Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

The 3 Wishes Project: a valuable program to improve end-of-life care

1. The 3 Wishes Project (3WP), which strives to provide humanistic care and honor the dignity of end-of-life (EOL) patients, was shown to be...

Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease

Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease1. Widespread cholinergic deficits found in early-onset Alzheimer’s disease (AD) may...

Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity...

1. Acetaminophen burden, as measured by cord plasma samples, was associated with increased, dose-dependent risk of childhood Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder.Evidence Rating...

Long-term cognitive behavioral therapy may reduce healthcare costs versus second-generation antidepressants

1. In this modeling study comparing the cost-effectiveness of cognitive behavioral therapy (CBT) with second-generation antidepressants (SGA) for initial treatment of depression, neither strategy...

Lung cancer screening according to existing guidelines is likely cost-effective

1. In this study comparing three prominent lung cancer screening strategies, all were found to be cost-effective, yielding incremental cost-effectiveness ratios of under $100,000/quality...

Metoprolol not effective in preventing exacerbations of chronic obstructive pulmonary disease

1. In this double-blind randomized trial of COPD patients without previous indication for beta blocker therapy, treatment with extended-release beta-blockers failed to generate improved...

Ticagrelor alone non-inferior after one month post drug eluting stent placement

1. In this pre-specified ancillary study of a randomized control trial, ticagrelor alone after one month was found non-inferior, but not superior, to dual...

Number of child psychiatrists is growing, but poor, rural areas remain underserved

1. A cross-sectional analysis of American Medical Association physician data between 2007 and 2016 indicated overall growth in the number of child psychiatrists per...

Trends in cardiovascular disease morbidity and mortality in American Indians over 25 years: the...

1. The incidence and mortality associated with cardiovascular disease has decreased over a generation in a Native American cohort, however, improvements in age-specific mortality...

Association of body mass index and extreme obesity with long-term outcomes following percutaneous coronary...

1. Patients with obesity undergoing percutaneous coronary intervention are typically younger with more cardiovascular risk factors, but may be less likely to experience procedural...
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