosis of allergic disease in childhoodEvidence Rating Level: 2 (Good)The use of antibiotics negatively...
Expanding heart transplant in the era of direct-acting antiviral therapy for hepatitis C
1. The rate of hepatitis C virus (HCV) transmission from nucleic acid amplification testing (NAT)-negative donor hearts is low, and survival rates in patients...
Immune Status and Associated Mortality After Cancer Treatment Among Individuals With HIV in the...
1. Chemotherapy and/or radiotherapy may provoke significant declines in CD4 counts in HIV patients as compared to other treatments, which in turn are associated...
Long-term impact of an educational antimicrobial stewardship programme in primary care on infections caused...
1. A multi-modal antimicrobial stewardship program in primary care focused on individual educational interviews may improve antibiotic prescription practices and lead to sustained reductions in...
Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi...
1. Enterotoxigenic Escherichia coli vaccination may provide significant immunogenic benefits in young children and infants in low- and middle-income countries with minimal associated toxicity.Evidence...
Global and regional estimates of the contribution of herpes simplex virus type 2 infection...
1. Herpes simplex virus type 2 (HSV-2) infections significantly contribute to the global burden of sexually-acquired HIV infections.Evidence Rating Level: 2 (Good)There is a...
Outcomes not improved with early amoxicillin-clavulanate in cardiac arrest patients
1. A 2-day course of amoxicillin-clavulanate and targeted temperature management of 32-34 degrees Celsius after cardiac arrest with shockable rhythm resulted in a lower...
Daily colchicine after myocardial infarction lowers risk of subsequent event
1. Colchicine given to patients after a myocardial infarction led to a significantly lower risk of death from cardiovascular causes, resuscitations, myocardial infarctions, stroke,...
