Rapid respiratory pathogen testing does not significantly alter antibiotic prescription rates among children with...
1. When treating children with an acute respiratory illness in the emergency department, no significant difference in antibiotic prescription rates was observed when clinicians...
Convalescent plasma does not improve survival in patients hospitalized with COVID-19
1. A similar proportion of patients died within 28 days of randomization in both groups (high-titre convalescent plasma vs. usual care).
2. Allocation to convalescent...
Maternal influenza vaccine during pregnancy not linked to adverse early childhood outcomes
1. Over a mean follow-up period of 3.6 years, no significant association was detected between maternal influenza vaccination during pregnancy and early childhood health...
Shorter antibiotic therapy for prosthetic joint infection caused worse outcomes
1. A six-week antibiotic therapy was not shown to be non-inferior to a 12-week antibiotic therapy for patients with confirmed prosthetic joint infections.
2.The six-week...
Study outlines trends in pediatric toxic ingestions during the COVID-19 pandemic
1. In this national study of poison control center reports, there was an absolute decrease in reported pediatric ingestions during the first year of...
Net fluid balance not associated with hospital readmission rates among sepsis patients
1. There was no association found between positive fluid balance at the time of discharge and readmission at 30 days post-discharge in non-critically ill...
Tympanostomy tubes not superior to medical management for recurrent acute otitis media
1. Tympanostomy tubes were not shown to be superior to medical management for recurrent acute otitis media.
2. There was no substantial difference for elevated...
Randomized trial of plant-derived vaccine for COVID-19
1. A plant-derived, virus-like particle displays the SARS-CoV-2 spike glycoprotein and appears to be a promising candidate for a vaccine.
2. Adverse outcomes were mild-to-moderate,...
Comorbid cancer and systemic therapy may influence immune response to SARS-CoV-2 among patients and...
1. In this cross-sectional study of Japanese patients with cancer and health care workers, the seroprevalence of SARS-CoV-2 antibodies did not differ between the...
Critically ill COVID-19 patients in Africa may have worse outcomes compared to global rates...
1. In-hospital mortality within 30 days of admission for COVID-19 was 48% (vs. global mortality 31.5%).
2. Increased age, underlying comorbidities and delay in admission...
