Quick Take: Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind,...
Several recently published guidelines regarding the treatment of C. difficile infection recommend vancomycin as first-line antibiotic treatment. However, given the recent increase in severity...
The POET trial: oral antibiotics in stable endocarditis patients noninferior to intravenous treatment
1. Patients with left sided infective endocarditis who switched to oral antibiotics once stable had similar composite adverse event outcomes compared to patients treated...
Antibiotic therapy for asthma exacerbation associated with longer hospital stay
1. In this retrospective cohort study looking at patients admitted with asthma exacerbations and treated with corticosteroids, antibiotic administration within the first two days,...
The OVIVA trial: oral antibiotics noninferior to intravenous antibiotics for bone and joint infections
1. Patients with bone and joint infections treated with 6 weeks of oral or intravenous antibiotic therapy had similar rates of treatment failure after...
Quick Take: Prior dengue virus infection and risk of Zika: a pediatric cohort in...
Acute Zika infection is often asymptomatic, though affected individuals commonly present with symptoms including rash, low-grade fever, arthralgias and conjunctivitis. The virus responsible, Zika...
HPV vaccine effective against infection and for herd immunity
1. Human papillomavirus (HPV) vaccine decreased infection rates among vaccinated women by 70-80%, depending on vaccine type2. Infection with 4-valent vaccine-type HPV among unvaccinated...
The DETECTIVE trial: tafenoquine reduces risk of Plasmodium vivax relapse
1. After initial chloroquine treatment, P. vivax malaria infected patients treated with tafenoquine had significantly lower rates of P. vivax infection at 6 months...
Screening all donated blood for Zika virus is not cost-effective in the United States
1. This microsimulation study suggested that screening blood for Zika virus is only cost-effective during the high mosquito season in Puerto Rico.2. The authors...
Meningococcus B rates higher among college students compared with noncollege peers
1. College students were at significantly higher risk of contracting meningococcus serotype B (MenB) disease compared with noncollege students in the same age group.2....
Mupirocin effective in Staphylococcus aureus decolonization in neonates
1. Mupirocin was shown to have an overall primary decolonization efficacy of 95% when used to treat Staphylococcus aureus among infants <24 months old...
