Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

No benefit of sodium bicarbonate or acetylcysteine for prevention of complications after angiography: The...

1. Amongst patients undergoing angiography, neither sodium bicarbonate nor acetylcysteine were effective in preventing a composite outcome of death, need for dialysis, or persistent...

Nusinersen improves motor function in children with later-onset spinal muscular atrophy: The CHERISH trial

1. Intrathecal injections of nusinersen in pediatric later-onset spinal muscular atrophy (SMA) patients were associated with increased clinical motor function scores compared to sham...

Quality of care for transient ischemic attack and minor stroke vary across country

1. In this study about quality of care for patients with TIA or minor stroke, there was substantial variation in adherence to guidelines for...

ICD placement in CKD patients increases hospitalizations without survival benefit

1. Adults with chronic kidney disease (CKD) and heart failure with reduced LVEF who received implantable cardioverter defibrillators (ICDs) did not differ from matched...

Prazosin and placebo exhibit similar efficacy in post-traumatic stress disorder: The PACT trial

1. In patients with nocturnal symptoms of post-traumatic stress disorder (PTSD), prazosin did not significantly reduce nightmares or improve quality of sleep compared to...

Mogamulizumab is safe and possibly effective in HTLV-1-associated myelopathy

1. In this combined phase 1-2a study, mogamulizumab used for treatment of human T-lymphotropic virus type 1 (HTLV-1) associated myelopathy was safe and associated...

Fetal alcohol spectrum disorders likely to be vastly underdiagnosed in US

1. A multisite, cross-sectional study found a large mismatch between previously diagnosed fetal alcohol spectrum disorders and the actual prevalence of cases identified. Evidence Rating...

Preoperatively diagnosed patent foramen ovale linked to increased perioperative stroke risk

1. A preoperatively diagnosed patent foramen ovale was associated with an increased risk of stroke within 30 days of non-cardiac surgery. Evidence Rating Level: 2...

Hot tea consumption associated with increased esophageal cancer risk in high-risk individuals

1. Hot tea consumption in combination with excessive smoking or alcohol use was associated with a higher risk for esophageal cancer. 2. In the absence...

Pharmacist-led extended medication review and follow-up on discharge may decrease risk of readmission

1. In this randomized clinical trial, a pharmacist-led extended intervention, which included medication review, three motivational interviews, and telephone follow-up resulted in significant decreases...
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