Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Multidisciplinary approach linked with increased utilization of peritoneal dialysis for new dialysis patients

1. In this retrospective quality improvement cohort study from the United States, a multidisciplinary approach was linked with increased rates of peritoneal dialysis initiation...

Soft drink consumption linked with increased all-cause mortality

1. In this population-based cohort study, consumption of total, sugar-, and artificially-sweetened soft drinks was linked with an increased risk of all-cause mortality.2. The...

Quick Take: HbA1c level as a risk factor for retinopathy and nephropathy in children...

Intensive glycemic control has been shown to reduce the risk of retinopathy and nephropathy in the setting of type 1 diabetes. While prior studies...

#VisualAbstract: Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients...

Most estrogen receptor (ER)-positive breast cancers can be classified as luminal A or luminal B subtype. It has been estimated that 1 in 4...

The CLASS trial: laser ablation and surgery improve quality-of-life for varicose vein patients compared...

1. In patients with primary varicose veins followed for 5 years after treatment, those randomized to receive laser ablation or surgery reported greater improvements...

The RELAX-AHF-2 trial: serelaxin provides no mortality benefit in acute heart failure patients

1. Patients hospitalized with acute heart failure (AHF) randomized to receive the vasodilator serelaxin experienced similar occurrence of death from heart failure at 180...

The NAMSAL ANRS 12313 trial: HIV viral suppression similar for dolutegravir and low-dose efavirenz...

1. For previously untreated HIV-1 patients in Cameroon, treatment with dolutegravir was noninferior to low dose efavirenz at lowering viral load over a period...

Quick Take: Evaluation of the Central Vein Sign as a Diagnostic Imaging Biomarker in...

Diagnosing multiple sclerosis (MS) is challenging, in part because imaging findings in MS partially overlap with MS mimics such as vascular disease, migraine, and...

Quick Take: Association of Childhood-Onset Inflammatory Bowel Disease With Risk of Psychiatric Disorders and...

Childhood-onset inflammatory bowel disease (IBD) typically has a more severe course than adult-onset IBD, and has been found to be associated with psychiatric morbidity...

The STORM trial: treatment refractory multiple myeloma patients experience response with selinexor

1. Approximately a quarter of multiple myeloma patients that had refractory disease despite treatment with a proteasome inhibitor, immunomodulatory agent, and daratumumab experienced treatment...
licensing as small

All-time hits