SGLT-2 inhibitors and GLP-1 agonists associated with better mortality outcomes than DPP-4 inhibitors for...
1. SGLT-2 or GLP-1 agonists were associated with lower mortality than DPP-4 inhibitors, placebo, or no treatment.
2. Use of DPP-4 inhibitors was not associated...
Intensive LDL-C lowering reduces mortality in patients with higher baseline LDL-C
1. In this systematic review and meta-analysis, more intensive compared with less itensive LDL-C lowering was associated with a greater reduction in risk of...
Centrifugal-flow pumps improve complication free survival compared to axial flow-pumps: The MOMENTUM 3 trial
1. Advanced heart failure patients randomized to receive centrifugal-flow pumps demonstrated higher rates of 2-year survival free of disabling stroke or reoperation to remove...
Optimizing organ donations from overdose deaths may help address national organ shortage
1. U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from organs donated by ODDs...
Higher short-term mortality demonstrated for women compared with men after ST-elevation myocardial infarction
1. In a modern cohort of patients with readily available primary percutaneous coronary intervention, woman experienced greater mortality rates then men following ST-elevation myocardial...
Medicare pre-ESRD care results in more dialysis initiation but also increased two-year mortality
1. Veterans receiving pre-end stage renal disease (ESRD) nephrology care in under the Medicare system were more likely to undergo dialysis and had a...
No association of overweight childhood and adult type 2 diabetes risk after weight loss
1. Compared to men who were never overweight, those overweight at age 7 who returned to a normal body mass index (BMI) by age...
Barber facilitated health promotion reduces blood pressure among black male barber patrons
1. Non-Hispanic black male barber patrons prescribed antihypertensive therapy with barber encouragement along with lifestyle modification experienced greater reductions in blood pressures compared to...
Health burden varies significantly by state in the US
1. In the US Burden of Disease Report, the leading causes of death were ischemic heart disease, lung cancer, chronic obstructive pulmonary disease (COPD),...
BEACON CRC Safety Lead-in Study suggests safety and efficacy of triplet combination therapy for...
1. BEACON CRC is a multicenter, randomized, phase 3 clinical trial evaluating the triplet combination of binimetinib (BINI, a MEK inhibitor) + encorafenib (ENCO,...
