Optogenetic therapy may partially restore vision in retinitis pigmentosa
1. In this phase 1 trial involving subjects with advanced retinitis pigmentosa, optogenetic therapy was associated with improved light sensitivity...
Giredestrant plus everolimus improves progression-free survival in treatment-resistant breast cancer
1. In this randomized controlled trial involving patients with disease progression during first-line treatment for breast cancer, giredestrant plus everolimus...
Anitocabtagene autoleucel associated with sustained clinical response in heavily pretreated multiple myeloma
1. In this phase 1 trial involving patients with triple-class refractory multiple myeloma, treatment with anitocabtagene autoleucel led to a...
Gene therapy shows sustained benefit in Wiskott–Aldrich syndrome
1. In this analysis of data from over two dozen individuals with Wiskott-Aldrich syndrome, treatment with etuvetidigene autotemcel (etu-cel) was...
High maternal egg-peanut intake not associated with reduced infant allergy
1. In this randomized controlled trial, high maternal consumption of eggs and peanuts during pregnancy and lactation did not reduce...
Historical redlining associated with lower breast cancer screening across urban neighborhoods
1. In this retrospective cohort study, historically redlined grade C and D Census tracts had lower breast cancer screening rates...
N-methylaniline exposure identified as likely cause of methemoglobinemia during maritime migration
1. In this case series of severe acquired methemoglobinemia among migrants to Italy, prolonged skin exposure to fuel-contaminated seawater was...
Video mental health care may have clinical advantages versus phone or in-person visits
1. In this retrospective cohort study, veterans receiving most outpatient mental health care by video had lower adjusted rates of...
Methadone initiation linked to lower mortality compared to buprenorphine-naloxone after opioid overdose
1. In this retrospective cohort study examining people who had survived a recent opioid overdose, initiating methadone was associated with...
Daraxonrasib showed antitumor activity in previously treated RAS-mutant non–small-cell lung cancer
1. In patients with previously treated advanced RAS-mutant non–small-cell lung cancer, daraxonrasib produced objective responses in approximately one-third of subjects...
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