Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Rivaroxaban and warfarin have similar safety and efficacy in mild atrial fibrillation-related ischemic stroke

1. In this randomized controlled trial, rivaroxaban and warfarin were similar in safety and efficacy when used to prevent early recurrence of stroke in...

Sentinel lymph node dissection not inferior to complete axillary lymph node dissection for women...

1. For women with invasive breast cancer and metastases to 1 or 2 sentinel lymph nodes, treatment with sentinel lymph node dissection alone was...

Hormone replacement therapy not associated with changes in mortality in post-menopausal women

1. In this analysis of two randomized controlled trials, hormone replacement therapy (HRT) was not associated with a change in all-cause mortality among post-menopausal...

High recurrence of gastroesophageal reflux disease in patients treated with laparoscopic antireflux surgery

1. Among patients receiving laparoscopic antireflux surgery, 17.7% experienced recurrent GERD requiring medication or secondary antireflux surgery 2. Factors associated with recurrence included older age,...

Both total and uninterrupted sedentary time correlated with increased risk of mortality

1. Both a high total amount of sedentary time as well as its accumulation in lengthy, continuous stretches were linked to a higher risk...

Intensive blood pressure lowering linked to decreased mortality in patients with chronic kidney disease

1. In a meta-analysis of randomized trials evaluating blood pressure control in patients with stage 3-5 chronic kidney disease (CKD), more intensive blood pressure...

Total mucin concentration is associated with chronic bronchitis phenotype

1. Total airway mucin concentration was significantly elevated in current or former smokers with chronic bronchitis compared to non-smoker controls, and correlated with disease...

Tiotropium linked with improved outcomes in early-stage COPD

1. Patients with mild or moderate COPD (chronic obstructive pulmonary disease) randomized to receive tiotropium had a significantly higher FEV1 (forced expiratory volume in...

Outreach efforts improve rates of colon cancer screening

1. This randomized clinical trial showed that among persons aged 50-64 years, mailed outreach invitations offering either fecal immunochemical tests (FIT) or colonoscopies increased...

Physician notification increases patient participation in colorectal cancer screening

1. Providing physicians with a list of patients requiring colorectal cancer screening results in a small but significant increase in patient participation in fecal...
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